Patents by Inventor Cesar V. Borlongan
Cesar V. Borlongan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11351202Abstract: The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.Type: GrantFiled: December 20, 2017Date of Patent: June 7, 2022Assignees: ABT HOLDING COMPANY, AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.Inventors: Robert Mays, Robert J. Deans, David C. Hess, James E. Carroll, Cesar V. Borlongan
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Publication number: 20220118026Abstract: The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MPACs, in children, for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.Type: ApplicationFiled: December 20, 2021Publication date: April 21, 2022Applicants: ABT Holding Company, AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.Inventors: Robert MAYS, Robert J. DEANS, David C. HESS, James E. CARROLL, Cesar V. BORLONGAN
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Publication number: 20220110982Abstract: The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxis and that caused by insufficient blood supply. In some further particulars the invntion relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children, for example, and to the treatment of cortical infants and stroke with MAPCs in adults, for example.Type: ApplicationFiled: December 20, 2021Publication date: April 14, 2022Applicants: ABT Holding Company, AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.Inventors: Robert MAYS, Robert J. Deans, David C. Hess, James E. Carroll, Cesar V. Borlongan
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Publication number: 20210299185Abstract: The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.Type: ApplicationFiled: June 10, 2021Publication date: September 30, 2021Applicants: ABT Holding Company, AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.Inventors: Robert W. MAYS, Robert J. DEANS, David C. HESS, James E. CARROLL, Cesar V. BORLONGAN
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Publication number: 20200354709Abstract: Disclosed herein are methods for the treatment of traumatic brain injury by transplantation of cells descended from marrow adherent stem cells that express an exogenous Notch intracellular domain. The transplanted cells form a pathway along which endogenous neurogenic cells proliferate and migrate from the subventricular zone to the site of injury.Type: ApplicationFiled: March 5, 2020Publication date: November 12, 2020Applicants: SanBio, Inc., University of South FloridaInventors: Cesar V. BORLONGAN, Casey C. CASE
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Patent number: 10626389Abstract: Disclosed herein are methods for the treatment of traumatic brain injury by transplantation of cells descended from marrow adherent stem cells that express an exogenous Notch intracellular domain. The transplanted cells form a pathway along which endogenous neurogenic cells proliferate and migrate from the subventricular zone to the site of injury.Type: GrantFiled: February 26, 2019Date of Patent: April 21, 2020Assignees: SanBio, Inc., University of South FloridaInventors: Cesar V. Borlongan, Casey C. Case
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Publication number: 20190185839Abstract: Disclosed herein are methods for the treatment of traumatic brain injury by transplantation of cells descended from marrow adherent stem cells that express an exogenous Notch intracellular domain. The transplanted cells form a pathway along which endogenous neurogenic cells proliferate and migrate from the subventricular zone to the site of injury.Type: ApplicationFiled: February 26, 2019Publication date: June 20, 2019Applicants: SanBio, Inc., University of South FloridaInventors: Cesar V. BORLONGAN, Casey C. CASE
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Patent number: 10117900Abstract: The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.Type: GrantFiled: January 23, 2007Date of Patent: November 6, 2018Assignees: ATHERSYS, INC., Augusta University Research Institute, Inc.Inventors: Robert Mays, Robert J. Deans, David C. Hess, James E. Carroll, Cesar V. Borlongan
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Publication number: 20180296609Abstract: The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.Type: ApplicationFiled: December 20, 2017Publication date: October 18, 2018Applicant: AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC.Inventors: Robert MAYS, Robert J. Deans, David C. Hess, James E. Carroll, Cesar V. Borlongan
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Publication number: 20180117093Abstract: The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.Type: ApplicationFiled: January 23, 2007Publication date: May 3, 2018Applicant: ATHERSYS, INC.Inventors: Robert Mays, Robert J. Deans, David C. Hess, James E. Carroll, Cesar V. Borlongan
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Patent number: 9828593Abstract: Disclosed herein are methods for the treatment of traumatic brain injury by transplantation of cells descended from marrow adherent stem cells that express an exogenous Notch intracellular domain. The transplanted cells form a pathway along which endogenous neurogenic cells proliferate and migrate from the subventricular zone to the site of injury.Type: GrantFiled: March 13, 2013Date of Patent: November 28, 2017Assignees: SanBio, Inc., University of South FloridaInventors: Cesar V. Borlongan, Casey C. Case
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Publication number: 20150197741Abstract: Disclosed herein are methods for the treatment of traumatic brain injury by transplantation of cells descended from marrow adherent stem cells that express an exogenous Notch intracellular domain. The transplanted cells form a pathway along which endogenous neurogenic cells proliferate and migrate from the subventricular zone to the site of injury.Type: ApplicationFiled: September 18, 2014Publication date: July 16, 2015Inventors: Cesar V. Borlongan, Casey C. Case
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Publication number: 20100310570Abstract: The invention relates to the treatment of various injuries, disorders, dysfunctions, diseases, and the like of the brain with MAPCs, particularly in some aspects, to the treatment of the same resulting from hypoxia, including that caused by systemic hypoxia and that caused by insufficient blood supply. In some further particulars the invention relates, for example, to the treatment of hypoxic ischemic brain injury with MAPCs, in children for example, and to the treatment of cortical infarcts and stroke with MAPCs in adults, for example.Type: ApplicationFiled: January 23, 2007Publication date: December 9, 2010Applicant: ATHERSYS, INC.Inventors: Robert Mays, Robert J. Deans, David C. Hess, James E. Carroll, Cesar V. Borlongan
