Patents by Inventor Cesare Orlandi

Cesare Orlandi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of Mild and Moderate Alzheimer's Disease
    Publication number: 20190142803
    Abstract: The present invention relates to methods of treatment using [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl amine (“COMPOUND I”) or a pharmaceutically acceptable salt thereof. In various embodiments, the methods of treatment include treatment of mild-to-moderate dementia of Alzheimer's type, diabetes, insomnia, and other indications. The present invention also relates to pharmaceutical compositions comprising COMPOUND I or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: January 8, 2019
    Publication date: May 16, 2019
    Inventors: Cesare Orlandi, David J. Clark, Imogene M. Dunn, Maria Carmen Valcarce Lopez, Matthew J. Kostura
  • Treatment of Mild and Moderate Alzheimer's Disease
    Publication number: 20170326113
    Abstract: The present invention relates to methods of treatment using [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl amine (“COMPOUND I”) or a pharmaceutically acceptable salt thereof. In various embodiments, the methods of treatment include treatment of mild-to-moderate dementia of Alzheimer's type, diabetes, insomnia, and other indications. The present invention also relates to pharmaceutical compositions comprising COMPOUND I or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 23, 2017
    Publication date: November 16, 2017
    Inventors: Cesare Orlandi, David J. Clark, Imogene M. Dunn, Maria Carmen Valcarce Lopez, Matthew J. Kostura
  • Treatment of mild and moderate Alzheimer's disease
    Patent number: 9717710
    Abstract: The present invention relates to methods of treatment using [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl amine (“COMPOUND I”) or a pharmaceutically acceptable salt thereof. In various embodiments, the methods of treatment include treatment of mild-to-moderate dementia of Alzheimer's type, diabetes, insomnia, and other indications. The present invention also relates to pharmaceutical compositions comprising COMPOUND I or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: August 1, 2017
    Assignee: vTv THERAPEUTICS LLC
    Inventors: Cesare Orlandi, David J. Clark, Imogene M. Dunn, Maria Carmen Valcarce Lopez, Matthew J. Kostura
  • Treatment of Mild and Moderate Alzheimer's Disease
    Publication number: 20140100218
    Abstract: The present invention relates to methods of treatment using [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl amine (“COMPOUND I”) or a pharmaceutically acceptable salt thereof. In various embodiments, the methods of treatment include treatment of mild-to-moderate dementia of Alzheimer's type, diabetes, insomnia, and other indications. The present invention also relates to pharmaceutical compositions comprising COMPOUND I or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 22, 2013
    Publication date: April 10, 2014
    Applicant: TransTech Pharma, LLC
    Inventors: Cesare Orlandi, David J. Clark, Imogene M. Grimes, Maria Carmen Valcarce Lopez, Matthew J. Kostura
  • Method for detecting the cardiotoxicity of compounds
    Patent number: 5604112
    Abstract: The present invention provides methods of testing the cardiotoxicity of compounds and kits useful for the same.
    Type: Grant
    Filed: February 26, 1993
    Date of Patent: February 18, 1997
    Assignee: The Dupont Merck Pharmaceutical Company
    Inventors: Paul D. Crane, Cesare Orlandi