Abstract: A mold assembly includes a mold base plate and a mold. The mold base plate has a bottom plate located in a recess. The mold can be inserted into and removed from the recess and is located on top of the bottom plate. The mold has a first section that is separable from a second section.

Abstract: A mold apparatus includes a container, a temperature control device, a distribution manifold, a plurality of dispensers, a mold, a bottom plate for the mold, and a vacuum chamber. The temperature control device at least partially surrounds the container. The distribution manifold is located downstream from the container. The plurality of dispensers are coupled to the distribution manifold. The mold has a plurality of cavities for receiving a mixture from the plurality of dispensers. The bottom plate is located on a bottom surface of the mold. The vacuum chamber keeps the container, distribution manifold, plurality of dispensers and mold in a vacuum. A drug and compound mixture are brought to a temperature other than room temperature and dispensed into the mold under a vacuum to form pellets.

Abstract: A charging base for a battery-operated device has a port with a plurality of contacts and a charging connection. Testing circuitry is coupled to the plurality of contacts, and charging circuitry facilitates the charging connection. A housing at least partially encloses the testing circuitry and the charging circuitry.

Abstract: An ophthalmic injection system has a tip segment attachable to and removable from a limited reuse assembly. The tip segment has a dispensing chamber housing, a plunger, a needle, a temperature control device, a thermal sensor, and a first housing at least partially enclosing the dispensing chamber housing, the temperature control device and the plunger. The limited reuse assembly has an actuator with a shaft, a power source for providing power to the actuator, a controller for controlling the actuator, a mechanical linkage interface, and a second housing at least partially enclosing the power source, the controller, and the actuator. The mechanical linkage interface is coupled to the actuator shaft and has a mating surface on one end. The substance is injected after the temperature of the substance is altered.

Abstract: A disposable injection device includes a dispensing chamber, a plunger, a fuse in series with a light, and a housing. The dispensing chamber has an inner surface and an outer surface. The inner surface defines a cavity for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber, is capable of sliding in the cavity of the dispensing chamber, and is fluidly sealed to the inner surface of the dispensing chamber. The housing at least partially encloses the dispensing chamber and the plunger. After the substance has been delivered from the dispensing chamber, the fuse is blown causing the light to go out and disabling the device.

Abstract: An ophthalmic injection system is disclosed. The system has a dispensing member, a plunger, an actuation chamber, a lock mechanism, a lock stop, a port, a source of pressurized gas, and a shaft. The lock mechanism travels in the actuation chamber in an axial direction toward and away from a distal end of the dispensing member. The lock stop is located on the inner surface of the actuation chamber. The lock stop is engageable with the lock mechanism such that when the lock mechanism travels in the axial direction toward the distal end of the dispensing member to a first position located on a distal side of the lock stop, the lock mechanism cannot travel in a reverse direction away from the distal end of the dispensing member to a location on a proximal side of the lock stop.

Abstract: An ophthalmic injection device has a dispensing chamber housing, a plunger, an actuator for driving the plunger, a temperature control device, and a temperature release mechanism. The dispensing chamber housing has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The temperature control device at least partially surrounds the dispensing chamber housing and is capable of altering the temperature of the substance in the dispensing chamber. The temperature release mechanism is in a locked position when the substance is outside the proper temperature range and an unlocked position when the substance is in the proper temperature range.

Abstract: A disposable drug delivery device has a dispensing needle, a plunger, a spring, a shaft, and a lock mechanism. The plunger is engaged with the inner surface of the dispensing needle, is capable of sliding in the cavity of the dispensing needle, and is fluidly sealed to the inner surface of the dispensing needle. The spring is connected to the plunger via a shaft. The lock mechanism holds the shaft in a first position such that the spring is in a compressed state. When the lock mechanism releases the shaft, the spring extends providing a force that moves the shaft and connected plunger in a direction toward the tapered end of the dispensing needle thereby expelling the drug from the dispensing needle into an eye. The spring also provides a retaining force so that the plunger is retained in an extended position against the tapered end of the dispensing needle.

Abstract: A method is disclosed for delivering a quantity of a substance into an eye. By applying compressed gas into an actuation chamber, a separating member connected to a lock mechanism and a plunger is displaced. The plunger displaces the quantity of the substance from a dispensing member and into an eye. The plunger is retained in an extended position so that the quantity of the substance is not retracted back into the dispensing member when the dispensing member is removed from the eye.

Abstract: A disposable injection device has a dispensing chamber housing and a plunger. The dispensing chamber housing has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The plunger has a plunger interface. The plunger interface mates with a mating surface on a mechanical linkage interface such that force is transferred from the mechanical linkage interface to the plunger along a first direction towards the plunger when the plunger interface is in contact with the mating surface of the mechanical linkage interface, and force is not substantially transferred from the mechanical linkage interface to the plunger along a second direction away from the plunger.

Abstract: An injection device assembly includes a dispensing chamber housing and a plunger. The dispensing chamber housing is coupled to a needle. The dispensing chamber housing has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. A dosage of a substance is cast into the dispensing chamber housing or cast onto a plunger that is inserted into the dispensing chamber housing.

Abstract: A method of injecting a substance into an eye is disclosed. A connection between a disposable tip segment and a limited reuse assembly is recognized. A temperature control device is activated to alter the temperature of a substance contained in a dispensing chamber. Dosage information is read. In response to the dosage information, a mechanical linkage interface is advanced to advance a plunger to expel the substance from the dispensing chamber. The mechanical linkage interface is retracted without substantially retracting the plunger to prevent reflux of the substance. Reuse of the disposable tip segment is prevented. The removal of the disposable tip segment from the limited reuse assembly is recognized.

Abstract: An injection device includes a dispensing chamber, a plunger, a controller, a memory device resistant to sterilization, and a housing at least partially enclosing the dispensing chamber and the plunger. The dispensing chamber has an inner surface and an outer surface. The inner surface defines a cavity for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber, is capable of sliding in the cavity of the dispensing chamber, and is fluidly sealed to the inner surface of the dispensing chamber. The controller controls the operation of the injection device. The controller reads dosage data from the memory device and operates the injection device to deliver a dosage corresponding to the dosage data.

Abstract: An ophthalmic injection device has a dispensing chamber housing, a plunger, a needle fluidly coupled to a dispensing chamber, a temperature control device, a power source for providing power to the temperature control device, a controller for controlling the temperature control device, and a mechanical linkage mechanism. The interior surface of the dispensing chamber housing partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. A plunger shaft is coupled to the plunger. The temperature control device can alter the temperature of the substance contained therein. The mechanical linkage mechanism has at least two pivots and at least two shafts and transfers force from a lever to the plunger.