Patents by Inventor Cesira Galeotti
Cesira Galeotti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9932374Abstract: The invention provides methods, proteins, nucleic acids and antibodies for preventing or treating a C. difficile infection in a mammal.Type: GrantFiled: September 19, 2013Date of Patent: April 3, 2018Assignee: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Cesira Galeotti, Rosanna Leuzzi, Mariagrazia Pizza, Maria Scarselli, Meera Unnikrishnan, Manuele Martinelli
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Publication number: 20170080077Abstract: Alternative and improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae are disclosed. These approaches typically affect the level of expression, the ease of purification, the cellular localization, and/or the immunological properties of the expressed protein.Type: ApplicationFiled: December 2, 2016Publication date: March 23, 2017Applicant: GlaxoSmithKline Biologicals SAInventors: Maria ARICÒ, Maurizio COMANDUCCI, Cesira GALEOTTI, Vega MASIGNANI, Marzia Monica GIULIANI, Mariagrazia PIZZA
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Publication number: 20170080076Abstract: Alternative and improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae are disclosed. These approaches typically affect the level of expression, the ease of purification, the cellular localization, and/or the immunological properties of the expressed protein.Type: ApplicationFiled: December 2, 2016Publication date: March 23, 2017Applicant: GlaxoSmithKline Biologicals SAInventors: Maria ARICÒ, Maurizio COMANDUCCI, Cesira GALEOTTI, Vega MASIGNANI, Marzia Monica GIULIANI, Mariagrazia PIZZA
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Publication number: 20160051658Abstract: This invention provides, among other things, proteins, polypeptides, and fragments thereof, derived from the bacteria Neisseria meningitidis B. Also provided are nucleic acids encoding for such proteins, polypeptides, and/or fragments, as well as nucleic acids complementary thereto e.g., antisense nucleic acids). Additionally, this invention provides antibodies which bind to the proteins, polypeptides, and/or fragments. This invention further provides expression vectors useful for making the proteins, polypeptides, and/or fragments, as well as host cells transformed with such vectors. This invention also provides compositions of the proteins, polypeptides, fragments, and/or nucleic acids, for use as vaccines, diagnostic reagents, immunogenic compositions, and the like. Methods of making the compositions and methods of treatment with the compositions are also provided. This invention also provides methods of detecting the proteins, polypeptides, fragments, and/or nucleic acids.Type: ApplicationFiled: June 25, 2015Publication date: February 25, 2016Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Cesira GALEOTTI, Guido GRANDI, Vega MASIGNANI, Marirosa MORA, Mariagrazia PIZZA, Rino RAPPUOLI, Giulio RATTI, Vincenzo SCARLATO, Maria SCARSELLI
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Patent number: 9266929Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: GrantFiled: August 1, 2014Date of Patent: February 23, 2016Assignee: GlaxoSmithKline Biologicals SAInventors: Claire Fraser, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
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Patent number: 9267163Abstract: Two or more Neisserial proteins (e.g. A and B) are expressed as a single hybrid protein which can be represented simply by the formula NH2-A-B—COOH.Type: GrantFiled: February 25, 2005Date of Patent: February 23, 2016Assignee: GlaxoSmithKline Biologicals SAInventors: Maria Aricò, Maurizio Comanducci, Cesira Galeotti, Vega Masignani, Marzia Monica Giuliani, Mariagrazia Pizza
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Publication number: 20160030545Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: ApplicationFiled: July 21, 2015Publication date: February 4, 2016Applicant: GLAXOSMITHKLINE BIOLOGICALS SAInventors: Claire FRASER, Cesira GALEOTTI, Guido GRANDI, Erin HICKEY, Vega MASIGNANI, Marirosa MORA, Jeremy PETERSEN, Mariagrazia PIZZA, Rino RAPPUOLI, Giulio RATTI, Vincenzo SCARLATO, Maria SCARSELLI, Herve TETTELIN, J. Craig VENTER
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Patent number: 9249198Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: GrantFiled: August 1, 2014Date of Patent: February 2, 2016Assignee: GlaxoSmithKline Biologicals SAInventors: Claire Fraser, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
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Patent number: 9249196Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: GrantFiled: January 26, 2012Date of Patent: February 2, 2016Assignee: GlaxoSmithKline Biologicals SAInventors: Claire Fraser, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
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Publication number: 20150315248Abstract: The invention provides methods, proteins, nucleic acids and antibodies for preventing or treating a C. difficile infection in a mammal.Type: ApplicationFiled: September 19, 2013Publication date: November 5, 2015Inventors: Cesira GALEOTTI, Rosanna LEUZZI, Mariagrazia PIZZA, Maria SCARSELLI, Meera UNNIKRISHNAN, Manuele MARTINELLI
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Patent number: 9150898Abstract: Alternative and improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae are disclosed. These approaches typically affect the level of expression, the ease of purification, the cellular localization, and/or the immunological properties of the expressed protein.Type: GrantFiled: July 31, 2014Date of Patent: October 6, 2015Assignee: GlaxoSmithKline Biologicals SAInventors: Maria Aricò, Maurizio Comanducci, Cesira Galeotti, Vega Masignani, Marzia Monica Giuliani, Mariagrazia Pizza
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Patent number: 9139621Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: GrantFiled: March 23, 2011Date of Patent: September 22, 2015Assignee: GlaxoSmithKline Biologicals SAInventors: Claire Fraser, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
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Patent number: 9067987Abstract: This invention provides, among other things, proteins, polypeptides, and fragments thereof, derived from the bacteria Neisseria meningitidis B. Also provided are nucleic acids encoding for such proteins, polypeptides, and/or fragments, as well as nucleic acids complementary thereto e.g., antisense nucleic acids). Additionally, this invention provides antibodies which bind to the proteins, polypeptides, and/or fragments. This invention further provides expression vectors useful for making the proteins, polypeptides, and/or fragments, as well as host cells transformed with such vectors. This invention also provides compositions of the proteins, polypeptides, fragments, and/or nucleic acids, for use as vaccines, diagnostic reagents, immunogenic compositions, and the like. Methods of making the compositions and methods of treatment with the compositions are also provided. This invention also provides methods of detecting the proteins, polypeptides, fragments, and/or nucleic acids.Type: GrantFiled: February 24, 2012Date of Patent: June 30, 2015Assignee: GlaxoSmithKline Biologicals SAInventors: Cesira Galeotti, Guido Grandi, Vega Masignani, Marirosa Mora, Mariagrazia Pizza, Rino Rappuoli, Guilio Ratti, Vincenzo Scarlato, Maria Scarselli
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Publication number: 20150086582Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: ApplicationFiled: August 1, 2014Publication date: March 26, 2015Inventors: Claire FRASER, Cesira GALEOTTI, Guido GRANDI, Erin HICKEY, Vega MASIGNANI, Marirosa MORA, Jeremy PETERSEN, Mariagrazia PIZZA, Rino RAPPUOLI, Giulio RATTI, Vincenzo SCARLATO, Maria SCARSELLI, Herve TETTELIN, J. Craig VENTER
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Publication number: 20150079124Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: ApplicationFiled: August 1, 2014Publication date: March 19, 2015Inventors: Claire FRASER, Cesira GALEOTTI, Guido GRANDI, Erin HICKEY, Vega MASIGNANI, Marirosa MORA, Jeremy PETERSEN, Mariagrazia PIZZA, Rino RAPPUOLI, Giulio RATTI, Vincenzo SCARLATO, Maria SCARSELLI, Herve TETTELIN, J. Craig VENTER
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Publication number: 20140363462Abstract: Alternative and improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae are disclosed. These approaches typically affect the level of expression, the ease of purification, the cellular localization, and/or the immunological properties of the expressed protein.Type: ApplicationFiled: July 31, 2014Publication date: December 11, 2014Inventors: Maria ARICÒ, Maurizio COMANDUCCI, Cesira GALEOTTI, Vega MASIGNANI, Marzia Monica GIULIANI, Mariagrazia PIZZA
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Publication number: 20140294885Abstract: Alternative and improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae are disclosed. These approaches typically affect the level of expression, the ease of purification, the cellular localization, and/or the immunological properties of the expressed protein.Type: ApplicationFiled: April 3, 2014Publication date: October 2, 2014Applicant: NOVARTIS AGInventors: Maria Beatrice ARICO, Maurizio COMANDUCCI, Cesira GALEOTTI, Vega MASIGNANI, Marzia Monica GIULIANI, Mariagrazia PIZZA
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Patent number: 8734812Abstract: This invention provides, among other things, proteins, polypeptides, and fragments thereof, derived from the bacteria Neisseria meningitidis B. Also provided are nucleic acids encoding for such proteins, polypeptides, and/or fragments, as well as nucleic acids complementary thereto (e.g., antisense nucleic acids). Additionally, this invention provides antibodies which bind to the proteins, polypeptides, and/or fragments. This invention further provides expression vectors useful for making the proteins, polypeptides, and/or fragments, as well as host cells transformed with such vectors. This invention also provides compositions of the proteins, polypeptides, fragments, and/or nucleic acids, for use as vaccines, diagnostic reagents, immunogenic compositions, and the like. Methods of making the compositions and methods of treatment with the compositions are also provided. This invention also provides methods of detecting the proteins, polypeptides, fragments, and/or nucleic acids.Type: GrantFiled: October 30, 2000Date of Patent: May 27, 2014Assignee: Novartis AGInventors: Cesira Galeotti, Guido Grandi, Vega Masignani, Mariarosa Mora, Mariagrazia Pizza, Rino Rappuoli, Guilio Ratti, Vincenzo Scarlato, Maria Scarselli
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Patent number: 8703914Abstract: Alternative and improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and Neisseria gonorrhoeae. These approaches typically affect the level of expression, the ease of purification, the cellular localization, and/or the immunological properties of the expressed protein.Type: GrantFiled: December 29, 2011Date of Patent: April 22, 2014Assignee: Novartis AGInventors: Maria Beatrice Arico, Maurizio Comanducci, Cesira Galeotti, Vega Masignani, Marizia Monica Guiliani, Mariagrazia Pizza
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Patent number: 8524251Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: GrantFiled: January 26, 2012Date of Patent: September 3, 2013Assignees: J. Craig Venter Institute, Inc., Novartis AGInventors: Claire Fraser, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter