Patents by Inventor Cha-Soon Kim

Cha-Soon Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression and secretion vector for human interferon alpha and process for producing human interferon alpha by employing same
    Patent number: 7052867
    Abstract: Disclosed in this invention are an expression vector for the secretive production of human interferon alpha (hIFN?) comprising a polynucleotide encoding a modified E. coli thermostable enterotoxin II signal sequence and a polynucleotide encoding hIFN? ligated to the 3?-end thereof; a microorganism transformed with the expression vector; and a process for secretively producing human interferon by culturing the microorganism, the process being capable of secreting a soluble form of active hIFN?, which does not contain an additional methionine residue at its N-terminal, into the periplasm of an E. coli cell.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: May 30, 2006
    Assignee: Hanmi Pharm. Co., Ltd.
    Inventors: Se-Chang Kwon, Sung-Youb Jung, Ki-Doo Choi, Cha-Soon Kim, Sung-Min Bae, Gwan-Sun Lee
  • Expression and secretion vector for human interferon alpha and process for producing human interferon alpha by employing same
    Publication number: 20040151695
    Abstract: Disclosed in this invention are: an expression vector for the secretive production of human interferon alpha (hIFN&agr;) comprising a polynucleotide encoding a modified E. coli thermostable enterotoxin II signal sequence and a polynucleotide encoding hIFN&agr;) ligated to the 3′-end thereof; a microorganism transformed with the expression vector, and a process for secretively producing human interferon by culturing the microorganism, said process being capable of secreting a soluble form of active hIFN&agr;), which does not contain an additional methionine residue at its N-terminal, into the periplasm of an E coli cell.
    Type: Application
    Filed: July 18, 2002
    Publication date: August 5, 2004
    Inventors: Se-Chang Chang Kwon, Sung-Youb Jung, Ki-Doo Choi, Cha-Soon Kim, Sung-Min Bae, Gwan-Sun Lee