Patents by Inventor Chad Alan Van Huis

Chad Alan Van Huis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20230295119
    Abstract: Compounds having the structure of Formula (I) or pharmaceutically acceptable isomers, racemates, hydrates, solvates or salts thereof, where A, R1, R2a, R2b, R2c and R3 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFN? by acting on TYK2 to cause signal transduction inhibition, as well as to pharmaceutical compositions containing the same and to methods of their use and preparation.
    Type: Application
    Filed: April 14, 2021
    Publication date: September 21, 2023
    Inventors: Craig Alan Coburn, Chad Alan Van Huis, Thomas Daniel Aicher
  • Benzodiazepinone compounds and methods of treatment using same
    Patent number: 8673897
    Abstract: The invention provides 1,4-benzodiazepinone compounds, pharmaceutical compositions, and methods of treating autoimmune disorders, chronic inflammatory disorders, and hyperproliferative disorders. For example, the 1,4-benzodiazepinone compounds and pharmaceutical compositions are contemplated to be useful for treating rheumatoid arthritis, graft-versus-host disease, inflammatory bowel disease, and the like.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: March 18, 2014
    Assignee: The Regents of the University of Michigan
    Inventors: Gary D. Glick, Alexander Ross Hurd, Chad Alan Van Huis
  • 1,4-benzodiazepinone compounds and their use in treating cancer
    Patent number: 8604023
    Abstract: The invention provides a family of 1,4-benzodiazepinone compounds and methods for their use as therapeutic agents in treating cancer. Pharmaceutical compositions and methods of making the 1,4-benzodiazepinone compounds are provided.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: December 10, 2013
    Assignee: The Regents of the University of Michigan
    Inventors: Gary D. Glick, Clarke Bentley Taylor, Peter Laurence Toogood, Chad Alan Van Huis
  • BENZODIAZEPINONE COMPOUNDS AND METHODS OF TREATMENT USING SAME
    Publication number: 20120232067
    Abstract: The invention provides 1,4-benzodiazepinone compounds, pharmaceutical compositions, and methods of treating autoimmune disorders, chronic inflammatory disorders, and hyperproliferative disorders. For example, the 1,4-benzodiazepinone compounds and pharmaceutical compositions are contemplated to be useful for treating rheumatoid arthritis, graft-versus-host disease, inflammatory bowel disease, and the like.
    Type: Application
    Filed: September 17, 2010
    Publication date: September 13, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Gary D. Glick, Alexander Ross Hurd, Chad Alan Van Huis
  • 1,4-BENZODIAZEPINONE COMPOUNDS AND THEIR USE IN TREATING CANCER
    Publication number: 20120094982
    Abstract: The invention provides a family of 1,4-benzodiazepinone compounds and methods for their use as therapeutic agents in treating cancer. Pharmaceutical compositions and methods of making the 1,4-benzodiazepinone compounds are provided.
    Type: Application
    Filed: April 16, 2010
    Publication date: April 19, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Gary D. Glick, Clarke Bentley Taylor, Peter Laurence Toogood, Chad Alan Van Huis
  • INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE
    Publication number: 20090221546
    Abstract: Compounds useful as intermediates for synthesis of compounds of Formula (1): wherein A, B, C, G, and W1 have any of the values defined in the specification.
    Type: Application
    Filed: June 16, 2008
    Publication date: September 3, 2009
    Inventors: Christopher Franklin Bigge, Agustin Casimiro-Garcia, Danette Andrea Dudley, Jeremy John Edmunds, Kevin James Filipski, Jeffrey Thomas Kohrt, Chad Alan Van Huis
  • Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade
    Publication number: 20080287674
    Abstract: Compounds useful as intermediates for synthesis of compounds of Formula (I): wherein A, B, C, G, and W1 have any of the values defined in the specification.
    Type: Application
    Filed: June 26, 2008
    Publication date: November 20, 2008
    Inventors: Christopher Franklin Bigge, Agustin Casimiro-Garcia, Danette Andrea Dudley, Jeremy John Edmunds, Kevin James Filipski, Jeffrey Thomas Kohrt, Chad Alan Van Huis
  • Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
    Patent number: 7407974
    Abstract: The present invention provides compounds of Formula (I): wherein A, B, C, G, and W1 have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful to treat thrombotic disorders. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula I, processes for preparing compounds of Formula I, and intermediates useful for preparing compounds of Formula I.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: August 5, 2008
    Assignee: Pfizer Inc.
    Inventors: Christopher Franklin Bigge, Agustin Casimiro-Garcia, Danette Andrea Dudley, Jeremy John Edmunds, Kevin James Filipski, Jeffrey Thomas Kohrt, Chad Alan Van Huis
  • Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
    Patent number: 7030141
    Abstract: The present invention provides compounds of Formula (I): wherein A, B, C, G, and W1 have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful to treat thrombotic disorders. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula I, processes for preparing compounds of Formula I, and intermediates useful for preparing compounds of Formula I.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: April 18, 2006
    Inventors: Christopher Franklin Bigge, Agustin Casimiro-Garcia, Danette Andrea Dudley, Jeremy John Edmunds, Kevin James Filipski, Jeffrey Thomas Kohrt, Chad Alan Van Huis
  • Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
    Publication number: 20030162787
    Abstract: The present invention provides compounds of Formula (I): 1
    Type: Application
    Filed: October 23, 2002
    Publication date: August 28, 2003
    Inventors: Christopher Franklin Bigge, Agustin Casimiro-Garcia, Danette Andrea Dudley, Jeremy John Edmunds, Kevin James Filipski, Jeffrey Thomas Kohrt, Chad Alan Van Huis