Abstract: The present invention provides comprehensive compositions for treating problems associated with hair graying and balding via the incorporation of: (i) the cell growth factor of HSCF to induce the migration of melanocyte stem cells and keratinocyte stem cells and then to increase the growth of melanocytes and keratinocytes in hair follicles, (ii) a formula of amino acids and vitamins to provide the nutritional factors for hair growth and pigmentation, and (iii) minoxidil to enhance the function of HSCF on hair re-growth. The compositions comprising at least one of (i), (ii) or (iii) are administered on skin and/or scalp through liposome in the follicular delivery systems, including penetration enhancers and suitable carrier bases. The compositions packaged in liposome in the follicular delivery systems in this invention has been proven to reach the dermis from the skin surface within 15-30 min.

Abstract: A method, medical device (10) and test kit for capacitation of sperm for fertilizing eggs in vitro or in vivo, is described. The sperm is particularly from lower mammals, such as domestic animals and wild animals to be bred in captivity. The capacitated sperm is also useful in research relating to the nature of capacitation of sperm following modification of the head of the sperm upon capacitation.