Abstract: The disclosed subject matter provides systems and methods for identifying bioactivities of biopolymers from sequence data of the biopolymers. The disclosed system can include a processor configured to receive the input data and a storage medium including instructions operable when executed by the processors. The instructions can cause the system to obtain the input data and generate an evaluative model configured to acquire a biophysical model parameter, a model interaction parameter, a count table parameter, or combinations thereof utilizing the input data. The evaluative model can be configured to simultaneously use multiple biophysical models to represent one or more sequence recognition modes of the biopolymers, evaluate the biopolymers using the evaluative model, and generate a value using the evaluating model that corresponds to the bioactivity of each biopolymer.

Abstract: Techniques for hyperspectral imaging, including a device for hyperspectral imaging including at least one tunable interferometer including a thin layer of material disposed between two or more broadband mirrors. Electrodes placed on either side of the tunable interferometer can be coupled to a voltage control circuit, and upon application of a voltage across the tunable interferometer, the distance between the mirrors can be modulated by physically altering the dimensions of the thin layer of material, which can uniformly load the broadband mirrors. Physically altering the dimensions of the thin layer of material can include one or more of deformation of a soft material, piezostrictrive actuation of a piezostrictrive material, or electrostrictive actuation of an electrostrictive material.

Abstract: Techniques for hyperspectral imaging, including a device for hyperspectral imaging including at least one tunable interferometer including a thin layer of material disposed between two or more broadband mirrors. Electrodes placed on either side of the tunable interferometer can be coupled to a voltage control circuit, and upon application of a voltage across the tunable interferometer, the distance between the mirrors can be modulated by physically altering the dimensions of the thin layer of material, which can uniformly load the broadband mirrors. Physically altering the dimensions of the thin layer of material can include one or more of deformation of a soft material, piezostrictrive actuation of a piezostrictrive material, or electrostrictive actuation of an electrostrictive material.

Abstract: Systems for untethered sensing and recording of activity of one or more electrically excitable cells in a target region includes at least one untethered probe. Each untethered probe includes at least one signal detector, configured to electrically couple to the target region, measure the activity of the one or more electrically excitable cells, and produce an electrical signal in response to the activity of the one or more electrically excitable cells, and at least one light source, electrically coupled to the at least one signal detector, to receive the electrical signal and emit a light signal representing the activity of the one or more electrically excitable cells. Methods for untethered sensing and recording of activity of one or more electrically excitable cells in a target region are also provided.