Patents by Inventor Chamberlain Obialo

Chamberlain Obialo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
    Patent number: 11874283
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: January 16, 2024
    Assignee: Morehouse School of Medicine
    Inventors: Gale W. Newman, James W. Lillard, Jr., Chamberlain Obialo
  • METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES
    Publication number: 20220260590
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Application
    Filed: May 10, 2022
    Publication date: August 18, 2022
    Inventors: Gale W. NEWMAN, James W. LILLARD, Jr., Chamberlain OBIALO
  • Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
    Patent number: 11372005
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: June 28, 2022
    Assignee: Morehouse School of Medicine
    Inventors: Gale W. Newman, James W. Lillard, Jr., Chamberlain Obialo
  • METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES
    Publication number: 20210247406
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Application
    Filed: April 29, 2021
    Publication date: August 12, 2021
    Inventors: Gale W. NEWMAN, James W. Lillard, JR., Chamberlain Obialo
  • METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES
    Publication number: 20210072261
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Application
    Filed: November 10, 2020
    Publication date: March 11, 2021
    Inventors: Gale W. NEWMAN, James W. LILLARD, Jr., Chamberlain OBIALO
  • Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
    Patent number: 10866249
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: December 15, 2020
    Assignee: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. Newman, Barbara A. Jacob-Mungin, Chamberlain Obialo
  • Detection of HIV-related proteins in urine
    Patent number: 10545149
    Abstract: A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HIV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: January 28, 2020
    Assignee: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. Newman, Mike Powell, Akins Doherty, Chamberlain Obialo, Claudette Mitchell-Ali, Khalid Bashir, Mafuz Khan
  • Detection of HIV-related proteins in urine
    Patent number: 9581596
    Abstract: A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HIV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: February 28, 2017
    Assignee: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. Newman, Mike Powell, Akins Doherty, Chamberlain Obialo
  • Detection of HIV-related proteins in urine
    Patent number: 9541554
    Abstract: A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HIV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed.
    Type: Grant
    Filed: January 11, 2012
    Date of Patent: January 10, 2017
    Assignee: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. Newman, Mike Powell, Akins Doherty, Chamberlain Obialo
  • Method and compositions for the treatment and detection of endothelin-1 related kidney diseases
    Patent number: 9255931
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: February 9, 2016
    Assignee: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale Newman, Barbara A. Jacob-Mungin, Chamberlain Obialo
  • METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES
    Publication number: 20150335703
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 26, 2015
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. NEWMAN, Barbara A. Jacob-Mungin, Chamberlain Obialo
  • METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES
    Publication number: 20130252898
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Application
    Filed: May 30, 2013
    Publication date: September 26, 2013
    Applicant: Morehouse School Of Medicine
    Inventors: Gale W. Newman, Barbara A. Jacob-Mungin, Chamberlain Obialo
  • DETECTION OF HIV-RELATED PROTEINS IN URINE
    Publication number: 20120214151
    Abstract: A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HIV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed.
    Type: Application
    Filed: January 11, 2012
    Publication date: August 23, 2012
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. Newman, Mike Powell, Akins Doherty, Chamberlain Obialo
  • DETECTION OF HIV-RELATED PROTEINS IN URINE
    Publication number: 20120208175
    Abstract: A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HIV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed.
    Type: Application
    Filed: January 11, 2012
    Publication date: August 16, 2012
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. Newman, Mike Powell, Akins Doherty, Chamberlain Obialo
  • METHOD AND COMPOSITIONS FOR THE TREATMENT AND DETECTION OF ENDOTHELIN-1 RELATED KIDNEY DISEASES
    Publication number: 20110319333
    Abstract: The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
    Type: Application
    Filed: June 16, 2011
    Publication date: December 29, 2011
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. NEWMAN, Barbara A. JACOB-MUNGIN, Chamberlain OBIALO
  • DETECTION OF HIV-RELATED PROTEINS IN URINE
    Publication number: 20100086956
    Abstract: A method for detecting HIV infection in a mammal is disclosed. The method contains the steps of isolating exosomes from a urine sample of a mammal and detecting the presence of HIV-specific biomarker in said isolated exosomes. A method for diagnosing a mammal with an HIV-associated disease, in particular, HIV-associated nephropathy is also disclosed.
    Type: Application
    Filed: October 2, 2009
    Publication date: April 8, 2010
    Applicant: MOREHOUSE SCHOOL OF MEDICINE
    Inventors: Gale W. Newman, Mike Powell, Akins Doherty, Chamberlain Obialo, Claudette Mitchell-Ali, Khalid Bashir, Mafuz Khan