Patents by Inventor Chamini Karunaratne

Chamini Karunaratne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PXR agonists and uses thereof for gut barrier dysfunction treatment and prevention
    Patent number: 11724998
    Abstract: Small molecule agonists of the pregnane X receptor (PXR), compositions and methods are disclosed for treating or preventing gut barrier dysfunction, an illness associated with gut barrier dysfunction, toxic or inflammatory injury to intestines, or leaky intestinal (gut) syndrome in a subject.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: August 15, 2023
    Assignees: Albert Einstein College of Medicine, Drexel University, Palacky University Olomouc
    Inventors: Sridhar Mani, Felix Kopp, Zdenek Dvorak, Sandhya Kortagere, Chamini Karunaratne
  • PXR AGONISTS AND USES THEREOF FOR GUT BARRIER DYSFUNCTION TREATMENT AND PREVENTION
    Publication number: 20190367475
    Abstract: Small molecule agonists of the pregnane X receptor (PXR), compositions and methods are disclosed for treating or preventing gut barrier dysfunction, an illness associated with gut barrier dysfunction, toxic or inflammatory injury to intestines, or leaky intestinal (gut) syndrome in a subject.
    Type: Application
    Filed: January 18, 2018
    Publication date: December 5, 2019
    Inventors: Sridhar Mani, Felix Kopp, Zdenek Dvorak, Sandhya Kortagere, Chamini Karunaratne