Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.

Abstract: A rotary buckle comprises a female buckling element and a male buckling element. The female buckling element comprises an opening and a bucking portion, wherein a side opposite to the opening comprises a receiving chamber. The male buckle element comprises a fitting portion for fitting into the opening of the female buckling element and a latching portion for buckling position into the buckling portion of the female buckling element, wherein a side opposite to the fitting portion comprises a receiving chamber for receiving a knitted belt, and wherein a track is disposed at a side opposite to the opening of said female buckling element along which a directing element of the receiving chamber of the female buckle can be rotated.

Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.

Abstract: Compounds of formula I: wherein R1, R2, R4, R10, R11, and Q are as defined herein, and their pharmaceutically acceptable salts, are useful in the prevention or treatment of HIV infections.

Abstract: Apparatus and method for controlling an operation of a blower fan are provided. In the apparatus and method, a temperature of an evaporator is measured, and an amount of cool air remaining in the evaporator is computed from the measured temperature of the evaporator such that the cool air of the evaporator can be sufficiently used. According to the present invention, a use efficiency of the refrigerator can be further enhanced.

Abstract: Provided is a radiating apparatus of a built-in refrigerator that can improve heat radiation in a machine room of the refrigerator installed in a built-in cabinet. The radiating apparatus includes: a refrigerator body installed in a built-in cabinet; a machine room disposed at a rear lower side of the refrigerator body; a compressor installed at one side of the machine room; a condenser and a blower fan installed at the other side of the machine room; and an airflow guide member installed between the blower fan and the condenser, for guiding a suction of an external air toward the other side of the machine room and guiding a discharge of an air that has exchanged heat in the other side of the machine room.

Abstract: Disclosed is an icemaker for a refrigerator includes an ice mold for receiving water and freezing the water to ice, an ejector pivotally installed on the ice mold to eject the ice out of the ice mold, a motor for operating the ejector, a heater body disposed enclosing the ice mold to separate the ice from an inner surface of the ice mold by uniformly heating the ice mold, and a heating coil for applying induced electromotive power to the heater body, thereby allowing the heater body to generate heat.

Abstract: A radiating apparatus of a built-in refrigerator includes an airflow guide that separates a condenser from a blower fan in order to prevent a cool air and a hot air from mixing together, thereby increasing an efficiency of the built-in refrigerator.

Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating Flaviviridae viral infection.

Abstract: The present invention provides novel compounds represented by formula I: or pharmaceutically acceptable salts thereof useful for treating flaviviridae viral infection.

Abstract: Novel compounds represented by formula I: wherein Y, Z, X, W, R1, R2 and R3 are as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity and the treatment or prevention of diseases associated therewith.

Abstract: Compounds of formula I wherein R1, R2, R3, R4 and R5 are as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity.

Abstract: Compounds represented by formula: wherein X, Y and Z are as defined herein, pharmaceutically acceptable salts thereof, and related compounds, are suitable for use in treating or preventing a Flaviviridae viral infection in a host.

Abstract: Compounds represented by formula I: 1

Abstract: The present invention provides novel compounds represented by formula I: 1

Abstract: the present invention provides novel compounds represented by formula I: 1

Abstract: The present invention provides novel compounds represented by formula I: 1

Abstract: The present invention relates to heterocyclic compounds having antiviral activity.

Abstract: Nucleotide analogues having the general formula (I) and pharmaceutically acceptable derivatives: wherein n is 0 or an integer; X is O or S, CH2, CH-halogen, CH—N3, or C═CH2; Q and U are independently selected from: O, S, and CH(Ra) wherein Ra is hydrogen, OH, halogen, N3 ,NH2, SH, carboxyl, C1-6 alkyl or Ra is CH2(Rb) wherein Rb is hydrogen, OH, SH, NH2, C1-6 alkyl or carboxyl; or both Q and U are CH when Q and U are linked by a double bond; Z is selected from: O, a C1-6 alkoxy, a C1-6 thioalkyl, a C1-6 aminoalkyl, (CH2)m wherein m is 0 or an integer, and N(Rc)2 wherein both Rc are independently hydrogen or a C1-6 alkyl; and R2 is a purine or pyrimidine base or an analogue or derivative thereof. Members of this series of analogues possess anti-viral activity.

Abstract: Nucleotide analogues having the general formula (I) and pharmaceutically acceptable derivatives: ##STR1## wherein n is 0 or an integer; X is O or S, CH.sub.2, CH--halogen, CH--N.sub.3, or C.dbd.CH.sub.2 ;Q and U are independently selected from: O, S, and CH(R.sub.a) wherein R.sub.a is hydrogen, OH, halogen, N.sub.3, NH.sub.2, SH, carboxyl, C.sub.1-6 alkyl or R.sub.a is CH.sub.2 (R.sub.b) wherein R.sub.b is hydrogen, OH, SH, NH.sub.2, C.sub.1-6 alkyl or carboxyl; or both Q and U are CH when Q and U are linked by a double bond;Z is selected from: O, a C.sub.1-6 alkoxy, a C.sub.1-6 thioalkyl, a C.sub.1-6 aminoalkyl, (CH.sub.2).sub.m wherein m is 0 or an integer, and N(R.sub.c).sub.2 wherein both R.sub.c are independently hydrogen or a C.sub.1-6 alkyl; andR2 is a purine or pyrimidine base or an analogue or derivative thereof. Members of this series of analogues possess anti-viral activity.