Abstract: A lipid nanoparticles manufacturing chip includes a first raw material supply flow path, a second raw material supply flow path, and a mixer portion connected to the first raw material supply flow path and the second raw material supply flow path and configured for mixing a first raw material supplied through the first raw material supply flow path and a second raw material supplied through the second raw material supply flow path. The mixer portion includes a first stabilizing unit, and a first mixing unit connected to the first stabilizing unit and configured for mixing the first raw material and the second raw material with each other. Mixing of the first raw material and the second raw material is performed more in the first mixing unit than in the first stabilizing unit.

Abstract: A solvent-removing apparatus according to an embodiment includes a tank body accommodating an emulsion including first source material in a continuous phase and second source material in a dispersed phase, a fluid supply unit for supplying fluid into the tank body to cause the emulsion to circulate, and a discharge unit for discharging the gas in the tank body to the outside.

Abstract: The present disclosure relates to a method for manufacturing lipid nanoparticles and an apparatus for manufacturing the same, which are capable of increasing a production yield in a subsequent eradication filtration process and the like by not requiring a separate process for sorting the manufactured lipid nanoparticles. In addition, by deviating from an existing optimal drug and lipid ratio, a content of ionizable lipid that causes a problem of toxicity when injected into the body may be lowered, and uniform-sized lipid nanoparticles may be manufactured.

Abstract: A solvent removing apparatus includes a container containing an emulsion comprising a first raw material of a continuous phase and a second raw material of a dispersed phase, an impeller rotating in the container to stir the emulsion, and a foam breaker spaced apart from the impeller on an upper portion of the impeller, positioned below a surface of the emulsion to be submerged in the emulsion when the emulsion is calm, and rotating to reduce foam generated during stirring of the emulsion.

Abstract: A system for producing a microsphere includes a first raw material storing to store a first raw material is stored, a second raw material storing part to store a second raw material including a solvent, a biodegradable polymer, and a drug, an emulsion generating part to continuously form an emulsion including the first raw material of a continuous phase and the second raw material of a dispersed phase, a first solvent extracting and removing part to accommodate the emulsion formed from the emulsion generating part, and extract and remove the solvent from the dispersed phase of the emulsion to form a microsphere, and a second solvent extracting and removing part spaced apart from the first solvent extracting and removing part, to accommodate the emulsion formed from the emulsion generating part, and extract and remove the solvent from the dispersed phase of the emulsion to form a microsphere.

Abstract: A solvent-removing apparatus according to an embodiment includes a tank body accommodating an emulsion including first source material in a continuous phase and second source material in a dispersed phase, a fluid supply unit for supplying fluid into the tank body to cause the emulsion to circulate, and a discharge unit for discharging the gas in the tank body to the outside.

Abstract: A lipid nanoparticles manufacturing chip includes a mixer unit for forming a mixed solution by mixing a first raw material containing an active ingredient and a second raw material containing a lipid, a dilution unit that is connected to the mixer unit and dilutes the mixed solution using a diluent solution to make a diluted mixed solution, and a concentration unit connected to the dilution unit and for obtaining a concentrated solution by concentrating lipid nanoparticles (LNP) from the diluted mixed solution.

Abstract: A microparticle producing system using microfluidics and a controlling method thereof, and specifically, to a microparticle producing system that may stably transport droplets produced using microfluidics without agglomeration or destruction, compared to the conventional art, and a method of controlling the microparticle producing system to transport the droplets more stably in the microparticle producing system. By the microparticle producing system and the controlling method thereof, which are disclosed herein, droplets produced by the microparticle producing system using microfluidics may be stably transported without agglomeration or destruction, resulting in more effective microparticle production.

Abstract: A solvent removing apparatus includes a container containing an emulsion comprising a first raw material of a continuous phase and a second raw material of a dispersed phase, an impeller rotating in the container to stir the emulsion, and a foam breaker spaced apart from the impeller on an upper portion of the impeller, positioned below a surface of the emulsion to be submerged in the emulsion when the emulsion is calm, and rotating to reduce foam generated during stirring of the emulsion.

Abstract: A microparticle producing system using microfluidics and a controlling method thereof, and specifically, to a microparticle producing system that may stably transport droplets produced using microfluidics without agglomeration or destruction, compared to the conventional art, and a method of controlling the microparticle producing system to transport the droplets more stably in the microparticle producing system. By the microparticle producing system and the controlling method thereof, which are disclosed herein, droplets produced by the microparticle producing system using microfluidics may be stably transported without agglomeration or destruction, resulting in more effective microparticle production.

Abstract: The present specification relates to a sphingosine-1-phosphate (S1P) analogue and a method of synthesizing the same. A novel S1P analogue disclosed by the present specification is highly water-soluble and highly stable due to an alkoxyamine group thereof. Thus, the novel S1P analogue is suitable for use in manufacturing an immunodiagnostic kit.

Abstract: A specimen containing unit according to one embodiment of the present invention relates to a structure for dipping a specimen into a reagent so as to react with the reagent, and the specimen containment unit comprises: a body portion rotatable by external force; an extension portion formed to be extended from one surface of the body portion at a predetermined length along a longitudinal direction; and a specimen containment portion provided to an end portion of the extension portion and including a containment hole formed to be penetrated while maintaining at a predetermined angle in the longitudinal direction so as to contain a specimen by a capillary phenomenon.