Abstract: Disclosed herein are an apparatus and method for classifying clothing attributes based on deep learning. The apparatus includes memory for storing at least one program and a processor for executing the program, wherein the program includes a first classification unit for outputting a first classification result for one or more attributes of clothing worn by a person included in an input image, a mask generation unit for outputting a mask tensor in which multiple mask layers respectively corresponding to principal part regions obtained by segmenting a body of the person included in the input image are stacked, a second classification unit for outputting a second classification result for the one or more attributes of the clothing by applying the mask tensor, and a final classification unit for determining and outputting a final classification result for the input image based on the first classification result and the second classification result.

Abstract: A method is provided for treating a patient with a disease. The method includes administration of a repeated cycle of alternation of a rapid depletion of L-ascorbic acid (LAA) and supplementation of a high dose of LAA, wherein the rapid depletion of LAA is achieved by blocking of LAA signal transduction and/or by blocking of LAA transporter to control growth of malignant cells in a body of the patient. Further, a pharmaceutical composition designed to perform at least one of: a blocking of a LAA signal transduction and/or a blocking of a LAA transporter is provided. The pharmaceutical composition may be used as a depletion means of LAA in a cyclic administration of the depletion of LAA followed by the high dose supplementation of LAA over a period of time.

Abstract: Artificial modulation of ascorbate level was investigated in mice capable of de novo synthesis of ascorbate. When mice were given exogenous ascorbate or its physiological precursor, L-gulono-?-lactone, the plasma level of ascorbate was elevated substantially but immediately returned to the basal levels. Comparably, the administration of ascorbate oxidase caused a rapid disappearance of plasma ascorbate but followed by an immediate restoration of ascorbate. These results indicate the difficulties encountered in the modulation of ascorbate level in the animal. However, the circulation life of the exogenous ascorbate oxidase in the animal was successfully extended by chemical modification with methoxypolyethylene glycol. The modified enzyme retained a full activity and exerted a remarkably prolonged depletion of plasma ascorbate compared with the native enzyme.