Abstract: A powder feeding device is disclosed. The powder feeding device according to an embodiment of the present disclosure can optimize a state of powder provided to a coater roll.

Abstract: A system of manufacturing an electrode is disclosed. The system includes a first drying portion drying a coating material coated on a coating substrate, and a second drying portion selectively drying at least a portion of the coating material that has passed through the first drying portion. According to an embodiment of the present disclosure, a uniform dryness degree of an electrode on which a drying process is completed may be maintained.

Abstract: The present disclosure relates to a novel thyroid nodule diagnostic biomarker and use thereof, and more specifically to an mRNA biomarker or a combination of mRNA biomarkers that are capable of diagnosing non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) among thyroid nodules with high accuracy and sensitivity compared to benign and malignant tumors. In the present disclosure, it was confirmed that the expression levels of OCLN, ZNF423, LYG1 and AQP5 are associated with the onset or aggravation of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Accordingly, the present disclosure provides OCLN, ZNF423, LYG1 and AQP5 genes as diagnostic biomarkers for non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP).

Abstract: A multilayer ceramic electronic component includes: a ceramic body including a dielectric layer and a first internal electrode and a second internal electrode a first external electrode and a second external electrode, wherein the ceramic body includes a capacitance formation portion including a first internal electrode and a second internal electrode stacked in a second direction to form capacitance, a first margin portion, a second margin portion, a first cover portion and a second cover portion, wherein an average length of the ceramic body in a first direction satisfies a range of exceeding 1 time and/or less than 3 times an average width (a) of the ceramic body in the second direction, wherein the average width (a) of the ceramic body in the second direction and an average height (b) of the ceramic body in a third direction satisfies a relationship of b>a.

Abstract: The present inventive concept provides a method of forming a dielectric film comprising a step of supplying a first source gas; a step of supplying a first purge gas; a step of supplying a first reaction gas; and a step of supplying a second purge gas, wherein the step of supplying the first source gas comprises supplying a compound containing at least one metal selected from the group consisting of lanthanum (La), cerium (Ce), strontium (Sr), gadolinium (Gd), hafnium (Hf), and zirconium (Zr) into a vacuum deposition apparatus, and wherein the step of supplying the first reaction gas comprises supplying a compound selected from the group consisting of O3 and H2O into the vacuum deposition apparatus.

Abstract: Therapeutic compounds for red blood cell-mediated delivery of an active pharmaceutical ingredient to a cancer cell are described. The therapeutic compounds are configured to bind CD47 on the surface of a red blood cell and to be subsequently transferred to CD47 on the surface of the cancer cell, the therapeutic compound ultimately being internalized by the target cell via endocytosis.

Abstract: Provided are a process for preparing (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine or a salt thereof, which is an intermediate useful for the preparation of tofacitinib, an intermediate used in the process, i.e., isopropanol solvate of methyl ((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)carbamate dibenzoyl-L-tartrate, an intermediate, having excellent stability, useful for the preparation of tofacitinib, i.e., (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine acetate, and a process for preparing tofacitinib or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure proposes an apparatus for determining a first three-dimensional shape of an object. The apparatus includes one or more first light sources configured to irradiate one or more first pattern lights to the object, a second light source configured to sequentially irradiate one or more second pattern lights having one phase range, a beam splitter and one or more lenses configured to change optical paths of the one or more second pattern lights, an image sensor configured to capture one or more first reflected lights and one or more second reflected lights, and a processor configured to determine the first three-dimensional shape of the object based on the one or more first reflected lights and the one or more second reflected lights.

Abstract: The present invention relates to a transmembrane domain derived from human LRRC24 protein. More specifically, the present invention relates to a transmembrane domain derived from the human LRRC24 protein (LRRC24P transmembrane domain) or a cell-penetrating peptide, and an intracellular delivery system comprising same. The transmembrane domain derived from the human LRRC24 protein of the present invention can be used to deliver cargo materials such as compounds, biomolecules, and various polymer materials into cells. Since the LRRC24P transmembrane domain of the present invention exhibits higher cell penetration efficiency compared to conventional cell-penetrating peptides and is derived from human proteins, thus avoiding side effects and immune responses caused by peptides derived from foreign proteins, it can be usefully used as an effective intracellular delivery method for compounds, biomolecules, and various polymer materials applied to the human body.

Abstract: Provided is BRCA-specific siRNA for enhancing the sensitivity of cancer cells to PARP inhibitors. According to the present disclosure, the siRNA can induce cancer cell death together with the PARP inhibitors in patients with wild-type BRCA genes with a low therapeutic effect of the PARP inhibitors, and the fusion protein-siRNA complex for siRNA delivery is up-taken into cells via CD47, and thus more specifically delivered to cancer cells while up-taken with high efficiency, thereby maximizing a desired cell death effect.

Abstract: The present disclosure proposes a detachable second apparatus coupled to a first apparatus that determines a first three-dimensional shape of an object and configured to determine an angle of an upper surface of the object. The second apparatus includes a first light source configured to sequentially irradiate first pattern lights having one phase range, a beam splitter and lenses configured to change optical paths of the first pattern lights so that a beam of light corresponding to a respective phase of the phase range spreads, and arrives at each point of a partial region of the upper surface of the object, a communication interface, and a first processor configured to obtain first information on first reflected lights generated by reflecting the first pattern lights from the partial region and determine the angle of the upper surface with respect to the reference plane based on the first information.

Abstract: A suspension arm includes a ball stud including a spherical ball; a bearing in which the spherical ball is accommodated; a housing having an inner peripheral portion and an outer peripheral portion; an arm body coupled to the outer peripheral portion of the housing; and an insert molding part which is injected to a lower portion of the bearing and the outer peripheral portion of the housing to be coupled to the bearing, the housing, and the arm body. The housing includes a matching portion having a matching surface formed to protrude in a radially outward direction from an upper portion of the outer peripheral portion and to be brought into contact with a mold. By forming the matching portion, it is possible to reduce the volume of the housing and to reduce the weight of the suspension arm while providing the matching surface with the mold.

Abstract: An inspection apparatus may include: a structured-light source configured to sequentially radiate a plurality of structured lights having one phase range; a lens configured to adjust, for each of the plurality of structured lights, optical paths of light beams corresponding to phases of the phase range such that a light beam corresponding to one phase of the phase range arrives at each point of a partial region on an object; an image sensor configured to capture a plurality of reflected lights generated by the structured lights being reflected from the partial region; and a processor configured to acquire a light quantity value of the reflected lights; and derive an angle of the surface by deriving phase values of the reflected lights based on the light quantity value for the reflected lights.

Abstract: A suspension arm device includes a body portion, and a panel portion including a plurality of fixing portions fixed to the body portion. One surfaces of the fixing portions which face the body portion have a shape in which the one surfaces correspond to an outer surface of the body portion.

Abstract: A brake apparatus for a vehicle according to an aspect of the present invention, the brake apparatus for a vehicle including a brake pad configured to pressurize a brake disc, a screw bar positioned inside a caliper body and rotated by receiving power from a motor part, a piston configured to pressurize the brake pad, and a nut rectilinearly moved due to a rotation of the screw bar, positioned inside the piston, and provided with a plurality of air discharge grooves, which are disposed to be spaced apart from each other to discharge air present inside the piston, and an air passage groove which connects the plurality of air discharge grooves.

Abstract: The present disclosure proposes a detachable second apparatus coupled to a first apparatus that determines a first three-dimensional shape of an object and configured to determine an angle of an upper surface of the object. The second apparatus includes a first light source configured to sequentially irradiate first pattern lights having one phase range, a beam splitter and lenses configured to change optical paths of the first pattern lights so that a beam of light corresponding to a respective phase of the phase range spreads, and arrives at each point of a partial region of the upper surface of the object, a communication interface, and a first processor configured to obtain first information on first reflected lights generated by reflecting the first pattern lights from the partial region and determine the angle of the upper surface with respect to the reference plane based on the first information.

Abstract: Therapeutic compounds for red blood cell-mediated delivery of an active pharmaceutical ingredient to a target cell are described. The therapeutic compounds are configured to bind CD47 on the surface of a red blood cell and to be subsequently transferred to CD47 on the surface of the target cell, the therapeutic compound ultimately being internalized by the target cell via endocytosis. The target cell may be a cancer cell.

Abstract: The present disclosure proposes an apparatus for determining a first three-dimensional shape of an object. The apparatus includes one or more first light sources configured to irradiate one or more first pattern lights to the object, a second light source configured to sequentially irradiate one or more second pattern lights having one phase range, a beam splitter and one or more lenses configured to change optical paths of the one or more second pattern lights, an image sensor configured to capture one or more first reflected lights and one or more second reflected lights, and a processor configured to determine the first three-dimensional shape of the object based on the one or more first reflected lights and the one or more second reflected lights.

Abstract: Therapeutic compounds for red blood cell-mediated delivery of an active pharmaceutical ingredient to a cancer cell are described. The therapeutic compounds are configured to bind CD47 on the surface of a red blood cell and to be subsequently transferred to CD47 on the surface of the cancer cell, the therapeutic compound ultimately being internalized by the cancer cell via endocytosis.

Abstract: Therapeutic compounds for inhibiting and reducing the expression of cell surface proteins and methods for treating cancer, inflammation, and diabetes using the therapeutic compounds.