Abstract: The present invention relates to a bitter-taste inhibitor containing indigestible maltodextrin, and to a ginseng composition comprising the bitter-taste inhibitor. According to the present invention, the particular bitter taste of ginseng may be eliminated without the loss of a marker component found in ginseng, thereby enabling the easy intake of ginseng.

Abstract: The present invention relates to an activin receptor type II B (ACVR2B) inhibitor which comprises the delta-like 1 homolog (DLK1) extracellular water-soluble domain. More specifically, the present invention relates to an extracellular soluble domain of DLK1; fragments of the extracellular soluble domain of DLK1; mutants of the extracellular soluble domain of DLK1; a composition for suppressing ligand linkage with the ACVR2B receptor, which includes a fragment of the mutants as an active ingredient; and a pharmaceutical composition for prevention and treatment of diseases which comprises the same. The composition of the present invention competitively binds to the ACVR2B receptor and inhibits the binding of an ACVR2B ligand to the ACVR2B receptor, which inhibits protein signalling associated with such ligands, and will be useful for prevention and treatment of diseases associated therewith.

Abstract: One controller for a power supply includes an oscillator, a first circuit, a counter, and a pause circuit. The first circuit generates a drive signal to control switching of a switch to regulate an output of the power supply. The first circuit initiates an on time period of the switch in response to both a clock signal of the oscillator and an enable signal that is generated in response to a feedback signal of the power supply. The counter receives the enable signal and generates an output signal when the counter reaches a count value indicating that the enable signal has been idle for an amount of time. The pause circuit generates a pause signal in response to the output signal of the counter. The oscillator is paused in response to the pause signal and a maximum on time period of the switch is extended while the oscillator is paused.

Abstract: A composition according to the present invention is a composition containing extract of Panax ginseng C.A. Meyer fruit as an active ingredient for preventing or treating artherosclerosis. The extract is confirmed to effectively suppress lesions or generation of a vascular inflammation factor caused by artherosclerosis. Thus, the composition is suitable for use as an active ingredient of the composition for preventing or treating artherosclerosis.

Abstract: The present invention relates to a transmitter and power supply which suffers little EMI deviation and provides adequate margin even in volume production, and which can cut the unit price of transformers and economize on the costs of EMI filters, by cancelling out and eliminating the conducted noise or the conducted noise and radiated noise caused by capacitive coupling between the windings of a transformer, the transformer being of an uncomplicated construction which is good in terms of production.

Abstract: One controller for a power supply includes an oscillator, a first circuit, a counter, and a pause circuit. The first circuit generates a drive signal to control switching of a switch to regulate an output of the power supply. The first circuit initiates an on time period of the switch in response to both a clock signal of the oscillator and an enable signal that is generated in response to a feedback signal of the power supply. The counter receives the enable signal and generates an output signal when the counter reaches a count value indicating that the enable signal has been idle for an amount of time. The pause circuit generates a pause signal in response to the output signal of the counter. The oscillator is paused in response to the pause signal and a maximum on time period of the switch is extended while the oscillator is paused.

Abstract: A recombinant expression vector, comprising extracellular soluble domain genes of DLK1 and IgG antibody Fc domain genes, is constructed, and DLK1-Fc fusion protein is expressed and purified at 293E cell. The invention confirmed the efficacy as a drug for inhibiting cancer metastasis by confirming markedly reduced migration of cancer cells by DLK1-Fc fusion protein and also computing pharmacokinetic parameters. DLK1-Fc fusion protein has relatively higher stability than non-fusion protein, significantly reduces migration of various cancer cell lines, and provides superior cancer metastasis inhibition effect even at small concentration. Accordingly, DLK1-Fc fusion protein can be used efficaciously as an effective ingredient of a composition for inhibiting cancer metastasis.

Abstract: A power converter control method and apparatus is disclosed. An example control circuit includes a clock signal generator coupled to generate a clock signal to control switching of a power switch to be coupled to the control circuit. A feedback circuit is coupled to receive a feedback signal which is representative of an output of a power converter during a duration of a feedback portion of an off time of the power switch. The feedback circuit is coupled to respond to the feedback signal to control the clock signal generator to regulate a ratio of the duration of the feedback portion of the off time of the power switch divided by a duration of a total power switch switching cycle period.

Abstract: One example controller for a power supply includes an oscillator, a drive signal generator, and a restart circuit. The oscillator generates a clock signal and the drive signal generator controls switching of a switch to regulate an output of the power supply in response to the clock signal. The restart circuit generates a restart signal in response to a current through the switch and in response to an absolute maximum on time period. The oscillator generates the clock signal to have a fixed maximum frequency in response to the restart signal indicating that the current through the switch reaches a current limit threshold within the absolute maximum on time period. The oscillator also generates the clock signal to have a variable minimum frequency in response to the restart signal indicating that the current through the switch has not reached the current limit threshold within the maximum on time period.

Abstract: Disclosed herein are exendin singly modified with polyethylene glycole or a derivative thereof, a method for the preparation of the same, and uses thereof. Exendin modified at lysine (27) with polyethylene glycol shows biological activity similar to that of natural exendin, but is improved in half life. In addition, the modification position and the number of PEG or its derivative are restricted so as to minimize the side effects caused by a variety of combinations of such factors. The exendin is useful in the prevention and treatment of diseases caused by the over-secretion of insulin, or diseases caused due to a decrease in plasma glucose level, the inhibition of gastric or intestinal motility, the promotion of satiety, or the inhibition of food intake, especially diabetes, obesity and irritable colon syndrome.

Abstract: The present disclosure discloses a method for treating vascular inflammation, improving skin beauty and improving male sexual function of a subject by administering a ginseng berry extract to the subject.

Abstract: A discontinuous mode flyback converter for limiting output current using primary feedback is disclosed. A transformer stores magnetic energy using field current and transfers the magnetic energy using a primary winding and a secondary winding closely coupled to the primary winding. A switching element is coupled to one end of the primary winding of the transformer and controls the current of the primary winding of the transformer. A control unit controls the switching element. A voltage error feedback unit feeds back the error of the output voltage of the transformer to the control unit, thereby regulating the output voltage. An output current feedback circuit detects the flyback period of the transformer, detects the output current information of the transformer from the rate of a flyback period in a cycle, and feeds it back to the control unit, thereby limiting the output current of the transformer.

Abstract: One example controller for a power supply includes an oscillator, a drive signal generator, and a restart circuit. The oscillator generates a clock signal and the drive signal generator controls switching of a switch to regulate an output of the power supply in response to the clock signal. The restart circuit generates a restart signal in response to a current through the switch and in response to an absolute maximum on time period. The oscillator generates the clock signal to have a fixed maximum frequency in response to the restart signal indicating that the current through the switch reaches a current limit threshold within the absolute maximum on time period. The oscillator also generates the clock signal to have a variable minimum frequency in response to the restart signal indicating that the current through the switch has not reached the current limit threshold within the maximum on time period.

Abstract: A power switch is switched to regulate an output of a power converter. A feedback signal representative of a power converter output during a feedback portion of an off time of the power switch is received. The feedback signal is above a threshold during a fraction of the feedback portion of the off time of the power switch and the feedback signal is below the threshold during another fraction of the feedback portion of the off time of the power switch. The fractions of the feedback portion of the off time of the power switch are regulated in response to the feedback signal by controlling the switching the power switch.

Abstract: The present invention relates to a ginseng mixed composition with improved bioavailability of saponin. Further, the present invention relates to a method for improving saponin bioavailability of a subject comprising: administering to the subject an effective amount of at least one extract selected from a Schizandra chinensis extract and a Liriope platyphylla extract that improves saponin bioavailability in the subject.

Abstract: Techniques are disclosed to extend an on time period of switch to regulate a transfer of energy from an input of a power supply to an output of a power supply. One example integrated circuit includes an energy transfer element coupled between an input and an output of the power supply. A switch is coupled to the input of the energy transfer element. A controller is coupled to the switch to control switching of the switch to regulate a transfer of energy from the input of the power supply to the output of the power supply in response to a feedback signal received from the output of the power supply. The controller is coupled to limit a maximum on time period of the switch a first maximum on time period in response to a first range of power supply operating conditions and to a second maximum on time period for a second range of power supply operating conditions.

Abstract: A power converter is disclosed. An example power converter includes an energy transfer element coupled between a power converter input and a power converter output. A power switch is coupled to the energy transfer element. A control circuit is coupled to receive a feedback signal representative of the power converter output during a feedback portion of an off time of the power switch. The control circuit is coupled to generate an output signal in response to the feedback signal. The output signal is coupled to be received by the power switch to control switching of the power switch to control a fraction of the feedback portion of the off time of the power switch that the feedback signal is above a threshold and another fraction of the feedback portion of the off time of the power switch that the feedback signal is below the threshold.

Abstract: A composition according to the present invention is a composition containing extract of Panax ginseng C.A. Meyer fruit as an active ingredient for preventing or treating artherosclerosis. The extract is confirmed to effectively suppress lesions or generation of a vascular inflammation factor caused by artherosclerosis. Thus, the composition is suitable for use as an active ingredient of the composition for preventing or treating artherosclerosis.

Abstract: A power converter control method and apparatus is disclosed. An example control circuit includes a clock signal generator coupled to generate a clock signal to control switching of a power switch to be coupled to the control circuit. A feedback circuit is coupled to receive a feedback signal which is representative of an output of a power converter during a duration of a feedback portion of an off time of the power switch. The feedback circuit is coupled to respond to the feedback signal to control the clock signal generator to regulate a ratio of the duration of the feedback portion of the off time of the power switch divided by a duration of a total power switch switching cycle period.

Abstract: An example power converter includes a clock signal generator coupled to generate a clock signal to control switching of a power switch to be coupled to the control circuit. Feedback circuitry is coupled to receive a feedback signal, which is representative of an output of a power converter during a feedback portion of an off time of the power switch. The feedback circuitry is coupled to respond to the feedback signal to control the clock signal generator to regulate a duty cycle of the feedback portion of the off time of the power switch as a proportion of a total power switch switching cycle period.