Patents by Inventor Chandan Ramaswamy Atreya

Chandan Ramaswamy Atreya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In-vitro magnetic resonance detection of a target substance without separating bound magnetic nanoparticles from unbound magnetic nanoparticles
    Patent number: 10156567
    Abstract: The present invention provides an in-vitro method for detecting the presence of a target substance in a biological sample by magnetic resonance, the method comprising: a) providing a mixture comprising a biological sample and a plurality of magnetic nanoparticles, wherein the magnetic nanoparticles comprise a binding agent capable of binding the target substance when the target substance is present in the biological sample; and b) determining a T2 relaxation time corresponding to magnetic nanoparticles that are bound to the target substance (T2bound) in the sample; wherein T2bound differs from the T2 relaxation time corresponding to the magnetic nanoparticles that are not bound to the target substance (T2free), and wherein T2bound is determined without physically separating magnetic nanoparticles that are bound to the target substance from the magnetic nanoparticles that are not bound to the target substance.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: December 18, 2018
    Assignee: General Electric Company
    Inventors: Ramesh Venkatesan, Arun Balasubramanian, Chandan Ramaswamy Atreya, Ravi Hedge, Ritika Uppal Mukherjee
  • IN-VITRO MAGNETIC RESONANCE DETECTION OF A TARGET SUBSTANCE
    Publication number: 20160195526
    Abstract: The present invention provides an in-vitro method for detecting the presence of a target substance in a biological sample by magnetic resonance, the method comprising: a) providing a mixture comprising a biological sample and a plurality of magnetic nanoparticles, wherein the magnetic nanoparticles comprise a binding agent capable of binding the target substance when the target substance is present in the biological sample; and b) determining a T2 relaxation time corresponding to magnetic nanoparticles that are bound to the target substance (T2bound) in the sample; wherein T2bound differs from the T2 relaxation time corresponding to the magnetic nanoparticles that are not bound to the target substance (T2free), and wherein T2bound is determined without physically separating magnetic nanoparticles that are bound to the target substance from the magnetic nanoparticles that are not bound to the target substance.
    Type: Application
    Filed: December 13, 2013
    Publication date: July 7, 2016
    Inventors: Ramesh VENKATESAN, Arun BALASUBRAMANIAN, Chandan Ramaswamy ATREYA, Ravi HEDGE, Ritika Uppal MUKHERJEE
  • NITROIMIDAZOLE DERIVATIVES
    Publication number: 20130078185
    Abstract: The present invention provides novel compounds useful in the treatment and diagnosis of mycobacterial infections. Compounds of the present invention have enhanced biological properties as compared to the related known compounds. The present invention also provides a precursor compound useful in the synthesis of certain compounds of the invention, and a method to obtain these compounds using said precursor compound. Methods of treatment and diagnosis in which the compounds of the invention fmd use are also provided.
    Type: Application
    Filed: May 31, 2011
    Publication date: March 28, 2013
    Applicant: GE HEALTHCARE LIMITED
    Inventors: Vijaya Raj Kuniyil Kulangara, Chandan Ramaswamy Atreya