Patents by Inventor Chandan Singh

Chandan Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel spiro-1,2,4-trioxanes
    Publication number: 20070191475
    Abstract: The present invention relates to spiro 1,2,4-trioxanes of general formula 4. This invention more particularly relates to a process for the preparation of a series of spiro 1,2,4-trioxanes. Wherein, Ar represents aryl groups such as phenyl, 4-biphenyl, 4-chlorophenyl, 4-methoxyphenyl, 4-methylphenyl, 4-cyclohexylphenyl, 1-naphthyl, 2-naphthyl and the like and R represents hydrogen or the alkyl group such as methyl, ethyl and the like. Several of these compounds show high order of antimalarial activity against multidrug-resistant malaria in mice and thus hold promise as antimalarial agents against multidrug-resistant malaria.
    Type: Application
    Filed: September 1, 2006
    Publication date: August 16, 2007
    Inventors: Chandan Singh, Heetika Malik, Sunil Puri
  • Substituted 1,2,4-trioxanes useful as antimalarial agents and a process for the preparation thereof
    Patent number: 6737438
    Abstract: In the present invention relates to a novel series of antimalarial 1,2,4-trioxanes analogues of general formula 7, wherein R represents cycloalkyl groups selected from the groups consisting of cyclopentyl, cyclohexyl, cycloheptyl and cyclooctyl or aryl groups selected from phenyl, 4-bromophenyl and 4-chlorophenyl, R1 and R2 represent hydrogen, alkyl group selected from methyl, ethyl, propyl and decyl, aryl selected from phenyl or parts of a cyclic systems such as cyclopentane, cyclohexane, substituted cyclohexane, cycloheptane bicyclo(2.2.1)heptane, adamantane and its preparation thereof; several of these novel compounds show promising antimalarial activity against multidrug resistant malaria in mice.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: May 18, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Chandan Singh, Pallvi Tiwari, Sunil Kumar Puri
  • Substituted 1,2,4-trioxanes useful as antimalarial agents and a process for the preparation thereof
    Publication number: 20040053991
    Abstract: In the present invention relates to a novel series of antimalarial 1,2,4-trioxanes analogues of general formula 7, 1
    Type: Application
    Filed: March 28, 2002
    Publication date: March 18, 2004
    Inventors: Chandan Singh, Pallvi Tiwari, Sunil Kumar Puri
  • Substituted 1,2,4-trioxanes as antimalarial agents and a process of producing the substituted 1,2,4-trioxanes
    Patent number: 6316493
    Abstract: The present invention relates to novel substituted 1,2,4-trioxanes that are useful as anti-malarial agents, and have a general formula 1, wherein R1 and R2 are selected from the group consisting of a hydrogen, a C1-11 alkyl group; R3 and R4 are selected from the group consisting of a hydrogen, a C1-11 alkyl group, a C3-10 aryl group, a C1-2CO2H carboxyalkyl group; and X represents hydrogen or a lower alkoxy group having 1 to 6 carbons.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: November 13, 2001
    Assignee: Council of Scientific and Industrial Research
    Inventors: Chandan Singh, Sunil Kumar Puri