Patents by Inventor Chandana Kolluru
Chandana Kolluru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170306178Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: ApplicationFiled: July 11, 2017Publication date: October 26, 2017Inventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Patent number: 9738813Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: GrantFiled: October 20, 2016Date of Patent: August 22, 2017Assignee: Novartis AGInventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Publication number: 20170037276Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: ApplicationFiled: October 20, 2016Publication date: February 9, 2017Inventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Publication number: 20170038501Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves autoclaving, in a sealed lens package, a silicone hydrogel contact lens having a base coating of polyacrylic acid thereon in an aqueous solution in the presence of a water-soluble, crosslinkable hydrophilic polymeric material having epoxide groups, for a period of time sufficient to covalently attach the crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one epoxide group and one of the carboxyl groups on and/or near the surface of the silicone hydrogel contact lens.Type: ApplicationFiled: October 25, 2016Publication date: February 9, 2017Inventors: Chandana Kolluru, Bradley Quinter
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Patent number: 9505184Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves autoclaving, in a sealed lens package, a silicone hydrogel contact lens having a base coating of polyacrylic acid thereon in an aqueous solution in the presence of a water-soluble, crosslinkable hydrophilic polymeric material having epoxide groups, for a period of time sufficient to covalently attach the crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one epoxide group and one of the carboxyl groups on and/or near the surface of the silicone hydrogel contact lens.Type: GrantFiled: November 13, 2012Date of Patent: November 29, 2016Assignee: Novartis AGInventors: Chandana Kolluru, Bradley Quinter
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Patent number: 9507173Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: GrantFiled: December 8, 2015Date of Patent: November 29, 2016Assignee: Novartis AGInventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Publication number: 20160091734Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: ApplicationFiled: December 8, 2015Publication date: March 31, 2016Inventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Patent number: 9239409Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: GrantFiled: December 16, 2014Date of Patent: January 19, 2016Assignee: Novartis AGInventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Patent number: 9156213Abstract: The invention provides a method of coating and thereby affecting the surface properties of a substrate such as a contact lens or other ophthalmic device. The method comprises the steps of generating an atmospheric plasma flow from a working gas and controlling the continuity of the atmospheric plasma flow with a power generator, and, introducing the atmospheric plasma flow to a substrate surface.Type: GrantFiled: November 23, 2011Date of Patent: October 13, 2015Assignee: Novartis AGInventors: Yongxing Qiu, John Dallas Pruitt, Chandana Kolluru, Maria A. Dunkle, Yasuo Matsuzawa
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Publication number: 20150099822Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: ApplicationFiled: December 16, 2014Publication date: April 9, 2015Inventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Patent number: 8944592Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: GrantFiled: July 23, 2013Date of Patent: February 3, 2015Assignee: Novartis AGInventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Publication number: 20130308093Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: ApplicationFiled: July 23, 2013Publication date: November 21, 2013Applicant: Novartis AGInventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo Norberto Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Patent number: 8529057Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: GrantFiled: July 29, 2011Date of Patent: September 10, 2013Assignee: Novartis AGInventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo N. Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson
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Publication number: 20120137635Abstract: The invention provides a method of coating and thereby affecting the surface properties of a substrate such as a contact lens or other ophthalmic device. The method comprises the steps of generating an atmospheric plasma flow from a working gas and controlling the continuity of the atmospheric plasma flow with a power generator, and, introducing the atmospheric plasma flow to a substrate surface.Type: ApplicationFiled: November 23, 2011Publication date: June 7, 2012Inventors: Yongxing Qiu, John Dallas Pruitt, Chandana Kolluru, Maria A. Dunkle, Yasuo Matsuzawa
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Publication number: 20120026457Abstract: The invention is related to a cost-effective method for making a silicone hydrogel contact lens having a crosslinked hydrophilic coating thereon. A method of the invention involves heating a silicone hydrogel contact lens in an aqueous solution in the presence of a water-soluble, highly branched, thermally-crosslinkable hydrophilic polymeric material having positively-charged azetidinium groups, to and at a temperature from about 40° C. to about 140° C. for a period of time sufficient to covalently attach the thermally-crosslinkable hydrophilic polymeric material onto the surface of the silicone hydrogel contact lens through covalent linkages each formed between one azetidinium group and one of the reactive functional groups on and/or near the surface of the silicone hydrogel contact lens, thereby forming a crosslinked hydrophilic coating on the silicone hydrogel contact lens. Such method can be advantageously implemented directly in a sealed lens package during autoclave.Type: ApplicationFiled: July 29, 2011Publication date: February 2, 2012Inventors: Yongxing Qiu, Newton T. Samuel, John Dallas Pruitt, Chandana Kolluru, Arturo N. Medina, Lynn Cook Winterton, Daqing Wu, Xinming Qian, Jared Nelson