Patents by Inventor Chandani Limbad

Chandani Limbad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 25-HYDROXYCHOLESTEROL (25HC), CRYAB AGGREGATION INHIBITOR, IS A NOVEL SENOLYTIC
    Publication number: 20220241316
    Abstract: Methods and compositions are provided herein that pertain to the discovery that the crystallin alpha B (CRYAB) gene and gene product provides an effective target for senolytic agents. In certain embodiments, methods of selectively killing one or more senescent cells in a subject in need thereof are provided wherein the method involves administering to the subject an effective amount of an agent that inhibits expression and/or aggregation of a CRYAB protein.
    Type: Application
    Filed: April 17, 2020
    Publication date: August 4, 2022
    Applicant: Buck Institute for Research on Aging
    Inventors: Chandani Limbad, Ryosuke Doi, Munemichi Ohe, Naoki Inoue