Abstract: The present invention describes a device and system for simulating normal and disease state cardiac functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a remote handheld electronic controller and manual adjustments from a main control panel, the air pressure level, fluidic pressure, and heart rate is controlled to induce contractions that simulate a wide variety of heart conditions ranging from normal heart function to severely diseased or injured heart conditions.