Patents by Inventor Chandra Has Khanduri

Chandra Has Khanduri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of ibrutinib
    Patent number: 11001585
    Abstract: The present invention relates to crystalline forms of ibrutinib, designated as Form S1, Form S2, Form S3, Form S4, and an amorphous form, designated as Form A1, and processes for their preparation, pharmaceutical compositions comprising these forms, and their use for the treatment of Bruton's tyrosine kinase (BTK) mediated diseases.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: May 11, 2021
    Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Ramkinkar Santra, Bala Krishna Reddy Bhogala, Chandra Has Khanduri
  • Ertugliflozin co-crystals and process for their preparation
    Patent number: 10294239
    Abstract: The present invention relates to processes for the preparation of an ertugliflozin-L-pyroglutamic acid (1:1) and co-crystal ertugliflozin-L-proline (1:1) co-crystal. The present invention further relates to an ertugliflozin-L-proline (1:2) co-crystal, processes for its preparation, and its use for the treatment of type 2 diabetes mellitus.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: May 21, 2019
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Ramkinkar Santra, Bala Krishna Reddy Bhogala, Chandra Has Khanduri
  • CRYSTALLINE FORMS OF IBRUTINIB
    Publication number: 20190002468
    Abstract: The present invention relates to crystalline forms of ibrutinib, designated as Form S1, Form S2, Form S3, Form S4, and an amorphous form, designated as Form A1, and processes for their preparation, pharmaceutical compositions comprising these forms, and their use for the treatment of Bruton's tyrosine kinase (BTK) mediated diseases.
    Type: Application
    Filed: August 10, 2016
    Publication date: January 3, 2019
    Inventors: Ramkinkar SANTRA, Bala Krishna Reddy BHOGALA, Chandra Has KHANDURI
  • ERTUGLIFLOZIN CO-CRYSTALS AND PROCESS FOR THEIR PREPARATION
    Publication number: 20180155358
    Abstract: The present invention relates to processes for the preparation of an ertugliflozin-L-pyroglutamic acid (1:1) and co-crystal ertugliflozin-L-proline (1:1) co-crystal. The present invention further relates to an ertugliflozin-L-proline (1:2) co-crystal, processes for its preparation, and its use for the treatment of type 2 diabetes mellitus.
    Type: Application
    Filed: May 24, 2016
    Publication date: June 7, 2018
    Inventors: Ramkinkar SANTRA, Bala Krishna Reddy BHOGALA, Chandra Has KHANDURI
  • Process for the preparation of tofacitinib and intermediates thereof
    Patent number: 9481679
    Abstract: The present invention provides compounds of Formula III and Formula VI, and processes for their preparation. The present invention further provides use of the compounds of Formula III and Formula VI for the preparation of tofacitinib or isomers or a mixture of isomers or salts thereof.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: November 1, 2016
    Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Mohammed Salman Hashmi, Yoginder Pal Sachdeva, Chandra Has Khanduri
  • PROCESS FOR THE PREPARATION OF TOFACITINIB AND INTERMEDIATES THEREOF
    Publication number: 20150322072
    Abstract: The present invention provides compounds of Formula III and Formula VI, and processes for their preparation. The present invention further provides use of the compounds of Formula III and Formula VI for the preparation of tofacitinib or isomers or a mixture of isomers or salts thereof.
    Type: Application
    Filed: December 17, 2013
    Publication date: November 12, 2015
    Inventors: Mohammed Salman HASHMI, Yoginder Pal SACHDEVA, Chandra Has KHANDURI
  • PROCESS FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF
    Publication number: 20150299160
    Abstract: The present invention provides processes for the preparation of rivaroxaban and its intermediates.
    Type: Application
    Filed: April 16, 2013
    Publication date: October 22, 2015
    Inventors: Pankaj Kumar SINGH, Mohammed Salman HASHMI, Yoginder Pal SACHDEVA, Chandra Has KHANDURI
  • PROCESS FOR THE PREPARATION OF OXCARBAZEPINE AND ITS USE AS INTERMEDIATE IN THE PREPARATION OF ESLICARBAZEPINE ACETATE
    Publication number: 20150232426
    Abstract: The present invention provides a process for the preparation of oxcarbazepine of Formula (1), which is an Active Pharmaceutical Ingredient (API) and a useful intermediate in the preparation of eslicarbazepine acetate of Formula (A). The present invention further provides a process for the preparation of eslicarbazepine acetate.
    Type: Application
    Filed: September 26, 2013
    Publication date: August 20, 2015
    Inventors: Ketan Hirpara, Kdv Jesunadh, Mukesh Kumar Sharma, Chandra Has Khanduri
  • PROCESS FOR THE PREPARATION OF RIVAROXABAN
    Publication number: 20150133657
    Abstract: The present invention provides processes for the preparation of rivaroxaban. The present invention also provides an intermediate for the preparation of rivaroxaban.
    Type: Application
    Filed: May 23, 2013
    Publication date: May 14, 2015
    Inventors: Pankaj Kumar Singh, Mukesh Kumar Sharma, Chandra Has Khanduri
  • PROCESS FOR THE PREPARATION AND PURIFICATION OF ESLICARBAZEPINE ACETATE AND INTERMEDIATES THEREOF
    Publication number: 20150065704
    Abstract: The present invention provides a novel process for the preparation of 10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide, commonly known as oxcarbazepine, which is a medicament and a useful intermediate in the preparation of eslicarbazepine acetate. The present invention further provides a process for the preparation and purification of eslicarbazepine acetate.
    Type: Application
    Filed: July 11, 2012
    Publication date: March 5, 2015
    Inventors: Ketan Hirpara, Chandra Has Khanduri, Mukesh Kumar Sharma
  • Process for the preparation of valganciclovir hydrochloride
    Patent number: 8586738
    Abstract: The present invention provides a novel process for the preparation of pure valganciclovir hydrochloride.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: November 19, 2013
    Inventors: Mohammed Salman Hashmi, Mukesh Kumar Sharma, Chandra Has Khanduri
  • Intermediate compounds and their use in preparation of lacosamide
    Patent number: 8378142
    Abstract: The present invention is concerned with novel compounds and their use for the preparation of lacosamide. The present invention also contemplates processes for the preparation of lacosamide employing the novel compound of general Formula II, Formula IIa or Formula IIb as intermediate. Wherein R1 is —OH or —OMe; R2 is —OH or —NH—CH2—C6H5.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: February 19, 2013
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Mukesh Kumar Madhra, Pankaj Kumar Singh, Chandra Has Khanduri
  • Process for the preparation of clopidogrel and its pharmaceutically acceptable salts
    Patent number: 8247558
    Abstract: The present invention provides a process for the preparation of clopidogrel and its pharmaceutically acceptable salts thereof comprises the resolving racemic methyl alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl)(2-chlorophenyl)-acetate by the salt formation of methyl alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl)(2-chlorophenyl)-acetate with excess levorotatory camphor-10-sulfonic acid to get a maximum yield of camphor sulphonate salt of methyl S-(+)-alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl) (2-chlorophenyl)-acetate and transforming the camphor sulphonate salt to clopidogrel or its pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: August 21, 2012
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Parendn Dhirajlal Rathod, Satish Kumar Aryan, Ram Chander Aryan, Chandra Has Khanduri
  • PROCESS FOR THE PREPARATION OF VALGANCICLOVIR HYDROCHLORIDE
    Publication number: 20120190850
    Abstract: The present invention provides a novel process for the preparation of pure valganciclovir hydrochloride.
    Type: Application
    Filed: August 12, 2010
    Publication date: July 26, 2012
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Mohammed Salman Hashmi, Mukesh Kumar Sharma, Chandra Has Khanduri
  • PROCESS FOR THE PREPARATION OF QUETIAPINE FUMARATE
    Publication number: 20120071649
    Abstract: The present invention relates to an improved process for the preparation of quetiapine and pharmaceutically acceptable salts. It also relates to improved process for the preparation of intermediates of quetiapine.
    Type: Application
    Filed: March 4, 2010
    Publication date: March 22, 2012
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Venugopal Venkatarama Durvasula, Parendu Dhirajlal Rathod, Ram Chandra Aryan, Chandra Has Khanduri
  • Intermediate compounds and their use in preparation of lacosamide
    Patent number: 8093426
    Abstract: The present invention is concerned with novel compounds and their use for the preparation of lacosamide. The present invention also contemplates processes for the preparation of lacosamide employing the novel compound of general Formula II, Formula IIa or Formula IIb as intermediate. Wherein R1 is —OH or —OMe; R2 is —OH or —NH—CH2—C6H5.
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: January 10, 2012
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Mukesh Kumar Madhra, Pankaj Kumar Singh, Chandra Has Khanduri
  • INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE
    Publication number: 20120004462
    Abstract: The present invention is concerned with novel compounds and their use for the preparation of lacosamide. The present invention also contemplates processes for the preparation of lacosamide employing the novel compound of general Formula II, Formula IIa or Formula IIb as intermediate. Wherein R1 is —OH or —OMe; R2 is —OH or —NH—CH2—C6H5.
    Type: Application
    Filed: June 7, 2011
    Publication date: January 5, 2012
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Mukesh Kumar MADHRA, Pankaj Kumar Singh, Chandra Has Khanduri
  • INTERMEDIATE COMPOUNDS AND THEIR USE IN PREPARATION OF LACOSAMIDE
    Publication number: 20120004452
    Abstract: The present invention is concerned with novel compounds and their use for the preparation of lacosamide. The present invention also contemplates processes for the preparation of lacosamide employing the novel compound of general Formula II, Formula IIa or Formula IIb as intermediate. Wherein R1 is —OH or —OMe; R2 is —OH or —NH—CH2—C6H5.
    Type: Application
    Filed: June 7, 2011
    Publication date: January 5, 2012
    Inventors: Mukesh Kumar MADHRA, Pankaj Kumar Singh, Chandra Has Khanduri
  • PROCESS FOR THE PREPARATION OF CLOPIDOGREL HYDROGEN SULPHATE FORM I
    Publication number: 20110263858
    Abstract: The present invention relates to a process for the preparation of Form 1 of (+)-(S)-?-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid methyl ester hydrogen sulphate commonly known as clopidogrel bisulphate. The present invention further relates to a process for reducing the residual amount of methyl isobutyl ketone and controlling the amount of mesityl oxide in clopidogrel hydrogen sulphate Form 1 by washing with ethyl acetate. Formula (I).
    Type: Application
    Filed: October 20, 2009
    Publication date: October 27, 2011
    Inventors: Satish Kumar Aryan, Parendu Dhirajlal Rathod, Ram Chander Aryan, Chandra Has Khanduri
  • PROCESS FOR PREPARATION OF AMORPHOUS LOPINAVIR
    Publication number: 20110224435
    Abstract: The present invention relates to a process for preparation of amorphous lopinavir, which is HIV protease inhibitor of Formula (I). Using agitated film drying.
    Type: Application
    Filed: August 6, 2008
    Publication date: September 15, 2011
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Sujoy Biswas, Ramendra Singh Rathore, Keya Karanjai, Chandra Has Khanduri