Abstract: Sulfone-containing polythioethers, compositions containing sulfone-containing polythioethers, methods of synthesizing sulfone-containing polythioethers and the use of sulfone-containing polythioethers in aerospace sealant applications are disclosed. The sulfone-containing polythioethers have sulfone groups incorporated into the backbone of the polythioether. Cured sealant compositions comprising the sulfone-containing polythioethers exhibit enhanced thermal resistance.

Abstract: Provided herein are isolated CD3×PSMA-bispecific antigen-binding molecules or bispecific antigen-binding fragment thereof wherein a FN3 domain specifically binds human prostate specific membrane antigen (PSMA) and a second antigen-binding site immunospecifically binds CD3. Also described are fusion proteins and related polynucleotides capable of encoding the provided fusion proteins and, cells expressing the provided fusion proteins. In addition, methods of using the provided isolated CD3×PSMA-bispecific antigen-binding molecules or bispecific antigen-binding fragment thereof are described.

Abstract: Disclosed are methods for making a cured sealant. The methods include depositing an uncured sealant composition on a substrate and exposing the uncured sealant composition to actinic radiation to provide a cured sealant. The uncured sealant composition includes a thiol-terminated polythioether, a polyene comprising a polyvinyl ether and/or a polyallyl compound, and a hydroxy-functional vinyl ether. Related sealant compositions are also disclosed.

Abstract: Low-density compositions and sealants prepared from sulfur-containing prepolymer compositions that exhibit enhanced fuel resistance are disclosed. The low density and enhanced fuel resistance is realized by using polyphenylene sulfide fillers.

Abstract: Disclosed are flexible polyamines, flexible amine-terminated polyformal adducts, flexible-amine-terminated polythioether adducts, compositions comprising flexible polyamines and isocyanate-terminated prepolymers, and compositions comprising flexible amine-terminated adducts and isocyanate-terminated prepolymers. Uses of the compositions as sealants, and particularly as aerospace sealants, are also disclosed.

Abstract: Low-density compositions and sealants prepared from sulfur-containing prepolymer compositions that exhibit enhanced fuel resistance are disclosed. The low density and enhanced fuel resistance is realized by using polyphenylene sulfide fillers.

Abstract: Methods for fabricating dual damascene structures are provided herein. In some embodiments, a method for fabricating a dual damascene interconnect structure may include patterning a first mask layer atop a substrate disposed in a process chamber, wherein the substrate includes one or more low temperature dielectric layers to define a first etch pattern, and wherein the one or more low temperature dielectric layers are formed atop the substrate at a temperature below about 180 degrees Celsius; etching the first etch pattern into the one or more low temperature dielectric layers; patterning a second mask layer atop the substrate to define a second etch pattern, wherein the first etch pattern and the second etch pattern are aligned; and etching the second etch pattern into the one or more low temperature dielectric layers to form a dual damascene pattern in the substrate.

Abstract: Metal ligand-containing prepolymers, compositions containing metal ligand-containing prepolymers, methods of synthesizing metal ligand-containing prepolymers and the use of metal ligand-containing prepolymers in aerospace sealant applications are disclosed. The metal ligand-containing prepolymers have metal ligands incorporated into the backbone of the prepolymer. Cured sealant compositions comprising the metal ligand-containing prepolymers exhibit enhanced properties suitable for aerospace sealant applications.

Abstract: Disclosed are adhesion promoting adducts containing adhesion promoting groups and metal ligands and compositions such as sealant compositions useful in aerospace applications comprising the adhesion promoting adducts. The adhesion promoting adducts are useful as adhesion promoting additives or as a copolymerizable reactant in polymer compositions.

Abstract: Provided are methods for detecting or isolating circulating tumor cells (CTCs) in a subject. The methods may include detecting the expression of at least one epithelial mesenchymal transition (EMT) biomarker. Further provided are kits for detecting or isolating CTCs. The kits may include antibodies to at least one EMT biomarker. Further provided are methods of predicting the responsiveness of a subject to a cancer drug, methods of targeting delivery of a cancer drug in a subject, methods of providing a cancer prognosis to a subject, and methods for following the progress of cancer in a subject.

Abstract: A nozzle for uniform plasma processing comprises an inlet portion and an outlet portion. The inlet portion has a side surface substantially parallel to a vertical axis. The inlet portion comprises a plurality of gas channels. The outlet portion is coupled to the inlet portion. The outlet portion comprises a plurality of outlets. At least one of the outlets is at an angle other than a right angle relative to the vertical axis.

Abstract: This presentation provides methods to track pedestrians heading angle using smart phone data. Tracking heading angle especially at or from stationary position is key for pedestrian safety, e.g., for smart cross system and pedestrian collision mitigation system. It provides pedestrian-to-vehicle (P2V) platform. It deploys smart phones or mobile devices, equipped with DSRC (Dedicated short range communication) support, to act as beacons for pedestrians: Phone can alert driver to pedestrian presence in path; Pedestrian Basic Safety Message (BSM) can aid awareness for vehicles; It can be used for bicycles, as well. It also provides pedestrian-to-infrastructure (P2I) platform. Smart phone, through DSRC/cellular, transmits pedestrian presence to crosswalks/signals: It enables advanced crosswalk lighting/warning scheme; It enables bundling of pedestrian presence to vehicles. In this presentation, we provide various examples and variations on these.

Abstract: Disclosed are perfluoroethers and perfluoroether compositions useful in high temperature aerospace applications. The perfluoroethers can be adapted for use with various curing chemistries.

Abstract: Metal ligand-containing prepolymers, compositions containing metal ligand-containing prepolymers, methods of synthesizing metal ligand-containing prepolymers and the use of metal ligand-containing prepolymers in aerospace sealant applications are disclosed. The metal ligand-containing prepolymers have metal ligands incorporated into the backbone of the prepolymer. Cured sealant compositions comprising the metal ligand-containing prepolymers exhibit enhanced properties suitable for aerospace sealant applications.

Abstract: Sulfone-containing polythioethers, compositions containing sulfone-containing polythioethers, methods of synthesizing sulfone-containing polythioethers and the use of sulfone-containing polythioethers in aerospace sealant applications are disclosed. The sulfone-containing polythioethers have sulfone groups incorporated into the backbone of the polythioether. Cured sealant compositions comprising the sulfone-containing polythioethers exhibit enhanced thermal resistance.

Abstract: Disclosed are compositions that include: a) a thiol-terminated polymer; and b) a sulfur-containing ethylenically unsaturated silane. Related products, such as sealants, that include polymers derived from such compositions, are also disclosed.

Abstract: Sulfone-containing polythioethers, compositions containing sulfone-containing polythioethers, methods of synthesizing sulfone-containing polythioethers and the use of sulfone-containing polythioethers in aerospace sealant applications are disclosed. The sulfone-containing polythioethers have sulfone groups incorporated into the backbone of the polythioether. Cured sealant compositions comprising the sulfone-containing polythioethers exhibit enhanced thermal resistance.

Abstract: Metal ligand-containing prepolymers, compositions containing metal ligand-containing prepolymers, methods of synthesizing metal ligand-containing prepolymers and the use of metal ligand-containing prepolymers in aerospace sealant applications are disclosed. The metal ligand-containing prepolymers have metal ligands incorporated into the backbone of the prepolymer. Cured sealant compositions comprising the metal ligand-containing prepolymers exhibit enhanced properties suitable for aerospace sealant applications.

Abstract: Sulfur-containing polymer adducts such as polythioethers, polysulfides, and sulfur-containing polyformals having terminal maleimide groups, and in particular, sulfur-containing polymers and sulfur containing adducts having terminal 1,1?-(methylenedi-4,1-phenylene)bismaleimide groups are disclosed. The adducts provide cured sealants having improved tensile strength and elongation and are useful as aerospace sealants.

Abstract: Disclosed are perfluoroethers and perfluoroether compositions useful in high temperature aerospace applications. The perfluoroethers can be adapted for use with various curing chemistries.