Patents by Inventor Chandrakala Pidathala

Chandrakala Pidathala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating pain
    Patent number: 10449198
    Abstract: The present invention relates to a method of treating pain in a patient in need of such treatment, said method comprising administering to said patient a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt or solvate: wherein Q is as defined herein.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: October 22, 2019
    Assignee: The University of Liverpool
    Inventors: Martin Leuwer, Paul O'Neill, Neil Berry, Chandrakala Pidathala
  • Pharmacologically active compounds
    Patent number: 10442814
    Abstract: The present invention relates to compounds of formula I shown below: wherein Q is as defined herein. The compounds of formula I act as selective positive allosteric modulators of strychnine-sensitive alpha 1-glycine receptors. The present invention further relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of diseases or conditions in which strychnine-sensitive alpha 1-glycine receptor activity is implicated (such as, for example, chronic pain. The present invention also relates to processes for the preparation of these compounds and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: October 15, 2019
    Assignee: University of Liverpool
    Inventors: Martin Leuwer, Paul M. O'Neill, Neil Berry, Chandrakala Pidathala
  • PHARMACOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20190084993
    Abstract: The present invention relates to compounds of formula I shown below: wherein Q is as defined herein. The compounds of formula I act as selective positive allosteric modulators of strychnine-sensitive alpha 1-glycine receptors. The present invention further relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of diseases or conditions in which strychnine-sensitive alpha 1-glycine receptor activity is implicated (such as, for example, chronic pain. The present invention also relates to processes for the preparation of these compounds and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: April 13, 2018
    Publication date: March 21, 2019
    Applicant: The University of Liverpool
    Inventors: Martin Leuwer, Paul M. O'Neill, Neil Berry, Chandrakala Pidathala
  • METHOD
    Publication number: 20180140608
    Abstract: The present invention relates to a method of treating pain in a patient in need of such treatment, said method comprising administering to said patient a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt or solvate: wherein Q is as defined herein.
    Type: Application
    Filed: July 5, 2017
    Publication date: May 24, 2018
    Inventors: Martin Leuwer, Paul O'Neill, Neil Berry, Chandrakala Pidathala
  • Pharmacologically active compounds
    Patent number: 9944653
    Abstract: The present invention relates to compounds of formula I shown below: wherein Q is as defined herein. The compounds of formula I act as selective positive allosteric modulators of strychnine-sensitive alpha 1-glycine receptors. The present invention further relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of diseases or conditions in which strychnine-sensitive alpha 1-glycine receptor activity is implicated (such as, for example, chronic pain. The present invention also relates to processes for the preparation of these compounds and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: April 17, 2018
    Assignee: THE UNIVERSITY OF LIVERPOOL
    Inventors: Martin Leuwer, Paul O'Neill, Neil Berry, Chandrakala Pidathala
  • PHARMACOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20170298076
    Abstract: The present invention relates to compounds of formula I shown below: wherein Q is as defined herein. The compounds of formula I act as selective positive allosteric modulators of strychnine-sensitive alpha 1-glycine receptors. The present invention further relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of diseases or conditions in which strychnine-sensitive alpha 1-glycine receptor activity is implicated (such as, for example, chronic pain. The present invention also relates to processes for the preparation of these compounds and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: May 4, 2017
    Publication date: October 19, 2017
    Inventors: Martin Leuwer, Paul O'Neill, Neil Berry, Chandrakala Pidathala
  • Pharmacologically active compounds
    Patent number: 9676786
    Abstract: The present invention relates to compounds of formula I shown below: wherein Q is as defined herein. The compounds of formula I act as selective positive allosteric modulators of strychnine-sensitive alpha 1-glycine receptors. The present invention further relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of diseases or conditions in which strychnine-sensitive alpha 1-glycine receptor activity is implicated (such as, for example, chronic pain. The present invention also relates to processes for the preparation of these compounds and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: June 13, 2017
    Assignee: THE UNIVERSITY OF LIVERPOOL
    Inventors: Martin Leuwer, Paul O'Neill, Neil Berry, Chandrakala Pidathala
  • PHARMACOLOGICALLY ACTIVE COMPOUNDS
    Publication number: 20160318947
    Abstract: The present invention relates to compounds of formula I shown below: wherein Q is as defined herein. The compounds of formula I act as selective positive allosteric modulators of strychnine-sensitive alpha 1-glycine receptors. The present invention further relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of diseases or conditions in which strychnine-sensitive alpha 1-glycine receptor activity is implicated (such as, for example, chronic pain. The present invention also relates to processes for the preparation of these compounds and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: December 23, 2014
    Publication date: November 3, 2016
    Applicant: The University of Liverpool
    Inventors: Martin Leuwer, Paul O'Neill, Neil Berry, Chandrakala Pidathala