Abstract: This is a method and a system for designing a personalized therapeutic intervention for an individual. Each individual has a unique composition of microbiome in the gut, one probiotic or dietary regimen may not have same efficacy in different individuals. The disclosure recommends a personalized therapeutic intervention for improving gut health of an individual by designing personalized therapeutics and diet based on functions of microbiome. The personalized therapeutic intervention is recommended based on several steps including generating a set of knowledge bases, identifying a change in the gut health of an individual by monitoring the gut samples and recommending a personalized therapeutic intervention. The personalized therapeutic intervention comprises at least one of a prebiotic, a probiotic and an optimized diet, wherein the optimized diet is estimated based on optimizing a gut food score, where the gut food score is computed based on the change in the gut health of an individual.

Abstract: A system and method for predicting gut health of an individual using non-invasive technique has been provided. The system is making use of two types of pathways i.e. one which are beneficial to gut health and the second which are harmful to gut health. These two types of pathways are annotated in the genomes of gut bacteria. Best combinations of subsets of these pathways capable of distinguishing between gut commensals and pathogens are assigned as pathway biomarkers. The identified pathway biomarkers are then used to develop scheme for prediction of gut health status.

Abstract: A system and method for predicting gut health of an individual using non-invasive technique has been provided. The system is making use of two types of pathways i.e. one which are beneficial to gut health and the second which are harmful to gut health. These two types of pathways are annotated in the genomes of gut bacteria. Best combinations of subsets of these pathways capable of distinguishing between gut commensals and pathogens are assigned as pathway biomarkers. The identified pathway biomarkers are then used to develop scheme for prediction of gut health status.