Patents by Inventor Chandru Chandrasekaran
Chandru Chandrasekaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8647359Abstract: Methods and devices for capturing debris within a blood vessel are disclosed. A filter assembly in accordance with the present invention comprises an elongate shaft having a proximal end and a distal end, and a filter fixed to the elongate shaft proximate the distal end thereof. A filter assembly in accordance with the present invention may further include a means for reducing the volume of the debris that is disposed within the filter.Type: GrantFiled: January 10, 2002Date of Patent: February 11, 2014Assignee: Boston Scientific Scimed, Inc.Inventors: Thomas E. Broome, Verivada (Chandru) Chandrasekaran, John M. K. Daniel, James E. Mayberry
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Patent number: 8187620Abstract: The invention relates generally to a medical device, such as an intravascular stent, for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. More particularly, the invention pertains to a medical device having a metal oxide or metal material with a plurality of pores therein disposed on the surface of the medical device and a polymer disposed on the metal oxide or metal material. The invention also relates to medical devices having a surface and an outer region comprising a metal oxide or metal material having a plurality of pores therein and a polymer disposed on the metal oxide or metal material.Type: GrantFiled: March 27, 2006Date of Patent: May 29, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: Chandru Chandrasekaran, Rajesh Radhakrishnan
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Patent number: 8133278Abstract: According to one aspect, the present invention provides implantable or insertable medical devices that comprise a substrate and a coating over the substrate that comprises at least one type of conductive polymer and at least one type of additional polymer.Type: GrantFiled: August 12, 2009Date of Patent: March 13, 2012Assignee: Boston Scientific Scimed, Inc.Inventors: Liliana Atanasoska, Chandru Chandrasekaran, Robert W. Warner, Jan Weber
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Patent number: 7985252Abstract: An endoprosthesis includes a plurality of struts defining a flow passage. At least one strut includes (a) a body comprising a bioerodible material and having a thickness and (b) a coating overlying the body. The coating includes a plurality of regions that allow physiological fluids to contact a plurality of corresponding areas of the underlying body when the endoprosthesis is implanted in a physiological environment. The plurality of regions are sized and arranged so that the contacted areas of the body erode substantially through the body in the thickness direction while the coating remains on the body when the endoprosthesis is implanted in the physiological environment.Type: GrantFiled: July 30, 2008Date of Patent: July 26, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Rajesh Radhakrishnan, Chandru Chandrasekaran, Scott R. Schewe, Ken Merdan
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Publication number: 20110118826Abstract: An endoprosthesis includes a plurality of struts defining a flow passage. At least one strut includes (a) a body comprising a bioerodible material and having a thickness and (b) a coating overlying the body. The coating includes a plurality of regions that allow physiological fluids to contact a plurality of corresponding areas of the underlying body when the endoprosthesis is implanted in a physiological environment. The plurality of regions are sized and arranged so that the contacted areas of the body erode substantially through the body in the thickness direction while the coating remains on the body when the endoprosthesis is implanted in the physiological environment.Type: ApplicationFiled: January 26, 2011Publication date: May 19, 2011Applicant: Boston Scientific SciMed. Inc.Inventors: Rajesh Radhakrishnan, Chandru Chandrasekaran, Scott R. Schewe, Ken Merdan
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Publication number: 20110112617Abstract: A medical electrical lead and body implantable electrode suitable for a variety of medical applications are disclosed. In general, the electrode includes a composite material having particles of pseudo-capacitive material, such as iridium oxide, dispersed within a polymer matrix including a polyelectrolyte. The polymer matrix can also include a conductive polymer doped with an excess of the polyelectrolyte. The composite may used to form the electrode itself or an electrode coating. The presence of a pseudo-capacitive material within the composite may increase the charge-storage capacity of the electrode and may allow for safe deliveries of charge densities within an electrochemical window suitable for pacing a patient's heart.Type: ApplicationFiled: January 20, 2011Publication date: May 12, 2011Inventors: L. Liliana Atanasoska, J. Lee Shippy, III, Tracee E.J. Eidenschink, Chandru Chandrasekaran
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Patent number: 7935379Abstract: The present invention relates generally to coated medical devices, preferably a stent, that has a drug-eluting surface completely or partially coated with a coating that is imprinted with an impression. In particular, the invention is directed to a coated medical device having a coating that comprises biologically active materials, polymers, or a combination thereof. The coating is imprinted with an impression by printing, molding, lithography, or embossing techniques. Preferably, the patterning imprinted on the coating is capable of releasing biologically active materials in different amounts, at different rates, and/or at different time periods. The invention also relates to methods of making and methods of using the coated medical device.Type: GrantFiled: November 14, 2005Date of Patent: May 3, 2011Assignee: Boston Scientific Scimed, Inc.Inventors: Rajesh Radhakrishnan, Chandru Chandrasekaran
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Patent number: 7899552Abstract: A medical electrical lead and body implantable electrode suitable for a variety of medical applications are disclosed. In general, the electrode includes a composite material having particles of pseudo-capacitive material, such as iridium oxide, dispersed within a polymer matrix including a polyelectrolyte. The polymer matrix can also include a conductive polymer doped with an excess of the polyelectrolyte. The composite may used to form the electrode itself or an electrode coating. The presence of a pseudo-capacitive material within the composite may increase the charge-storage capacity of the electrode and may allow for safe deliveries of charge densities within an electrochemical window suitable for pacing a patient's heart.Type: GrantFiled: September 24, 2008Date of Patent: March 1, 2011Assignee: Cardiac Pacemakers, Inc.Inventors: L. Liliana Atanasoska, J. Lee Shippy, III, Tracee E. J. Eidenschink, Chandru Chandrasekaran
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Publication number: 20100042205Abstract: According to one aspect, the present invention provides implantable or insertable medical devices that comprise a substrate and a coating over the substrate that comprises at least one type of conductive polymer and at least one type of additional polymer.Type: ApplicationFiled: August 12, 2009Publication date: February 18, 2010Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Liliana Atanasoska, Chandru Chandrasekaran, Robert W. Warner, Jan Weber
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Publication number: 20100030326Abstract: An endoprosthesis includes a plurality of struts defining a flow passage. At least one strut includes (a) a body comprising a bioerodible material and having a thickness and (b) a coating overlying the body. The coating includes a plurality of regions that allow physiological fluids to contact a plurality of corresponding areas of the underlying body when the endoprosthesis is implanted in a physiological environment. The plurality of regions are sized and arranged so that the contacted areas of the body erode substantially through the body in the thickness direction while the coating remains on the body when the endoprosthesis is implanted in the physiological environment.Type: ApplicationFiled: July 30, 2008Publication date: February 4, 2010Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Rajesh Radhakrishnan, Chandru Chandrasekaran, Scott R. Schewe, Ken Merdan
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Publication number: 20090099634Abstract: A medical electrical lead and body implantable electrode suitable for a variety of medical applications are disclosed. In general, the electrode includes a composite material having particles of pseudo-capacitive material, such as iridium oxide, dispersed within a polymer matrix including a polyelectrolyte. The polymer matrix can also include a conductive polymer doped with an excess of the polyelectrolyte. The composite may used to form the electrode itself or an electrode coating. The presence of a pseudo-capacitive material within the composite may increase the charge-storage capacity of the electrode and may allow for safe deliveries of charge densities within an electrochemical window suitable for pacing a patient's heart.Type: ApplicationFiled: September 24, 2008Publication date: April 16, 2009Inventors: L. Liliana Atanasoska, J. Lee Shippy, III, Tracee E. J. Eidenschink, Chandru Chandrasekaran
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Publication number: 20070224116Abstract: The invention relates generally to a medical device, such as an intravascular stent, for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. More particularly, the invention pertains to a medical device having a metal oxide or metal material with a plurality of pores therein disposed on the surface of the medical device and a polymer disposed on the metal oxide or metal material. The invention also relates to medical devices having a surface and an outer region comprising a metal oxide or metal material having a plurality of pores therein and a polymer disposed on the metal oxide or metal material.Type: ApplicationFiled: March 27, 2006Publication date: September 27, 2007Inventors: Chandru Chandrasekaran, Rajesh Radhakrishnan
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Publication number: 20070184085Abstract: A medical device comprising a medical device body having drug-loaded vesicles thereon. The vesicles are ultrasound sensitive and release the drug upon ultrasound stimulation. Also provided is a method for controlling drug release from a medical device using drug-loaded vesicles that are ultrasound sensitive.Type: ApplicationFiled: February 3, 2006Publication date: August 9, 2007Inventors: Rajesh Radhakrishnan, Chandru Chandrasekaran
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Publication number: 20070110888Abstract: The present invention relates generally to coated medical devices, preferably a stent, that has a drug-eluting surface completely or partially coated with a coating that is imprinted with an impression. In particular, the invention is directed to a coated medical device having a coating that comprises biologically active materials, polymers, or a combination thereof. The coating is imprinted with an impression by printing, molding, lithography, or embossing techniques. Preferably, the patterning imprinted on the coating is capable of releasing biologically active materials in different amounts, at different rates, and/or at different time periods. The invention also relates to methods of making and methods of using the coated medical device.Type: ApplicationFiled: November 14, 2005Publication date: May 17, 2007Inventors: Rajesh Radhakrishnan, Chandru Chandrasekaran
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Publication number: 20070043433Abstract: The present invention provides an intraluminal stent comprising a metallic reinforcing component and a biodegradable polymeric material covering at least a portion of the metallic reinforcing component. The metallic reinforcing component provides structural reinforcement for the stent, but this reinforcement is insufficient, in the absence of the biodegradable polymeric material, to provide a stent capable of maintaining patency of a lumen upon implantation of the stent into the lumen. One advantage of the present invention, among others, is that a stent is provided in which reduced amounts of metallic component remain after degradation of the biodegradable polymeric material covering, in turn reducing the incidence of metal-associated adverse events that frequently follow implantation.Type: ApplicationFiled: October 31, 2006Publication date: February 22, 2007Inventor: Chandru Chandrasekaran
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Patent number: 7029440Abstract: Distal protection filter frame and method for using and manufacturing the same. A distal protection filter frame may include one or more struts, a mouth, and a filter coupled to the mouth.Type: GrantFiled: March 13, 2002Date of Patent: April 18, 2006Assignee: Scimed Life Systems, Inc.Inventors: Thomas E. Broome, James M. Anderson, Robert L. Cassell, Verivada (Chandru) Chandrasekaran, John M. K. Daniel, Bradley F. Slaker, Jeffrey H. Vogel
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Patent number: 6800083Abstract: A rotational ablation atherectomy device including a flexible drive shaft and a compressible burr that may be inserted and extracted from a patient using a catheter having a diameter that is smaller than the operational diameter of the burr. In one embodiment, the burr includes a nose portion coupled to the drive shaft and one or more flexible abrasive disks disposed rearwardly from the nose portion. The flexible disks are foldable to be slidably received within a catheter. In another embodiment, the burr includes a support member coupled to the drive shaft, the support member having a resilient panel that spirals outwardly, forming a generally cylindrical ablation surface. The flexible panel can be elastically urged toward the support member and slidably inserted into the catheter. In a third embodiment, the burr includes a plurality of struts that are coupled to the drive shaft. An elastically compressible body disposed between the struts permits the struts to flex inwardly to reduce the burr diameter.Type: GrantFiled: April 9, 2001Date of Patent: October 5, 2004Assignee: SciMed Life Systems, Inc.Inventors: Thomas J. Hiblar, Robert L. Barry, Edward Wulfman, Zihong Guo, Verivada Chandru Chandrasekaran
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Publication number: 20030176885Abstract: Distal protection filter frame and method for using and manufacturing the same. A distal protection filter frame may include one or more struts, a mouth, and a filter coupled to the mouth.Type: ApplicationFiled: March 13, 2002Publication date: September 18, 2003Applicant: SCIMED LIFE SYSTEMS, INC.Inventors: Thomas E. Broome, James M. Anderson, Robert L. Cassell, Verivada (Chandru) Chandrasekaran, John M.K. Daniel, Bradley F. Slaker, Jeffrey H. Vogel
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Publication number: 20030153971Abstract: The present invention provides an intraluminal stent comprising a metallic reinforcing component and a biodegradable polymeric material covering at least a portion of the metallic reinforcing component. The metallic reinforcing component provides structural reinforcement for the stent, but this reinforcement is insufficient, in the absence of the biodegradable polymeric material, to provide a stent capable of maintaining patency of a lumen upon implantation of the stent into the lumen. One advantage of the present invention, among others, is that a stent is provided in which reduced amounts of metallic component remain after degradation of the biodegradable polymeric material covering, in turn reducing the incidence of metal-associated adverse events that frequently follow implantation.Type: ApplicationFiled: February 14, 2002Publication date: August 14, 2003Inventor: Chandru Chandrasekaran
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Publication number: 20030130682Abstract: Methods and devices for capturing debris within a blood vessel are disclosed. A filter assembly in accordance with the present invention comprises an elongate shaft having a proximal end and a distal end, and a filter fixed to the elongate shaft proximate the distal end thereof. A filter assembly in accordance with the present invention may further include a means for reducing the volume of the debris that is disposed within the filter.Type: ApplicationFiled: January 10, 2002Publication date: July 10, 2003Applicant: SCIMED LIFE SYSTEMS, INC.Inventors: Thomas E. Broome, Verivada (Chandru) Chandrasekaran, John M.K. Daniel, James E. Mayberry