Abstract: A technique facilitates multiple actuations of a toe valve system positioned along a tubing string. According to an embodiment, the toe valve system comprises a piston sleeve slidably disposed in an outer housing which has at least one port therethrough. The toe valve system also may comprise a shifting sleeve shiftable between positions with respect to the at least one port. The piston sleeve may initially be held in a position closing off the at least one port to prevent flow between the interior and exterior of the tubing string. The piston sleeve is held in this closed position via a liquid trapped in a piston chamber which is located between the piston sleeve and the outer housing. The liquid, e.g. oil, is retained in the piston chamber by a release member, e.g. a rupture disc, until sufficient pressure is applied within the toe valve system and against the piston sleeve so as to actuate the release member and to thus allow outflow of liquid from the piston chamber.