Patents by Inventor Chang-Chieh Chen
Chang-Chieh Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210198684Abstract: A method for increasing the yield of microalgae and the yield of a product produced by the microalgae is provided. The method includes performing a change procedure on CAM1 gene and/or calmodulin 1 encoded by the CAM1 gene in a microalga, such that a change occurs in a nucleotide and/or the nucleotide sequence of the CAM1 gene and/or an amino acid and/or the amino acid sequence of the calmodulin 1 encoded by the CAM1 gene in the microalga to obtain an altered microalga. The altered microalga has an altered CAM1 gene and/or an altered calmodulin 1. The altered microalga has a higher growth rate and a higher product production rate and/or yield than an unaltered microalga.Type: ApplicationFiled: December 28, 2020Publication date: July 1, 2021Applicant: Industrial Technology Research InstituteInventors: Chang-Chieh CHEN, Shao-I WU, Jo-Di CHIANG, Yu-Pei LIN, Wen-Chang LU
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Patent number: 10927339Abstract: The present disclosure provides a new mutant of Bacillus thuringiensis which is deposited under Accession number DSM 32419. The present disclosure also provides a method for manufacturing a growth promoter for promoting microalgal cell growth, including: (a) inoculating a mutant of Bacillus thuringiensis into a culturing medium to obtain a bacterial suspension, wherein the mutant of Bacillus thuringiensis is deposited under Accession number DSM 32419; (b) culturing the mutant of Bacillus thuringiensis in the bacterial suspension at least to a stationary phase to obtain a cultured medium of the mutant of Bacillus thuringiensis; and (c) performing a vacuum heating procedure on the cultured medium of the mutant of Bacillus thuringiensis to obtain the growth promoter for promoting microalgal cell growth, wherein the growth promoter for promoting microalgal cell growth contains active substances for promoting microalgal cell growth.Type: GrantFiled: March 16, 2018Date of Patent: February 23, 2021Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Chang-Chieh Chen, Ming-Der Bai, Shao-I Wu, Hsin-Tzu Kuo, Wen-Chang Lu, Hou-Peng Wan
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Publication number: 20180265836Abstract: The present disclosure provides a new mutant of Bacillus thuringiensis which is deposited under Accession number DSM 32419. The present disclosure also provides a method for manufacturing a growth promoter for promoting microalgal cell growth, including: (a) inoculating a mutant of Bacillus thuringiensis into a culturing medium to obtain a bacterial suspension, wherein the mutant of Bacillus thuringiensis is deposited under Accession number DSM 32419; (b) culturing the mutant of Bacillus thuringiensis in the bacterial suspension at least to a stationary phase to obtain a cultured medium of the mutant of Bacillus thuringiensis; and (c) performing a vacuum heating procedure on the cultured medium of the mutant of Bacillus thuringiensis to obtain the growth promoter for promoting microalgal cell growth, wherein the growth promoter for promoting microalgal cell growth contains active substances for promoting microalgal cell growth.Type: ApplicationFiled: March 16, 2018Publication date: September 20, 2018Applicant: Industrial Technology Research InstituteInventors: Chang-Chieh CHEN, Ming-Der BAI, Shao-I WU, Hsin-Tzu KUO, Wen-Chang LU, Hou-Peng WAN
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Publication number: 20170233774Abstract: A method of producing butyric acid, comprising: (a) providing a microorganism co-culture system comprising an air-tight container and the following (1) to (3) contained in the air-tight container: (1) a substrate, comprising a saccharide; (2) at least one of a first strain and a second strain, wherein the first strain is able to fix a carbon oxide and the second strain is able to fermentatively metabolize an amino acid, and wherein the first strain produces a first metabolite in the fermentation, the second strain produces a second metabolite in the fermentation, and each of the first metabolite and the second metabolite comprises acetic acid; and (3) a third strain, being able to metabolize the saccharide, the first metabolite and the second metabolite in the fermentation to produce butyric acid and a metabolic byproduct in fermentation, wherein the metabolic byproduct comprises carbon oxide and hydrogen, wherein, when the second strain is present in the co-culture system, the substrate further comprisesType: ApplicationFiled: February 28, 2017Publication date: August 17, 2017Applicant: Green Cellulosity CorporationInventors: Chang-Chieh CHEN, Cheng-Hao LIU, Shih-Chan TSENG, Ying-Ching SU
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Patent number: 9677097Abstract: An isolated Clostridium cadaveris ITRI04005 and its uses are provided. The isolated Clostridium cadaveris ITRI04005 was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, DSMZ) under the accession number DSM 32078.Type: GrantFiled: July 8, 2015Date of Patent: June 13, 2017Assignee: GREEN CELLULOSITY CORPORATIONInventors: Chiang-Hsiung Tong, Chang-Chieh Chen, Shao-Wen Wu, Shi-Chan Tseng, Hsin-Tzu Wang, Chin-Chen Hsu
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Patent number: 9546406Abstract: A microorganism capable of fixing a carbon oxide and performing fermentation and its preparation method and use are provided, wherein the preparation method comprises: (a) providing a first parental strain which is able to fix a carbon oxide; (b) providing a second parental strain which is able to perform fermentation; (c) preparing a first protoplast and a second protoplast from the first parental strain and the second parental strain, respectively; (d) subjecting the first protoplast and the second protoplast to fuse to provide a fusant; and (e) incubating and selecting the fusant to obtain a target strain. The target strain is useful in the production of an organic compound such as an organic acid and an alcohol, and one embodiment of the target strain is Clostridium tyrobutyricum ITRI02001, deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, DSMZ) under the accession number DSM 32077.Type: GrantFiled: July 8, 2015Date of Patent: January 17, 2017Assignee: GREEN CELLULOSITY CORPORATIONInventors: Chiang-Hsiung Tong, Chang-Chieh Chen, Chin-Chen Hsu, Yi-Te Chou
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Publication number: 20160083755Abstract: An isolated Clostridium cadaveris ITRI04005 and its uses are provided. The isolated Clostridium cadaveris ITRI04005 was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, DSMZ) under the accession number DSM 32078.Type: ApplicationFiled: July 8, 2015Publication date: March 24, 2016Inventors: Chiang-Hsiung TONG, Chang-Chieh CHEN, Shao-Wen WU, Shi-Chan TSENG, Hsin-Tzu WANG, Chin-Chen HSU
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Publication number: 20160076111Abstract: A microorganism capable of fixing a carbon oxide and performing fermentation and its preparation method and use are provided, wherein the preparation method comprises: (a) providing a first parental strain which is able to fix a carbon oxide; (b) providing a second parental strain which is able to perform fermentation; (c) preparing a first protoplast and a second protoplast from the first parental strain and the second parental strain, respectively; (d) subjecting the first protoplast and the second protoplast to fuse to provide a fusant; and (e) incubating and selecting the fusant to obtain a target strain. The target strain is useful in the production of an organic compound such as an organic acid and an alcohol, and one embodiment of the target strain is Clostridium tyrobutyricum ITRI02001, deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, DSMZ) under the accession number DSM 32077.Type: ApplicationFiled: July 8, 2015Publication date: March 17, 2016Inventors: Chiang-Hsiung TONG, Chang-Chieh CHEN, Chin-Chen HSU, Yi-Te CHOU
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Publication number: 20160068919Abstract: A microorganism co-culture system, comprising: (1) a substrate, comprising a saccharide (2) at least one of a first strain and a second strain, wherein the first strain is able to fix a carbon oxide the second strain is able to fermentatively metabolize an amino acid, and wherein the first strain produces a first metabolite in the fermentation, and the second strain produces a second metabolite in the fermentation; and (3) a third strain, being able to metabolize the saccharide, the first metabolite and the second metabolite in the fermentation to produce butyric acid and/or butanol, wherein, when the second strain is present in the co-culture system, the substrate further comprises an amino acid.Type: ApplicationFiled: September 4, 2015Publication date: March 10, 2016Inventors: Chang-Chieh CHEN, Cheng-Hao LIU, Shih-Chan TSENG, Ying-Ching SU
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Patent number: 9200297Abstract: An isolated biologically pure culture of Clostridium tyrobutyricum ITRI04001 or an isolated biologically pure culture of Clostridium tyrobutyricum having the genotypic characteristics of ITRI04001 useful for syngas fermentation. Volatile free acids are produced by a method comprising culturing a microorganism having the genotypic characteristics of ITRI04001 in a medium; providing at least one substrate comprising at least one carbon source chosen from CO and CO2 to the microorganism; and recovering at least one free volatile free acid. Syngas can be the at least one substrate in these processes for producing volatile free acids.Type: GrantFiled: October 2, 2013Date of Patent: December 1, 2015Assignee: GREEN CELLULOSITY CORPORATIONInventors: Chang-Chieh Chen, Yi-Te Chou, Shao-Wen Wu, Shi-Chan Tseng, Hsin-Tzu Kuo, Wan-Ting Ma
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Publication number: 20140193871Abstract: At least one product chosen from acids and alcohols is produced by a microbial fermentation process comprising: providing a gaseous substrate and a liquid medium to a microorganism, wherein the liquid medium comprises lactic acid and/or salts thereof, and wherein the gaseous substrate comprises at least one carbon source chosen from CO and CO2, and allowing the microorganism to produce at least one product chosen from acids and alcohols.Type: ApplicationFiled: December 26, 2013Publication date: July 10, 2014Inventors: Chang-Chieh CHEN, Hsin-Tzu Kuo, Yi-Te Chou, Chin-Chen Hsu, Shao-Wen Wu
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Publication number: 20140120591Abstract: An isolated biologically pure culture of Clostridium tyrobutyricum ITRI04001 or an isolated biologically pure culture of Clostridium tyrobutyricum having the genotypic characteristics of ITRI04001 useful for syngas fermentation. Volatile free acids are produced by a method comprising culturing a microorganism having the genotypic characteristics of ITRI04001 in a medium; providing at least one substrate comprising at least one carbon source chosen from CO and CO2 to the microorganism; and recovering at least one free volatile free acid. Syngas can be the at least one substrate in these processes for producing volatile free acids.Type: ApplicationFiled: October 2, 2013Publication date: May 1, 2014Applicant: Industrial Technology Research InstituteInventors: Chang-Chieh Chen, Yi-Te Chou, Shao-Wen Wu, Shi-Chan Tseng, Hsin-Tzu Kuo, Wan-Ting Ma
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Patent number: 8053219Abstract: The present invention relates to a method of producing polyhydroxyalkanoates (PHAs) using Bacillus sp. with succinate as a carbon source. The PHAs comprise more than 95% of poly(3-hydroxyvalerate-co-4-hydroxyvalerate) (P3HV-co-P4HV).Type: GrantFiled: May 16, 2008Date of Patent: November 8, 2011Assignee: Yuan Ze UniversityInventors: Shih-Hsu Kang, Yi-Ming Sun, Chih-Ching Chien, Shih-Chen Tang, Chang-Chieh Chen
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Publication number: 20080299627Abstract: The present invention relates to a method of producing polyhydroxyalkanoates (PHAs) using Bacillus sp. with succinate as a carbon source. The PHAs comprise more than 95% of poly(3-hydroxyvalerate-co-4-hydroxyvalerate) (P3HV-co-P4HV).Type: ApplicationFiled: May 16, 2008Publication date: December 4, 2008Applicant: YUAN ZE UNIVERSITYInventors: Shih-Hsu Kang, Yi-Ming Sun, Chih-Ching Chien, Shih-Chen Tang, Chang-Chieh Chen