Patents by Inventor Chang-Chieh Chen

Chang-Chieh Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210198684
    Abstract: A method for increasing the yield of microalgae and the yield of a product produced by the microalgae is provided. The method includes performing a change procedure on CAM1 gene and/or calmodulin 1 encoded by the CAM1 gene in a microalga, such that a change occurs in a nucleotide and/or the nucleotide sequence of the CAM1 gene and/or an amino acid and/or the amino acid sequence of the calmodulin 1 encoded by the CAM1 gene in the microalga to obtain an altered microalga. The altered microalga has an altered CAM1 gene and/or an altered calmodulin 1. The altered microalga has a higher growth rate and a higher product production rate and/or yield than an unaltered microalga.
    Type: Application
    Filed: December 28, 2020
    Publication date: July 1, 2021
    Applicant: Industrial Technology Research Institute
    Inventors: Chang-Chieh CHEN, Shao-I WU, Jo-Di CHIANG, Yu-Pei LIN, Wen-Chang LU
  • Patent number: 10927339
    Abstract: The present disclosure provides a new mutant of Bacillus thuringiensis which is deposited under Accession number DSM 32419. The present disclosure also provides a method for manufacturing a growth promoter for promoting microalgal cell growth, including: (a) inoculating a mutant of Bacillus thuringiensis into a culturing medium to obtain a bacterial suspension, wherein the mutant of Bacillus thuringiensis is deposited under Accession number DSM 32419; (b) culturing the mutant of Bacillus thuringiensis in the bacterial suspension at least to a stationary phase to obtain a cultured medium of the mutant of Bacillus thuringiensis; and (c) performing a vacuum heating procedure on the cultured medium of the mutant of Bacillus thuringiensis to obtain the growth promoter for promoting microalgal cell growth, wherein the growth promoter for promoting microalgal cell growth contains active substances for promoting microalgal cell growth.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: February 23, 2021
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Chang-Chieh Chen, Ming-Der Bai, Shao-I Wu, Hsin-Tzu Kuo, Wen-Chang Lu, Hou-Peng Wan
  • Publication number: 20180265836
    Abstract: The present disclosure provides a new mutant of Bacillus thuringiensis which is deposited under Accession number DSM 32419. The present disclosure also provides a method for manufacturing a growth promoter for promoting microalgal cell growth, including: (a) inoculating a mutant of Bacillus thuringiensis into a culturing medium to obtain a bacterial suspension, wherein the mutant of Bacillus thuringiensis is deposited under Accession number DSM 32419; (b) culturing the mutant of Bacillus thuringiensis in the bacterial suspension at least to a stationary phase to obtain a cultured medium of the mutant of Bacillus thuringiensis; and (c) performing a vacuum heating procedure on the cultured medium of the mutant of Bacillus thuringiensis to obtain the growth promoter for promoting microalgal cell growth, wherein the growth promoter for promoting microalgal cell growth contains active substances for promoting microalgal cell growth.
    Type: Application
    Filed: March 16, 2018
    Publication date: September 20, 2018
    Applicant: Industrial Technology Research Institute
    Inventors: Chang-Chieh CHEN, Ming-Der BAI, Shao-I WU, Hsin-Tzu KUO, Wen-Chang LU, Hou-Peng WAN
  • Publication number: 20170233774
    Abstract: A method of producing butyric acid, comprising: (a) providing a microorganism co-culture system comprising an air-tight container and the following (1) to (3) contained in the air-tight container: (1) a substrate, comprising a saccharide; (2) at least one of a first strain and a second strain, wherein the first strain is able to fix a carbon oxide and the second strain is able to fermentatively metabolize an amino acid, and wherein the first strain produces a first metabolite in the fermentation, the second strain produces a second metabolite in the fermentation, and each of the first metabolite and the second metabolite comprises acetic acid; and (3) a third strain, being able to metabolize the saccharide, the first metabolite and the second metabolite in the fermentation to produce butyric acid and a metabolic byproduct in fermentation, wherein the metabolic byproduct comprises carbon oxide and hydrogen, wherein, when the second strain is present in the co-culture system, the substrate further comprises
    Type: Application
    Filed: February 28, 2017
    Publication date: August 17, 2017
    Applicant: Green Cellulosity Corporation
    Inventors: Chang-Chieh CHEN, Cheng-Hao LIU, Shih-Chan TSENG, Ying-Ching SU
  • Patent number: 9677097
    Abstract: An isolated Clostridium cadaveris ITRI04005 and its uses are provided. The isolated Clostridium cadaveris ITRI04005 was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, DSMZ) under the accession number DSM 32078.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: June 13, 2017
    Assignee: GREEN CELLULOSITY CORPORATION
    Inventors: Chiang-Hsiung Tong, Chang-Chieh Chen, Shao-Wen Wu, Shi-Chan Tseng, Hsin-Tzu Wang, Chin-Chen Hsu
  • Patent number: 9546406
    Abstract: A microorganism capable of fixing a carbon oxide and performing fermentation and its preparation method and use are provided, wherein the preparation method comprises: (a) providing a first parental strain which is able to fix a carbon oxide; (b) providing a second parental strain which is able to perform fermentation; (c) preparing a first protoplast and a second protoplast from the first parental strain and the second parental strain, respectively; (d) subjecting the first protoplast and the second protoplast to fuse to provide a fusant; and (e) incubating and selecting the fusant to obtain a target strain. The target strain is useful in the production of an organic compound such as an organic acid and an alcohol, and one embodiment of the target strain is Clostridium tyrobutyricum ITRI02001, deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, DSMZ) under the accession number DSM 32077.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: January 17, 2017
    Assignee: GREEN CELLULOSITY CORPORATION
    Inventors: Chiang-Hsiung Tong, Chang-Chieh Chen, Chin-Chen Hsu, Yi-Te Chou
  • Publication number: 20160083755
    Abstract: An isolated Clostridium cadaveris ITRI04005 and its uses are provided. The isolated Clostridium cadaveris ITRI04005 was deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, DSMZ) under the accession number DSM 32078.
    Type: Application
    Filed: July 8, 2015
    Publication date: March 24, 2016
    Inventors: Chiang-Hsiung TONG, Chang-Chieh CHEN, Shao-Wen WU, Shi-Chan TSENG, Hsin-Tzu WANG, Chin-Chen HSU
  • Publication number: 20160076111
    Abstract: A microorganism capable of fixing a carbon oxide and performing fermentation and its preparation method and use are provided, wherein the preparation method comprises: (a) providing a first parental strain which is able to fix a carbon oxide; (b) providing a second parental strain which is able to perform fermentation; (c) preparing a first protoplast and a second protoplast from the first parental strain and the second parental strain, respectively; (d) subjecting the first protoplast and the second protoplast to fuse to provide a fusant; and (e) incubating and selecting the fusant to obtain a target strain. The target strain is useful in the production of an organic compound such as an organic acid and an alcohol, and one embodiment of the target strain is Clostridium tyrobutyricum ITRI02001, deposited at German Collection of Microorganisms and Cell Cultures (Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, DSMZ) under the accession number DSM 32077.
    Type: Application
    Filed: July 8, 2015
    Publication date: March 17, 2016
    Inventors: Chiang-Hsiung TONG, Chang-Chieh CHEN, Chin-Chen HSU, Yi-Te CHOU
  • Publication number: 20160068919
    Abstract: A microorganism co-culture system, comprising: (1) a substrate, comprising a saccharide (2) at least one of a first strain and a second strain, wherein the first strain is able to fix a carbon oxide the second strain is able to fermentatively metabolize an amino acid, and wherein the first strain produces a first metabolite in the fermentation, and the second strain produces a second metabolite in the fermentation; and (3) a third strain, being able to metabolize the saccharide, the first metabolite and the second metabolite in the fermentation to produce butyric acid and/or butanol, wherein, when the second strain is present in the co-culture system, the substrate further comprises an amino acid.
    Type: Application
    Filed: September 4, 2015
    Publication date: March 10, 2016
    Inventors: Chang-Chieh CHEN, Cheng-Hao LIU, Shih-Chan TSENG, Ying-Ching SU
  • Patent number: 9200297
    Abstract: An isolated biologically pure culture of Clostridium tyrobutyricum ITRI04001 or an isolated biologically pure culture of Clostridium tyrobutyricum having the genotypic characteristics of ITRI04001 useful for syngas fermentation. Volatile free acids are produced by a method comprising culturing a microorganism having the genotypic characteristics of ITRI04001 in a medium; providing at least one substrate comprising at least one carbon source chosen from CO and CO2 to the microorganism; and recovering at least one free volatile free acid. Syngas can be the at least one substrate in these processes for producing volatile free acids.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: December 1, 2015
    Assignee: GREEN CELLULOSITY CORPORATION
    Inventors: Chang-Chieh Chen, Yi-Te Chou, Shao-Wen Wu, Shi-Chan Tseng, Hsin-Tzu Kuo, Wan-Ting Ma
  • Publication number: 20140193871
    Abstract: At least one product chosen from acids and alcohols is produced by a microbial fermentation process comprising: providing a gaseous substrate and a liquid medium to a microorganism, wherein the liquid medium comprises lactic acid and/or salts thereof, and wherein the gaseous substrate comprises at least one carbon source chosen from CO and CO2, and allowing the microorganism to produce at least one product chosen from acids and alcohols.
    Type: Application
    Filed: December 26, 2013
    Publication date: July 10, 2014
    Inventors: Chang-Chieh CHEN, Hsin-Tzu Kuo, Yi-Te Chou, Chin-Chen Hsu, Shao-Wen Wu
  • Publication number: 20140120591
    Abstract: An isolated biologically pure culture of Clostridium tyrobutyricum ITRI04001 or an isolated biologically pure culture of Clostridium tyrobutyricum having the genotypic characteristics of ITRI04001 useful for syngas fermentation. Volatile free acids are produced by a method comprising culturing a microorganism having the genotypic characteristics of ITRI04001 in a medium; providing at least one substrate comprising at least one carbon source chosen from CO and CO2 to the microorganism; and recovering at least one free volatile free acid. Syngas can be the at least one substrate in these processes for producing volatile free acids.
    Type: Application
    Filed: October 2, 2013
    Publication date: May 1, 2014
    Applicant: Industrial Technology Research Institute
    Inventors: Chang-Chieh Chen, Yi-Te Chou, Shao-Wen Wu, Shi-Chan Tseng, Hsin-Tzu Kuo, Wan-Ting Ma
  • Patent number: 8053219
    Abstract: The present invention relates to a method of producing polyhydroxyalkanoates (PHAs) using Bacillus sp. with succinate as a carbon source. The PHAs comprise more than 95% of poly(3-hydroxyvalerate-co-4-hydroxyvalerate) (P3HV-co-P4HV).
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: November 8, 2011
    Assignee: Yuan Ze University
    Inventors: Shih-Hsu Kang, Yi-Ming Sun, Chih-Ching Chien, Shih-Chen Tang, Chang-Chieh Chen
  • Publication number: 20080299627
    Abstract: The present invention relates to a method of producing polyhydroxyalkanoates (PHAs) using Bacillus sp. with succinate as a carbon source. The PHAs comprise more than 95% of poly(3-hydroxyvalerate-co-4-hydroxyvalerate) (P3HV-co-P4HV).
    Type: Application
    Filed: May 16, 2008
    Publication date: December 4, 2008
    Applicant: YUAN ZE UNIVERSITY
    Inventors: Shih-Hsu Kang, Yi-Ming Sun, Chih-Ching Chien, Shih-Chen Tang, Chang-Chieh Chen