Patents by Inventor Chang Gyu Heo

Chang Gyu Heo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Marker comprising anti-CK8/18 complex autoantibody and its use for diagnosing cancer
    Patent number: 9234893
    Abstract: The present invention relates to a cytokeratin 8/18 complex-specific autoantibody or a fragment comprising an antigen-binding site (paratope) thereof, the use thereof in the diagnosis of breast cancer, a polypeptide having an amino acid sequence of an epitope specifically binding to the autoantibody, a composition for diagnosing breast cancer comprising an agent capable of measuring an expression level of the autoantibody or the fragment comprising an antigen-binding site thereof, a hybridoma cell line producing the autoantibody, and a kit for diagnosing breast cancer comprising the composition of the present invention. Further, the present invention relates to a method for diagnosing breast cancer, comprising the step of detecting the cytokeratin 8/18 complex-specific autoantibody or the fragment comprising the antigen-binding site thereof using the composition of the present invention, and a method for screening a therapeutic agent for breast cancer using the autoantibody.
    Type: Grant
    Filed: February 20, 2012
    Date of Patent: January 12, 2016
    Inventors: Eun Wie Cho, Chang Gyu Heo, Jeong Heon Ko, Mi Kyung Woo, Hyang Sook Yoo, Hai Min Hwang
  • MARKER COMPRISING ANTI-CK8/18 COMPLEX AUTOANTIBODY AND ITS USE FOR DIAGNOSING CANCER
    Publication number: 20140093892
    Abstract: The present invention relates to a cytokeratin 8/18 complex-specific autoantibody or a fragment comprising an antigen-binding site (paratope) thereof, the use thereof in the diagnosis of breast cancer, a polypeptide having an amino acid sequence of an epitope specifically binding to the autoantibody, a composition for diagnosing breast cancer comprising an agent capable of measuring an expression level of the autoantibody or the fragment comprising an antigen-binding site thereof, a hybridoma cell line producing the autoantibody, and a kit for diagnosing breast cancer comprising the composition of the present invention. Further, the present invention relates to a method for diagnosing breast cancer, comprising the step of detecting the cytokeratin 8/18 complex-specific autoantibody or the fragment comprising the antigen-binding site thereof using the composition of the present invention, and a method for screening a therapeutic agent for breast cancer using the autoantibody.
    Type: Application
    Filed: February 20, 2012
    Publication date: April 3, 2014
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Eun Wie Cho, Chang Gyu Heo, Jeong Heon Ko, Mi Kyung Woo, Hyang Sook Yoo, Hai Min Hwang