Patents by Inventor Chang H. Paik

Chang H. Paik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of stably radiolabeling antibodies with technetium and rhenium
    Patent number: 4652440
    Abstract: .sup.99 m Tc-labeling of antibodies and antibody fragments, either unconjugated or conjugated to DTPA, is effected in the presence of molar excess of free or carrier-bound DTPA to substantially completely inhibit direct technetium binding to non-stable binding sites on the antibody. The resultant .sup.99m Tc-labeled antibody has a stable label and is useful for, inter alia, tumor imaging by gamma scintigraphy and/or tumor therapy. Rhenium-labeling can be similarly effected.
    Type: Grant
    Filed: May 3, 1984
    Date of Patent: March 24, 1987
    Inventors: Chang H. Paik, Richard C. Reba, William C. Eckelman