Patents by Inventor Chang-Hoe Ku

Chang-Hoe Ku has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing terbinafine and HCI salt thereof
    Patent number: 6689913
    Abstract: Provided is a process for preparing terbinafine or its HCl salt comprising: reacting a furan derivative with a base to form a second compound; performing a reductive alkylation of the second compound obtained in the step with N-methyl-1-naphthalenemethylamine or its HCl salt to form a third compound; and purifying the third compound.
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: February 10, 2004
    Assignee: Yuhan Corporation
    Inventors: Tai-Au Lee, Kyu-Jung Wang, Hong-Bae Kim, Kyoung-Chan Kwon, Chang-Hoe Ku
  • Process for preparing terbinafine and HCI salt thereof
    Publication number: 20030130530
    Abstract: Provided are a process for preparing terbinafine or its HCl salt, which comprises: (a) reacting a furan derivative with a base; (b) performing a reductive alkylation of the resulting compound obtained in the step (a) with N-methyl-1-naphthalenemethylamine or its HCl salt; and (c) purifying the resulting compound obtained in the step (b).
    Type: Application
    Filed: December 27, 2002
    Publication date: July 10, 2003
    Inventors: Tai-Au Lee, Kyu-Jung Wang, Hong-Bae Kim, Kyoung-Chan Kwon, Chang-Hoe Ku