Abstract: One aspect of the disclosure relates to a cargo delivery system comprising an autophagy targeting ligand and a target-binding ligand. In one aspect of the disclosure, by comprising an autophagy targeting ligand, cargo, which is a target-binding ligand that specifically binds to a target, is delivered to the p62 protein and autophagy is activated, so that depending on the type of target-binding ligand used, a target to be degraded can be selectively and directly removed. Accordingly, the cargo delivery system according to an aspect of the disclosure may be used in pharmaceutical compositions or food compositions for preventing, alimerating, and treating various diseases.

Abstract: Provided is a coil substrate having an asymmetric structure, in which the area of a coil pattern included in a first region is expanded relative to the area of a coil pattern included in a second region with respect to a virtual axis, and an electronic apparatus having the same. The coil substrate comprises a base layer; and a coil pattern spirally wound on the base layer, wherein an upper portion of the base layer is divided into a first region and a second region based on a void region formed inside the coil pattern, wherein an area of the coil pattern formed in the second region is larger than an area of the coil pattern formed in the first region.

Abstract: The present specification relates to a compound as a UBR box domain ligand. The present specification provides a small molecule compound that binds to the UBR box domain. Further, the present specification provides a composition for inhibiting UBR box domain substrate binding, including a ligand compound that binds to a UBR box domain, a pharmaceutical composition for treating UBR-related disease, and a use thereof.

Abstract: The present specification relates to a compound as a UBR box domain ligand. The present specification provides a small molecule compound that binds to the UBR box domain. Further, the present specification provides a composition for inhibiting UBR box domain substrate binding, including a ligand compound that binds to a UBR box domain, a pharmaceutical composition for treating UBR-related disease, and a use thereof.

Abstract: Disclosed are an artificial leather for crash pads and a crash pad manufactured using the same. The artificial leather for crash pads may have improved workability when workers directly cover a crash pad with the artificial leather for crash pads and require reduced manufacturing costs by using a textile substrate layer made of a circular knit fabric that satisfies a specific physical property range.

Abstract: Provided is a syringe formulation that is pre-filled with botulinum toxin, which allows easy control of a discharge rate and may be stable.

Abstract: According to an embodiment, provided is a Bluetooth device comprising a master module and at least one slave module, wherein: the master module operates in an active mode when a mobile communication device is located within a pre-set range and switches to a power saving mode when the mobile communication device deviates from the pre-set range; in the active mode, the master module performs data communication by being connected to the mobile communication device located within the pre-set range and operates the Bluetooth device by periodically exchanging a packet with the slave module; and in the power saving mode, the master module operates in at least one of a first mode in which a packet exchange cycle with the slave module is adjusted from a first interval to a second interval, and a second mode in which a connection between the master module and the slave module is released.

Abstract: A system for providing golf information, the system which includes a green photographing unit for photographing an image of an area including a green on a golf course and communicatively connected to a communication network to transmit green image data to an outside, a golfer terminal that is carried by a golfer on the golf course and communicatively connected to a communication network to transmit golfer position data to the outside, and an information providing server that is communicatively connected to the communication network to generate golf information using the green image data and the golfer position data and transmit the generated golf information to the golfer terminal.

Abstract: An elastic material vibration test apparatus includes a lower support plate having an upper surface on which an elastic material to be tested is placed, an upper support plate disposed above the lower support plate to be spaced apart from the lower support plate, a pillar connecting the lower support plate and the upper support plate, a pressing rod configured to pass through the upper support plate and ascend and descend in a vertical direction, an air bearing installed on the upper support plate and supporting an outer surface of the pressing rod in a non-contact state, a pressing plate coupled to a lower end of the pressing rod to press an upper surface of the elastic material, and one or more weights coupled to the pressing rod above the air bearing.

Abstract: A seat automatic arrangement method and apparatus of an autonomous driving vehicle is provided. The seat automatic arrangement method and apparatus have an advantage that it is possible to automatically arrange seats in the vehicle into the seat-facing mode through remote control, and it is possible to prevent interference when moving the seats by arranging the seats in accordance with priority when arranging the seats into the seat-facing mode, thereby being able to more smoothly arrange the seats into the seat-facing mode in an autonomous driving vehicle.

Abstract: A pharmaceutical or food composition including alverine, 4-hydroxy alverine, a derivative thereof, or a salt thereof and their uses are disclosed. The composition is useful for preventing, alleviating, or treating muscular weakness-related diseases. When myoblasts are treated with the alverine, 4-hydroxy alverine, derivative thereof, or salt thereof, differentiation into myotubes is promoted. Therefore, the alverine, 4-hydroxy alverine, derivative thereof, or salt thereof can be effectively used in the promotion of differentiation of myoblasts and the prevention, alleviation, or treatment of muscular weakness-related diseases.

Abstract: A light emitting diode, including a first type semiconductor layer, an active layer, and a second type semiconductor layer; an ohmic contact layer disposed on the second type semiconductor layer; a first insulating layer disposed on the semiconductor structure and including a first opening overlapping the first type semiconductor layer and a second opening overlapping the ohmic contact layer; a first connection wiring disposed on the first insulating layer, the first connection wiring having a first portion and a second portion; and a second connection wiring disposed on the first insulating layer and spaced apart from the first connection wiring, the second connection wiring electrically connected to the second type semiconductor layer through the second opening. The second connection wiring surrounds at least a portion of the first portion of the first connection wiring in a plan view.

Abstract: The invention relates to the use of an animal-protein-free botulinum toxin composition to treat a disease, disorder or condition in a patient in need thereof whereby the animal-protein-free botulinum toxin composition exhibits a longer lasting effect in the patient compared to an animal-protein-containing botulinum toxin composition.

Abstract: A port blocking module of an electronic device and a port locking apparatus having the same includes a module frame which is formed to correspond to size and shape of a port of an electronic device, a locking module having a locking module body fixedly installed inside the module frame, a first locking member connected to the locking module body to be elastically transformable such that the first locking member selectively comes into contact with a terminal part inside the port, and a second locking member connected to the locking module body to be elastically transformable such that the second locking member is disposed by being spaced apart from the first locking member, and a pattern module which is installed to be movable between a locking position and an unlocking position inside and outside the module frame.

Abstract: Disclosed is a direct slot cooling system for motors, including a stator configured to expand an inner slot space of a stator core where a coil is wound to form a cooling slot through which a cooling fluid passes; a rotor coupled to a center of the stator to rotate; and a housing coupled to left and right sides of the stator to form a cooling jacket in watertight communication with a cooling slot so that a cooling fluid circulates in the cooling jacket.

Abstract: An unlocking key for a port lock of an electronic device for unlocking and separating, from a port of the electronic device, a blocking module which is inserted and coupled to the port of the electronic device and has a key recess in which a pattern part and a latch key holding recess are formed on different inner surfaces of the key recess, includes a main body casing, a movable housing installed to protrude from a front end of the main body casing, a pattern key which is fixedly installed to protrude from a front end of the movable housing, a latch key which protrudes from the front end of the movable housing, and a manipulation part which is movably installed in the main body casing and controls reciprocating of the movable housing and opening and closing of the latch key.

Abstract: The present invention relates to a method for preparing a biomaterial having selectively functionalized tyrosine, a biomaterial having selectively functionalized tyrosine, and a pharmaceutical composition containing the same as an active ingredient. The method for preparing a biomaterial to which a compound represented by formula 2 is coupled, of the present invention, allows the compound represented by formula 2 to be selectively coupled, in a high yield in a biomaterial, to tyrosine, which is present on the surface of an aqueous solution such that the coupling thereof to amino acids other than tyrosine does not occur and, when only one tyrosine is present, heterogeneous mixtures are not present and the inherent activity of the biomaterial is maintained, and thus the compound can be effectively used as a pharmaceutical composition containing a biomaterial drug as an active ingredient.

Abstract: The present disclosure relates to an antifouling coating layer, and in detail, provides a method of manufacturing an antifouling coating layer having excellent antifouling characteristic and durability through quick deposition using iCVD.

Abstract: The present disclosure relates to a visible and infrared stealth element. The element of the present disclosure may selectively control thermal radiation energy according to a wavelength, and may also control a surface color and reflectance of near-infrared light and short-wavelength infrared light.