Patents by Inventor Chang-Kyun Han

Chang-Kyun Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8158168
    Abstract: The present invention relates to a Momordicae semen extract effective in the prevention and treatment of gastritis or gastric ulcer and momordica saponin I isolated therefrom. The Momordicae semen extract and the momordica saponin I isolated therefrom is effective in the prevention and treatment of gastritis or gastric ulcer since they prevent the damage of the gastric mucosa caused by alcohols and inhibit the secretion of gastric acid.
    Type: Grant
    Filed: August 16, 2010
    Date of Patent: April 17, 2012
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Bong Cheol Kim, Joo Hyon Kim, Se Jun Yun, Eun Jung Noh, Gi Uk Jang, Chang-Kyun Han, Yong-Baik Cho, Wie-Jong Kwak
  • Publication number: 20120070517
    Abstract: The present invention relates to a novel use of herbal extracts in a pharmaceutical composition for prevention and treatment of nephritis and, more particularly, to a pharmaceutical composition and a health functional food for prevention and/or treatment of nephritis that contains at least one herbal extract selected from the group consisting of a Crataegi Fructus extract, a Cinnamomi Cortex extract, a Prunella Spica extract, and an Equiseti Herba extract, a method for prevention and/or treatment of nephritis using the herbal extract, and a use of the herbal extract in preparation of a composition for prevention and/or treatment of nephritis. The herbal extract has a good therapeutic effect for nephritis on a nephritis model of which the nephritis is induced by a drug such as gentamicin, cisplatin, etc., and a good inhibitory activity on the growth of mesangial cells in kidneys, thereby providing a very useful means for prevention and/or treatment of nephritis.
    Type: Application
    Filed: June 1, 2010
    Publication date: March 22, 2012
    Inventors: Jin Auh, Chang-Hwan Kim, Chang-Kyun Han, Sung-Hum Yeon, Seung-In Choe, Young-June Shin, Dong-Oh Han, Soo-Im Chang, Ji-Hye Lee, Jun-Seok Lee, Ho-Young Kwak, Hyo-Jin Moon, Jong-Wook Lee, Sung-Min Kim
  • Publication number: 20110081434
    Abstract: A composition for suppressing cough, removing sputum, preventing and/or treating a respiratory disease comprising an extract of Coptidis rhizoma or a combined extract of Coptidis rhizoma with ivy leaf as an active ingredient, and a method of suppressing cough, removing sputum, and/or preventing and/or treating respiratory disease using the composition, are provided.
    Type: Application
    Filed: June 12, 2009
    Publication date: April 7, 2011
    Applicant: Ahn-Gook Pharmaceutical Co. LTd
    Inventors: Jin Auh, Chang-Hwan Kim, Chang-Kyun Han, Sung-Hum Yeon, Young-June Shin, Min-Ki Shin, Soo-Im Chang
  • Patent number: 7919127
    Abstract: This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.
    Type: Grant
    Filed: February 3, 2005
    Date of Patent: April 5, 2011
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Wonrack Choi, Chang-Kyun Han, Jung-Woo Seo, Guang-Jin Im, ChilMann Jung, Se Jun Yun, Wie-Jong Kwak, Tae Kon Kim, bongcheol Kim, Soomin Lee
  • Publication number: 20100310687
    Abstract: The present invention relates to a Momordicae semen extract effective in the prevention and treatment of gastritis or gastric ulcer and momordica saponin I isolated therefrom. The Momordicae semen extract and the momordica saponin I isolated therefrom is effective in the prevention and treatment of gastritis or gastric ulcer since they prevent the damage of the gastric mucosa caused by alcohols and inhibit the secretion of gastric acid.
    Type: Application
    Filed: August 16, 2010
    Publication date: December 9, 2010
    Applicant: SK Chemicals Co., Ltd.
    Inventors: Bong Cheol KIM, Joo Hyon Kim, Se Jun Yun, Eun Jung Noh, Gi Uk Jang, Chang-Kyun Han, Yong-Baik Cho, Wie-Jong Kwak
  • Publication number: 20100221371
    Abstract: The present invention relates to an extract isolated from Sophorae Radix useful for prevention and treatment of respiratory diseases. More specifically, the present invention relates to a pharmaceutical drug comprising the Sophorae Radix extract having excellent effects of inhibiting airway contraction, respiratory infections, 5-lipoxygenase activity, phosphodiesterase 4 activity, airway hyper-responsiveness and airway remodeling; antagonistic activity against leukotriene D4; and an antitussive effect, thus being useful for prevention and treatment of respiratory diseases such as asthma, acute or chronic bronchitis, allergic rhinitis, acute upper respiratory infections and acute lower respiratory infections, and the like.
    Type: Application
    Filed: May 12, 2010
    Publication date: September 2, 2010
    Inventors: Chang-Kyun HAN, Kiwon Joung, Hunseung Yoo, Yong-Baik Cho, Keun Ho Ryu, Hye Yeon Baek, Taek-Soo Kim, In Ho Jung, Wie-Jong Kwak
  • Publication number: 20100190968
    Abstract: The present invention relates to the use of oleanane-type triterpene saponin compounds, which are effective for improving memory and learning ability, as an effective ingredient of drugs for the treatment and prevention of dementia and mild cognitive impairment and health foods for the improvement of brain functions including cognitive function.
    Type: Application
    Filed: October 24, 2006
    Publication date: July 29, 2010
    Inventors: Bong Cheol Kim, Wonrack Choi, Soo Min Lee, Se Jun Yun, Chang-Kyun Han, Guang-Jin Im, Wie-Jong Kwak
  • Publication number: 20100099763
    Abstract: The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
    Type: Application
    Filed: December 21, 2009
    Publication date: April 22, 2010
    Inventors: Wonrack CHOI, Chang-Kyun Han, Tae Kon Kim, Guang-Jin Im, Chil Mann Jung, Se Jun Yun, Bongcheol Kim, Soomin Lee, Wie-Jong Kwak
  • Patent number: 7695741
    Abstract: Disclosed is a topical formulation for preventing or treating acne, in particular to a topical formulation for preventing or treating acne through the antimicrobial activity of the formulation against acne-causing bacteria, Propionibacterium acnes, inhibition of excess production of sebum by inhibition of excess production of sebum by inhibition of 5?-reductase, inhibition of comedo, keratolysis and anti-inflammatory action, which comprises extract obtained from at least one oriental medicine selected from the group consisting of Cavalia gladiata, Biota orientalis and Coptis chinensis.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: April 13, 2010
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Soon Keun Lee, Wie-Jong Kwak, Chang-Kyun Han, Joo Hyon Kim
  • Publication number: 20090004309
    Abstract: The present invention relates to a Momordicae semen extract effective in the prevention and treatment of gastritis or gastric ulcer and momordica saponin I isolated therefrom. The Momordicae semen extract and the momordica saponin I isolated therefrom is effective in the prevention and treatment of gastritis or gastric ulcer since they prevent the damage of the gastric mucosa caused by alcohols and inhibit the secretion of gastric acid.
    Type: Application
    Filed: December 20, 2006
    Publication date: January 1, 2009
    Inventors: Bong Cheol Kim, Joo Hyon Kim, Se Jun Yun, Eun Jung Noh, Gi Uk Jang, Chang-Kyun Han, Yong-Baik Cho, Wie-Jong Kwak
  • Publication number: 20080248143
    Abstract: This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.
    Type: Application
    Filed: February 3, 2005
    Publication date: October 9, 2008
    Inventors: Wonrack Choi, Chang-Kyun Han, Jung-Woo Seo, Guang-Jin Im, Chilmann Jung, Se Jun Yun, Wie-Jong Kwak, Tae Kon Kim, Bongcheol Kim, Soomin Lee
  • Publication number: 20080107757
    Abstract: The present invention relates to an extract isolated from Sophorae Radix useful for prevention and treatment of respiratory diseases. More specifically, the present invention relates to a pharmaceutical drug comprising the Sophorae Radix extract having excellent effects of inhibiting airway contraction, respiratory infections, 5-lipoxygenase activity, phosphodiesterase 4 activity, airway hyper-responsiveness and airway remodeling; antagonistic activity against leukotriene D4; and an antitussive effect, thus being useful for prevention and treatment of respiratory diseases such as asthma, acute or chronic bronchitis, allergic rhinitis, acute upper respiratory infections and acute lower respiratory infections, and the like.
    Type: Application
    Filed: October 21, 2005
    Publication date: May 8, 2008
    Inventors: Chang-Kyun Han, Kiwon Joung, Hunseung Yoo, Yong-Baik Cho, Keun Ho Ryu, Hye Yeon Baek, Taek-Soo Kim, In Ho Jung, Wie-Jong Kwak
  • Patent number: 7314644
    Abstract: Disclosed is a method for extracting and purifying active constituents from honeysuckle (Lonicera japonica Thunb.) and its use. More particularly, this invention relates to an extraction and purification method of active constituents including sweroside from for honeysuckle stem (stem of honeysuckle where leaves are removed) by removing tannins, hardly soluble flavonoids, saponins, and the like. Thus obtained active constituents have better anti-inflammatory and analgesic effect, are safer and more stable than the conventional active constituents obtained from honeysuckle flower or honeysuckle leaves, and include sweroside which is an effective active ingredient of anti-inflammatory and analgesic drug.
    Type: Grant
    Filed: September 8, 2003
    Date of Patent: January 1, 2008
    Assignee: SK Chemicals Co., Ltd.
    Inventors: Wie-Jong Kwak, Yong-Baik Cho, Chang-Kyun Han, Hee Jae Shin, Keun Ho Ryu, Hunseung Yoo, Hae In Rhee
  • Publication number: 20070249711
    Abstract: The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.
    Type: Application
    Filed: October 11, 2004
    Publication date: October 25, 2007
    Inventors: Wonrack Choi, Chang-Kyun Han, Tae Kim, Guang-Jin Im, Chil Jung, Se Yun, Bongcheol Kim, Soomin Lee, Wie-Jong Kwak
  • Publication number: 20070111955
    Abstract: Disclosed is a method for extracting and purifying active constituents from honeysuckle (Lonicera japonica Thunb.) and its use. More particularly, this invention relates to an extraction and purification method of active constituents including sweroside from for honeysuckle stem (stem of honeysuckle where leaves are removed) by removing tannins, hardly soluble flavonoids, saponins, and the like. Thus obtained active constituents have better anti-inflammatory and analgesic effect, are safer and more stable than the conventional active constituents obtained from honeysuckle flower or honeysuckle leaves, and include sweroside which is an effective active ingredient of anti-inflammatory and analgesic drug.
    Type: Application
    Filed: January 11, 2007
    Publication date: May 17, 2007
    Inventors: Wie-Jong Kwak, Yong-Baik Cho, Chang-Kyun Han, Hee Shin, Keun Ryu, Hunseung Yoo, Hae Rhee
  • Publication number: 20060014240
    Abstract: Disclosed is a method for extracting and purifying active constituents from honeysuckle (Lonicera japonica Thunb.) and its use. More particularly, this invention relates to an extraction and purification method of active constituents including sweroside from for honeysuckle stem (stem of honeysuckle where leaves are removed) by removing tannins, hardly soluble flavonoids, saponins, and the like. Thus obtained active constituents have better anti-inflammatory and analgesic effect, are safer and more stable than the conventional active constituents obtained from honeysuckle flower or honeysuckle leaves, and include sweroside which is an effective active ingredient of anti-inflammatory and analgesic drug.
    Type: Application
    Filed: September 8, 2003
    Publication date: January 19, 2006
    Inventors: Wie-Jong Kwak, Yong-Baik Cho, Chang-Kyun Han, Hee Shin, Keun Ryu, Hunseung Yoo, Hai Rhee
  • Publication number: 20050271750
    Abstract: Disclosed is a topical formulation for preventing or treating acne, in particular to a topical formulation for preventing or treating acne through the antimicrobial activity of the formulation against acne-causing bacteria, Propionibacterium acnes, inhibition of excess production of sebum by inhibition of excess production of sebum by inhibition of 5?-reductase, inhibition of comedo, keratolysis and anti-inflammatory action, which comprises extract obtained from at least one oriental medicine selected from the group consisting of Cavalia gladiata, Biota orientalis and Coptis chinensis.
    Type: Application
    Filed: August 12, 2003
    Publication date: December 8, 2005
    Inventors: Soon Lee, Wie-Jong Kwak, Chang-Kyun Han, Joo Kim
  • Publication number: 20040146593
    Abstract: The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.
    Type: Application
    Filed: November 17, 2003
    Publication date: July 29, 2004
    Inventors: Chang-Kyun Han, Wie-Jong Kwak, Ki Won Joung, Hun Seung Yoo, Do Seung Kum, Yong-Baik Cho, Keun Ho Ryu, Hae In Rhee, Taek Su Kim, In Ho Jung, So Yoon Lee, Jung Bum Yi, Joo-Hyon Kim, Key An Um
  • Patent number: 5910307
    Abstract: This invention to a process of extracting and purifying biologically effective ingredients from combined medicinal plants and their plant extract composition and more particularly, to a process for effective extracting and purifying the biologically effective ingredients by mixing Clematis Radix, Trichosanthes root and Prunella Herba in a certain ratio, being useful for alleviating acute/chronic inflammation and also for inhibiting platelet/whole blood aggregation, abnormally proliferated immunocytes (e.g., B-lymphocyte, T-lymphocyte), inflammation-inducing enzymes (5-Lipoxygenase, Cyclooxygenase-I, Cyclooxygenase-II) and also scavenging activity on toxic active oxygen species when compared to a single plant extracts, together with their extract composition, which may be effectively used as an anti-inflammatory agent with analgesic effects, rheumatoid arthritis drug and agents for improving peripheral blood circulation.
    Type: Grant
    Filed: September 19, 1996
    Date of Patent: June 8, 1999
    Assignee: Sunkyong Industries, Ltd.
    Inventors: Wie-jong Kwak, Chang-kyun Han, Hwan-su Kim, Jae-suk An, Taek-soo Kim