Abstract: This invention relates to inhibitors of CXC receptor 4 (CXCR4)-G protein-coupled receptor (GPCR) heteromers (CXCR4-GPCR heteromers) associated with cancers, where CXCR4 forms a functional heteromer with other G protein-coupled receptors (GPCRx). More specifically, this invention relates to GPCRx that form heteromers with CXCR4, which upon co-stimulation with CXCR4 agonists and GPCRx agonists leads to enhanced signaling downstream of CXCR4. This invention also provides for the use of inhibitors of the interacting GPCR partner of the CXCR4-GPCRx heteromer or CXCR4-GPCRx heteromer-specific inhibitors including inhibitors of the formation of the CXCR4-GPCRx heteromer and CXCR4-GPCRx heteromer-specific antibodies, and in the diagnosis and/or therapy for cancer.

Abstract: This invention relates to inhibitors of CXC receptor 4 (CXCR4)-G protein-coupled receptor (GPCR) heteromers (CXCR4-GPCR heteromers) associated with cancers, where CXCR4 forms a functional heteromer with other G protein-coupled receptors (GPCRx). More specifically, this invention relates to ADRB2 that form heteromers with CXCR4, which upon co-stimulation with CXCR4 agonists and ADRB2 agonists leads to enhanced signaling downstream of CXCR4. This invention also provides for pharmaceutical compositions and kits comprising a CXCR4 inhibitor and an ADRB2 inhibitor, and methods for treating and using the same, and in the diagnosis and/or therapy for cancer.

Abstract: This invention relates to inhibitors of CXC receptor 4 (CXCR4)-G protein-coupled receptor (GPCR) heteromers (CXCR4-GPCR heteromers) associated with cancers, where CXCR4 forms a functional heteromer with other G protein-coupled receptors (GPCRx). More specifically, this invention relates to GPCRx that form heteromers with CXCR4, which upon co-stimulation with CXCR4 agonists and GPCRx agonists leads to enhanced signaling downstream of CXCR4. This invention also provides for the use of inhibitors of the interacting GPCR partner of the CXCR4-GPCRx heteromer or CXCR4-GPCRx heteromer-specific inhibitors including inhibitors of the formation of the CXCR4-GPCRx heteromer and CXCR4-GPCRx heteromer-specific antibodies, and in the diagnosis and/or therapy for cancer.

Abstract: This invention relates to inhibitors of CXC receptor 4 (CXCR4)-G protein-coupled receptor (GPCR) heteromers (CXCR4-GPCR heteromers) associated with cancers, where CXCR4 forms a functional heteromer with other G protein-coupled receptors (GPCRx). More specifically, this invention relates to GPCRx that form heteromers with CXCR4, which upon co-stimulation with CXCR4 agonists and GPCRx agonists leads to enhanced signaling downstream of CXCR4. This invention also provides for the use of inhibitors of the interacting GPCR partner of the CXCR4-GPCRx heteromer or CXCR4-GPCRx heteromer-specific inhibitors including inhibitors of the formation of the CXCR4-GPCRx heteromer and CXCR4-GPCRx heteromer-specific antibodies, and in the diagnosis and/or therapy for cancer.

Abstract: This invention relates to inhibitors of CXC receptor 4 (CXCR4)-G protein-coupled receptor (GPCR) heteromers (CXCR4-GPCR heteromers) associated with cancers, where CXCR4 forms a functional heteromer with other G protein-coupled receptors (GPCRx). More specifically, this invention relates to GPCRx that form heteromers with CXCR4, which upon co-stimulation with CXCR4 agonists and GPCRx agonists leads to enhanced signaling downstream of CXCR4. This invention also provides for the use of inhibitors of the interacting GPCR partner of the CXCR4-GPCRx heteromer or CXCR4-GPCRx heteromer-specific inhibitors including inhibitors of the formation of the CXCR4-GPCRx heteromer and CXCR4-GPCRx heteromer-specific antibodies, and in the diagnosis and/or therapy for cancer.

Abstract: This invention relates to inhibitors of CXC receptor 4 (CXCR4)-G protein-coupled receptor (GPCR) heteromers (CXCR4-GPCR heteromers) associated with cancers, where CXCR4 forms a functional heteromer with other G protein-coupled receptors (GPCRx). More specifically, this invention relates to GPCRx that form heteromers with CXCR4, which upon co-stimulation with CXCR4 agonists and GPCRx agonists leads to enhanced signaling downstream of CXCR4. This invention also provides for the use of inhibitors of the interacting GPCR partner of the CXCR4-GPCRx heteromer or CXCR4-GPCRx heteromer-specific inhibitors including inhibitors of the formation of the CXCR4-GPCRx heteromer and CXCR4-GPCRx heteromer-specific antibodies, and in the diagnosis and/or therapy for cancer.

Abstract: An electronic label system is provided. The electronic label operates in one of two operation modes between a real-time update mode in which merchandise information is updated in real time according to update setting information received from a management server and stored, and a delayed update mode in which merchandise information update is delayed. In the electronic label system, merchandise information may be updated in real time at a necessary point in time with a longer battery change period.

Abstract: The present invention provides a wireless device and method for reducing standby power. The method for reducing standby power of the wireless device includes the steps of: charging a charging battery with power supplied from an AC commercial power source in a normal mode of the wireless device, blocking the power of the AC commercial power source and converting an operation state of the wireless device so that the wireless device is in a standby mode when an operation-off signal used for turning off a predetermined device is transmitted from an outside. In this case, the wireless device receives the power with which the charging battery has been charged. In a standby mode, the wires device is periodically converted to be in a normal mode to transmit an operation state inquiry signal to the outside, so that it is possible to normally control the predetermined device.

Abstract: Disclosed herein is a power monitoring apparatus supplying power applied to a plug to an electrical device through a socket, the power monitoring apparatus including: a detecting unit sensing intensity of current applied to the electrical device to detect an operational state of the electrical device; a power supply unit supplying the power applied to the plug to each component; and a switching unit connected between a connection point between the plug and the socket and the power supply unit and applying the power to the power supply unit or blocking the power applied to the power supply unit according to the operational state of the electrical device.

Abstract: Provided are a power monitoring apparatus of standby power saving type, an electric load device, and a power monitoring method. The power monitoring apparatus of standby power saving type includes: a power metering module measuring a power consumption situation of an electric load device, transmitting a measured result to a communication module, and switching off when a standby mode of the electric load device is held for more than a preset time or the electric load device is off; the communication module being supplied with power upon the switching-on, transmitting a power consumption value received from the power metering module to exterior, being supplied with standby power upon the switching-off to wait for receiving a call signal, and switching on a switch upon reception of the call signal; and a charging module starting charging upon the switching-on, and supplying standby power to the communication module upon the switching-off.

Abstract: A parallel sequence spread spectrum type chaotic signal transmission device is disclosed to convert a serial data signal into a parallel data signal and transmit a chaotic signal according to the converted data signal. The parallel sequence spread spectrum type chaotic signal transmission device includes: a signal converting unit that converts serial data desired to be transmitted into parallel data having a pre-set unit; a chaotic signal generating unit that generates a pre-set chaotic signal; and an amplifying unit that amplifies the chaotic signal from the chaotic signal generating unit according to the data which has been converted by the signal converting unit.

Abstract: Disclosed herein is a method for operating an ESL system including a server and en electronic tag in which a time which elapses from the time when a power supply of the electronic tag is turned on is appropriated, execution reservation condition information is included in a signal transmitted from the server to the electronic tag, and the electronic tag operates in accordance with an execution reservation condition included in the signal received from the server.

Abstract: There is provided an electronic shelf label including an image display unit displaying a first image; a sensor unit detecting image switching signals; and a processor unit determining whether the image switching signals detected by the sensor unit are valid and switching the first image displayed on the image display unit to a second image when the image switching signals are valid, and a communication unit receiving a plurality of image data displayed on the image display unit. The processor unit determines that the image switching signals are valid when a detection duration time of the image switching signals is longer than a predetermined first threshold time. By this configuration, the electronic shelf label can switch a plurality of images and reduce the influence of disturbance to thereby prevent unnecessary image switching. Further, the electronic shelf label can provide product-related information for a manager or the like as well as for a purchaser.

Abstract: Disclosed herein are a power supply device and a lighting system having the same. The lighting system includes a power supply device including at least two converters that receive AC power and convert it into DC power and selectively outputting any one DC power thereof; and a plurality of LED lighting units each receiving the DC power from the power supply device and operating. The lighting system can stably supply power and facilitate maintenance thereof due to the use of the integrated power supply device.

Abstract: The present invention provides a wireless device and method for reducing standby power. The method for reducing standby power of the wireless device includes the steps of: charging a charging battery with power supplied from an AC commercial power source in a normal mode of the wireless device, blocking the power of the AC commercial power source and converting an operation state of the wireless device so that the wireless device is in a standby mode when an operation-off signal used for turning off a predetermined device is transmitted from an outside. In this case, the wireless device receives the power with which the charging battery has been charged. In a standby mode, the wires device is periodically converted to be in a normal mode to transmit an operation state inquiry signal to the outside, so that it is possible to normally control the predetermined device.

Abstract: Provided is a method for compensating performance degradation of a radio frequency integrated circuit (RFIC) using an EM simulation.

Abstract: There are provided a direct sampling type wireless receiver and a method using the same that reduce nonlinearity and DC offset by using a multi-port network and a carrier frequency direct conversion method with a low sampling rate of a direct sampling method in a wireless communication receiver.

Abstract: Provided is a device for generating a chaotic signal comprising a PN signal generator that is composed of a digital logic circuit and generates a digital pseudo random signal with a predetermined frequency; a voltage control that generates a clock signal with a predetermined frequency; a mixer that mixes the pseudo random signal and the clock signal so as to generate a chaotic signal to output; and a band-pass filter that filters the chaotic signal, output from the mixer, into a chaotic signal of a desired band and then outputs the filtered signal.

Abstract: There is provided a distance measuring apparatus having system flexibility by varying a distance measuring range and a distance measuring resolution according to an environment and circumstance. The apparatus includes a reference pulse generator and a delay pulse generator capable of controlling frequencies of a reference pulse and a delay pulse and duty ratios of the reference pulse and the delay pulse. The reference pulse generator and the delay pulse generator include a programmable clock generation unit generating a clock of a frequency determined by a frequency control signal and a duty ratio control unit controlling a duty ratio of the clock generated by the programmable clock generation unit.

Abstract: A parallel sequence spread spectrum type chaotic signal transmission device is disclosed to convert a serial data signal into a parallel data signal and transmit a chaotic signal according to the converted data signal. The parallel sequence spread spectrum type chaotic signal transmission device includes: a signal converting unit that converts serial data desired to be transmitted into parallel data having a pre-set unit; a chaotic signal generating unit that generates a pre-set chaotic signal; and an amplifying unit that amplifies the chaotic signal from the chaotic signal generating unit according to the data which has been converted by the signal converting unit.