Patents by Inventor Chang-Yi Lu

Chang-Yi Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250067742
    Abstract: A noninvasive liver cancer occurrence detecting method has steps of performing biomarker identification of a group of differentially methylated genes in a computing system; performing quantitative measurement of the methylation levels of a plurality of biomarkers selected from the group of differentially methylated genes with quantitative methylation-specific PCR (qMSP) in the computing system; performing calculation in the computing system to obtain M-score of the selected biomarkers according to the measured methylation levels of the selected biomarkers; and performing a risk level evaluation of liver cancer with the M-score in the computing system.
    Type: Application
    Filed: August 23, 2024
    Publication date: February 27, 2025
    Inventors: Chang-Yi LU, Pey-Jey PENG
  • Publication number: 20240304328
    Abstract: A method of detecting early recurrence of liver has steps of performing identification of a plurality of differentially methylated genes in a computing system; performing qualitative measurement of methylation levels of the methylated genes and performing quantitative measurement of the methylation levels of the methylated genes in the computing system; performing construction of a methylation prediction model of the methylated genes based on the measured methylation levels of the methylated genes in the computing system; and performing detection of early recurrence of liver cancer with the methylation prediction model in the computing system.
    Type: Application
    Filed: February 20, 2024
    Publication date: September 12, 2024
    Inventors: Chang-Yi LU, Pey-Jey PENG
  • Publication number: 20170183737
    Abstract: The disclosure provides a method for estimating a risk for a subject suffering from hepatocellular carcinoma, including: (a) determining methylation levels of APC gene, COX2 gene, RASSF1A gene and micro RNA-203 gene in a sample of a subject, respectively; (b) calculating a predicted score according to the methylation levels of the APC gene, COX2 gene, RASSF1A gene and micro RNA-203 gene; and (c) estimating a risk level for the subject suffering from hepatocellular carcinoma according to the predicted score.
    Type: Application
    Filed: December 30, 2015
    Publication date: June 29, 2017
    Applicant: Industrial Technology Research Institute
    Inventors: Chang-Yi LU, Chia-Jui YEN, Shih-Ya CHEN, Chia-Ju LIN, Yi-Chen LIU, Pu-Yeh KAN, Hui-Ling PENG, Wan-Chi CHANG, Chao-Yun TSAO
  • Patent number: 8846316
    Abstract: The disclosure relates to a method for determining incidence of liver cancer in a subject, including detecting methylation level or expression level of one microRNA miR-129-2 in a bio-sample from the subject. In the case that the methylation level of the microRNA in the bio-sample is higher or the expression level of the microRNA in the bio-sample is lower relative to that of the corresponding microRNA in a control sample, indicates that the subject is predisposed to or afflicted with liver cancer.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: September 30, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Chang-Yi Lu, Meng-Tsung Tien, Cheng-Tao Wu, Yih-Huei Uen, Kai-Yuan Lin
  • Publication number: 20130288239
    Abstract: The disclosure relates to a method for determining incidence of liver cancer in a subject, including detecting methylation level or expression level of one microRNA miR-129-2 in a bio-sample from the subject. In the case that the methylation level of the microRNA in the bio-sample is higher or the expression level of the microRNA in the bio-sample is lower relative to that of the corresponding microRNA in a control sample, indicates that the subject is predisposed to or afflicted with liver cancer.
    Type: Application
    Filed: November 26, 2012
    Publication date: October 31, 2013
    Applicant: Industrial Technology Research Institute
    Inventors: Chang-Yi LU, Meng-Tsung TIEN, Cheng-Tao WU, Yih-Huei UEN, Kai-Yuan LIN
  • Publication number: 20110236237
    Abstract: A fan includes an impeller, a motor, a circuit board, a fan frame and a connecting member. The motor is used to drive the impeller to rotate. The circuit board is electrically connected to the motor. The impeller and the motor are accommodated in the fan frame. The connecting member is disposed at one side of the fan frame. The circuit board is disposed between the connecting member and the fan frame. Also, a fan assembly including such two fans is also disclosed.
    Type: Application
    Filed: June 2, 2011
    Publication date: September 29, 2011
    Inventors: Yi-Fang CHOU, Hui-Chun Chang, Chang-Yi Lu, Li-Chen Lin
  • Patent number: 7985056
    Abstract: A fan includes an impeller, a motor, a circuit board, a fan frame and a connecting member. The motor is used to drive the impeller to rotate. The circuit board is electrically connected to the motor. The impeller and the motor are accommodated in the fan frame. The connecting member is disposed at one side of the fan frame. The circuit board is disposed between the connecting member and the fan frame. Also, a fan assembly including such two fans is also disclosed.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: July 26, 2011
    Assignee: Delta Electronics, Inc.
    Inventors: Yi-Fang Chou, Hui-Chun Chang, Chang-Yi Lu, Li-Chen Lin
  • Publication number: 20080279694
    Abstract: A fan includes an impeller, a motor, a circuit board, a fan frame and a connecting member. The motor is used to drive the impeller to rotate. The circuit board is electrically connected to the motor. The impeller and the motor are accommodated in the fan frame. The connecting member is disposed at one side of the fan frame. The circuit board is disposed between the connecting member and the fan frame. Also, a fan assembly including such two fans is also disclosed.
    Type: Application
    Filed: February 7, 2008
    Publication date: November 13, 2008
    Inventors: Yi-Fang CHOU, Hui-Chun Chang, Chang-Yi Lu, Li-Chen Lin