Abstract: A method includes forming a redistribution structure including metallization patterns; attaching a semiconductor device to a first side of the redistribution structure; encapsulating the semiconductor device with a first encapsulant; forming openings in the first encapsulant, the openings exposing a metallization pattern of the redistribution structure; forming a conductive material in the openings, comprising at least partially filling the openings with a conductive paste; after forming the conductive material, attaching integrated devices to a second side of the redistribution structure; encapsulating the integrated devices with a second encapsulant; and after encapsulating the integrated devices, forming a pre-solder material on the conductive material.

Abstract: The present disclosure is directed to peptide immunogen constructs targeting portions of Islet Amyloid Polypeptide (IAPP), compositions containing the constructs, antibodies elicited by the constructs, and methods for making and using the constructs and compositions thereof. The disclosed peptide immunogen constructs have more than about 30 amino acids and contain (a) a B cell epitope having about more than about 6 contiguous amino acid residues from the IAPP aggregation prone region of the full-length IAPP protein; (b) a heterologous Th epitope; and (c) an optional heterologous spacer. The disclosed IAPP peptide immunogen constructs stimulate the generation of highly specific antibodies directed IAPP for the prevention and/or treatment of disorders associated with aggregated IAPP.

Abstract: The disclosure generally relates to improving affinity interactions by the formation of an interconnected affinity agent network within a porous substrate via the use of metal complexes. More particularly, the disclosure generally relates to a binding support comprising a porous substrate as a component of a lateral flow assay device comprising at least one affinity agent associated with at least one metal coordination complex which forms an at least partially interconnected network with the porous substrate.

Abstract: A method includes forming a redistribution structure including metallization patterns; attaching a semiconductor device to a first side of the redistribution structure; encapsulating the semiconductor device with a first encapsulant; forming openings in the first encapsulant, the openings exposing a metallization pattern of the redistribution structure; forming a conductive material in the openings, comprising at least partially filling the openings with a conductive paste; after forming the conductive material, attaching integrated devices to a second side of the redistribution structure; encapsulating the integrated devices with a second encapsulant; and after encapsulating the integrated devices, forming a pre-solder material on the conductive material.

Abstract: A wireless communication device configured to operate with a first wireless communication protocol and a second wireless communication protocol and a method for performing coexistence control based on adaptive threshold adjustment in the wireless communication device are provided. The method may include: performing wireless communication operations with the first wireless communication protocol and the second wireless communication protocol concurrently; comparing a current throughput with a throughput threshold; in response to the current throughput being less than the throughput threshold, comparing a received signal strength indicator (RSSI), in communication using the second wireless communication protocol, with a signal strength threshold to generate at least one comparison result; and selectively sending a null frame according to the at least one comparison result, in order to temporarily avoid communication using the second wireless communication protocol.

Abstract: A method of detecting early recurrence of liver has steps of performing identification of a plurality of differentially methylated genes in a computing system; performing qualitative measurement of methylation levels of the methylated genes and performing quantitative measurement of the methylation levels of the methylated genes in the computing system; performing construction of a methylation prediction model of the methylated genes based on the measured methylation levels of the methylated genes in the computing system; and performing detection of early recurrence of liver cancer with the methylation prediction model in the computing system.

Abstract: A wireless communications device and a method for performing transmission and reception control of wireless communications device are provided. The method may include: utilizing a first communications control circuit to determine at least one indication regarding the first communications control circuit, for being sent to a second communications control circuit; utilizing the second communications control circuit to receive the at least one indication from the first communications control circuit, for indicating at least one behavior of the first communications control circuit; and utilizing the second communications control circuit to determine transmission power of the second communications control circuit at least according to whether multiple conditions (e.g.

Abstract: An annular airflow regulating apparatus includes a cup-shaped element and an adjustment element. The cup-shaped element has a bowl and a bottom, integrated to form a first chamber. The bottom has a tapered channel parallel to an axis and penetrating through the bottom. A ring-shaped groove is disposed between the tapered channel and the bottom. The ring-shaped groove has an annular plane perpendicular to the axis. The adjustment element, having a tapered portion and second holes, is movably disposed in the cup-shaped element. The tapered portion protrudes into the tapered channel A tapered annular gap is formed between the tapered portion and the tapered channel. When the adjustment element is moved with respect to the cup-shaped element, a width of the tapered annular gap is varied, and thereupon a flow rate and velocity of the process gas would be varied accordingly.

Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.

Abstract: An optical module for bi-directional monochromatic transmission is provided. The optical module includes a substrate, a common terminal, a circulator module, a multiplex-demultiplex (MDM) module, and an input-output terminal. The common terminal is adjacent to the substrate and connected to an optical fiber. The circulator module is on the substrate and in free space optical communication with the common terminal The MDM module is on the substrate and in free space optical communication with the circulator. The input-output terminal is on the substrate and in free space optical communication with the MDM module, the input-output terminal being configured to connect to an emitter and a receiver. The circulator is configured to spatially separate a first directional transmission to the MDM module from a second directional transmission from the MDM module.

Abstract: An optical inspection system includes: cameras, which capture images of partitioned areas of a substrate, respectively; inspection computers, which receive partial original images corresponding to the partitioned areas from the cameras, respectively, and transmit the partial original images through a many-to-one network; and a storage computer, which receives the partial original images, generates a full original image by merging the partial original images, and generates a full compressed image by extracting an effective area from the full original image.

Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.

Abstract: The present invention relates to a method of forming a cured conductive binder material, to a method of forming a curable binder formulation, to a curable binder formulation, to a cured conductive binder material and to an electrochemical cell. The approached described may be useful for the formation of electrodes and other electroactive materials.

Abstract: The present disclosure is directed to individual peptide immunogen constructs targeting portions of the Tau protein for the treatment and/or prevention of tauopathies. The present disclosure is also directed to compositions containing the peptide immunogen constructs, methods of making and using the peptide immunogen constructs, and antibodies produced by the peptide immunogen constructs.

Abstract: A fusion protein is disclosed. The fusion protein of the invention comprises an Fc fragment of an immunoglobulin G and a bioactive molecule, wherein the Fc is a single chain Fc. The amino acids in the hinge of the Fc is mutated, substituted, or deleted so that the hinge of Fc cannot form disulfide bonds. Methods for producing and using the fusion protein of the invention are also provided.

Abstract: An annular airflow regulating apparatus includes a cup-shaped element and an adjustment element. The cup-shaped element has a bowl and a bottom, integrated to form a first chamber. The bottom has a tapered channel parallel to an axis and penetrating through the bottom. A ring-shaped groove is disposed between the tapered channel and the bottom. The ring-shaped groove has an annular plane perpendicular to the axis. The adjustment element, having a tapered portion and second holes, is movably disposed in the cup-shaped element. The tapered portion protrudes into the tapered channel A tapered annular gap is formed between the tapered portion and the tapered channel. When the adjustment element is moved with respect to the cup-shaped element, a width of the tapered annular gap is varied, and thereupon a flow rate and velocity of the process gas would be varied accordingly.

Abstract: The present disclosure provides an optical device including a tray with a step structure, first filters, second filters, and an optical signal router. The step structure has a first portion and a second portion laterally connected to the first portion. The first portion has a first bottom surface and a first top surface. The second portion has a second bottom surface and a second top surface. The first bottom surface and the second bottom surface are substantially coplanar, and the first portion is thinner than the second portion. The first filters are mounted on the first top surface. The second filters are mounted on the second top surface. The optical signal router optically couples to the first filters and the second filters, and is configured to receive a light beam, transmissible to the tray, from one of the first filters or the second filters.

Abstract: The present invention relates to the treatment of herpes simplex virus (HSV) infection using an anti-HSV antibody. In particular, the anti-HSV antibody specifically binds to the glycoprotein D (gD) of herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2). The treatment of the present invention is effective against drug-resistant and/or recurrent HSV infection.

Abstract: This invention resides in using metal complex-activated particles to bind molecules, polymers and other particles to each other, so as to produce multifunctional conjugates having controlled ratios of two or more different molecules.

Abstract: An optical module for bi-directional monochromatic transmission is provided. The optical module includes a substrate, a common terminal, a circulator module, a multiplex-demultiplex (MDM) module, and an input-output terminal. The common terminal is adjacent to the substrate and connected to an optical fiber. The circulator module is on the substrate and in free space optical communication with the common terminal The MDM module is on the substrate and in free space optical communication with the circulator. The input-output terminal is on the substrate and in free space optical communication with the MDM module, the input-output terminal being configured to connect to an emitter and a receiver. The circulator is configured to spatially separate a first directional transmission to the MDM module from a second directional transmission from the MDM module.