Patents by Inventor Chang-yun Xiong

Chang-yun Xiong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11034736
    Abstract: An isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 1, 2, or 3, wherein the at least eight contiguous amino acids have anti-viral activity, as well as an isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 1, 2, or 3, wherein the at least eight contiguous amino acids have anti-viral activity, a vector comprising such an isolated and purified nucleic acid molecule, a host cell comprising the nucleic acid molecule, optionally in the form of a vector, a method of producing an antiviral polypeptide or conjugate thereof, the anti-viral polypeptide itself, a conjugate or fusion protein comprising the anti-viral polypeptide, and compositions comprising an effective amount of the anti-viral polypeptide or conjugate or fusion protein thereof. Further provided are methods of inhibiting prophylactically or therapeutically a viral infection of a host.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: June 15, 2021
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Barry R. O'Keefe, James B. McMahon, Koreen Ramessar, Chang-yun Xiong
  • Publication number: 20160333060
    Abstract: An isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 1, 2, or 3, wherein the at least eight contiguous amino acids have anti-viral activity, as well as an isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 1, 2, or 3, wherein the at least eight contiguous amino acids have anti-viral activity, a vector comprising such an isolated and purified nucleic acid molecule, a host cell comprising the nucleic acid molecule, optionally in the form of a vector, a method of producing an antiviral polypeptide or conjugate thereof, the anti-viral polypeptide itself, a conjugate or fusion protein comprising the anti-viral polypeptide, and compositions comprising an effective amount of the anti-viral polypeptide or conjugate or fusion protein thereof. Further provided are methods of inhibiting prophylactically or therapeutically a viral infection of a host.
    Type: Application
    Filed: January 9, 2015
    Publication date: November 17, 2016
    Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SER . . .
    Inventors: Barry R. O'Keefe, James B. McMahon, Koreen Ramessar, Chang-yun Xiong
  • Patent number: 8481255
    Abstract: A scytovirin domain 1 (SD1) polypeptide, a nucleic acid encoding the polypeptide, and related fusion proteins, conjugates, isolated cells, vectors, and antibodies, as well as a method of inhibiting a viral infection using the same.
    Type: Grant
    Filed: September 30, 2011
    Date of Patent: July 9, 2013
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Barry R. O'Keefe, Chang-yun Xiong, James B. McMahon, Andrew Byrd
  • Publication number: 20120053116
    Abstract: A scytovirin domain 1 (SD1) polypeptide, a nucleic acid encoding the polypeptide, and related fusion proteins, conjugates, isolated cells, vectors, and antibodies, as well as a method of inhibiting a viral infection using the same.
    Type: Application
    Filed: September 30, 2011
    Publication date: March 1, 2012
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health & Human Services
    Inventors: Barry R. O'Keefe, Chang-yun Xiong, James B. McMahon, Andrew Byrd
  • Patent number: 8067530
    Abstract: A scytovirin domain 1 (SD1) polypeptide, a nucleic acid encoding the polypeptide, and related fusion proteins, conjugates, isolated cells, vectors, and antibodies, as well as a method of inhibiting a viral infection using the same.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: November 29, 2011
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Barry R. O'Keefe, Chang-yun Xiong, James B. McMahon, Andrew Byrd
  • Publication number: 20080311125
    Abstract: A scytovirin domain 1 (SD1) polypeptide, a nucleic acid encoding the polypeptide, and related fusion proteins, conjugates, isolated cells, vectors, and antibodies, as well as a method of inhibiting a viral infection using the same.
    Type: Application
    Filed: May 24, 2006
    Publication date: December 18, 2008
    Applicant: Office of Technology Transfer
    Inventors: Barry R. O'Keefe, Chang-yun Xiong, James B. McMahon, Andrew Byrd