Patents by Inventor Changcan Shi

Changcan Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240261124
    Abstract: A PTMC-based intestinal anastomosis stent of a bioabsorbable flexible elastomer and a preparation method therefor. The intestinal anastomosis stent that uses PTMC as a base material is prepared by using an electrospinning method, and an appropriate range suitable for being implanted into the body is screened out according to a degradation rate and a mechanical property. The stent is loaded with TCS having a bactericidal effect, so that the stent has a tissue repair adjustment function, enabling a wound to heal more quickly in a severe multi-bacterial intestinal environment, and for adjusting postoperative tissue healing and functional repair. An in-vivo animal intestinal anastomosis experiment is carried out, thus verifying the practical effects and the feasibility of the method.
    Type: Application
    Filed: April 25, 2022
    Publication date: August 8, 2024
    Inventors: Changcan SHI, Xujian LI, Zhixiao JI, Luqi PAN, Xiao YANG
  • Patent number: 12048620
    Abstract: A flexible intestinal anastomosis stent which sucks secretions on an inner wall of an intestinal tract and at a suture site into a horn-shaped channel through a through-hole. The secretion is discharged to an inside of the stent body through a liquid-inlet hole after being squeezed by intestinal tract contents, thereby reducing a risk of infection at the suture site. A lower edge of the outlet end of the stent body has a concave polygonal structure, each reflex angle at a lower edge of the concave polygonal structure being formed with one inwardly folded wrinkle structure on a side wall of the stent body, and the wrinkle structure also able to accommodate the secretions. The lower edge is stressed and deformed by the intestinal tract contents to reduce a reflex angle, so that secretions in the wrinkle structure are discharged downwardly, such that risk of complications is reduced.
    Type: Grant
    Filed: April 25, 2022
    Date of Patent: July 30, 2024
    Assignee: WENZHOU INSTITUTE, UNIVERSITY OF CHINESE ACADEMY OF SCIENCES
    Inventors: Changcan Shi, Xujian Li, Zhixiao Ji, Luqi Pan, Xiao Yang
  • Publication number: 20240100228
    Abstract: A bioflexible elastomer intestinal anastomosis stent based on a PTMC-b-PEG-b-PTMC copolymer, and a preparation method. Biocompatible degradable polymer medical materials, i.e., PTMC and PEG, are selected, an electrostatic spinning method is used for preparation, the size of an anastomosis tube can be adjusted according to the size of a human lumen, and the anastomosis tube is designed to not only be suitable for an anastomat of the small intestines and large intestines, but also suitable for an anastomotic and pre-supported lumen anastomat of an esophagus, artery, vein, etc. The anastomosis tube prepared has a thin wall and excellent elasticity, and in order to facilitate suturing by a doctor during a clinical surgical operation, the anastomosis tube is innovatively and seamlessly sleeved outside a plant cellulose tube having high hardness.
    Type: Application
    Filed: April 25, 2022
    Publication date: March 28, 2024
    Inventors: Changcan SHI, Xujian LI, Luqi PAN, Zhixiao JI, Xiao YANG
  • Publication number: 20240099824
    Abstract: A flexible intestinal anastomosis stent which sucks secretions on an inner wall of an intestinal tract and at a suture site into a horn-shaped channel through a through-hole. The secretion is discharged to an inside of the stent body through a liquid-inlet hole after being squeezed by intestinal tract contents, thereby reducing a risk of infection at the suture site. A lower edge of the outlet end of the stent body has a concave polygonal structure, each reflex angle at a lower edge of the concave polygonal structure being formed with one inwardly folded wrinkle structure on a side wall of the stent body, and the wrinkle structure also able to accommodate the secretions. The lower edge is stressed and deformed by the intestinal tract contents to reduce a reflex angle, so that secretions in the wrinkle structure are discharged downwardly, such that risk of complications is reduced.
    Type: Application
    Filed: April 25, 2022
    Publication date: March 28, 2024
    Inventors: Changcan SHI, Xujian LI, Zhixiao JI, Luqi PAN, Xiao YANG
  • Patent number: 11707383
    Abstract: A method for manufacturing an inner drainage biomimetic stent for glaucoma. The inner drainage biomimetic stent for glaucoma comprises: a cylinder tube body with a hollow structure, and a plurality of straight tubes, provided inside the hollow structure of the tube body, for supporting a tube wall of the tube body. Proper placement of the inner drainage biomimetic stent for glaucoma can direct an aqueous humour to smoothly flow through an orifice expanded by the biomimetic stent, into Schlemm's canal.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: July 25, 2023
    Assignee: SuZhou Purevision Medical Technology Co., LTD.
    Inventors: Yuanbo Liang, Xingyi Li, Changcan Shi, Cheng Hu
  • Publication number: 20210128355
    Abstract: A method for manufacturing an inner drainage biomimetic stent for glaucoma. The inner drainage biomimetic stent for glaucoma comprises: a cylinder tube body with a hollow structure, and a plurality of straight tubes, provided inside the hollow structure of the tube body, for supporting a tube wall of the tube body. Proper placement of the inner drainage biomimetic stent for glaucoma can direct an aqueous humour to smoothly flow through an orifice expanded by the biomimetic stent, into Schlemm's canal.
    Type: Application
    Filed: March 31, 2017
    Publication date: May 6, 2021
    Inventors: Yuanbo LIANG, Xingyi LI, Changcan SHI, Cheng HU
  • Publication number: 20160339123
    Abstract: A polybutylacrylate-based nanocomposite photoacoustic imaging agent includes a biomedical material such as polybutylacrylate used as a main component and methylene blue or indocyanine green used as an entrapped component with particle diameters of 525.1 nm and 272.0 nm and electric potentials of ?4.52 mV and ?5.98 mV respectively. The preparation method of the polybutylacrylate-based nanocomposite photoacoustic imaging agent with the features of moderate eco-friendliness, low power consumption, and free of three industrial wastes, radiation, and noise pollution may be used for industrial production.
    Type: Application
    Filed: May 20, 2015
    Publication date: November 24, 2016
    Inventors: Zhe Liu, Yihong Li, Yuanhui Song, Changcan Shi, Jie Wang