Patents by Inventor Changfeng Wu

Changfeng Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12270067
    Abstract: The present disclosure provides nanoparticle transducers and methods of use thereof for the detection of analyte concentrations in a fluid. Nanoparticle transducers can comprise a nanoparticle, such as a Pdot, coupled to an enzyme that catalyzes a reaction with the analyte. The nanoparticle transducers further comprise chromophores that emit fluorescence that varies as a function of the concentration of one of the elements of the reaction. The nanoparticle transducer thus changes fluorescence as the analyte concentration changes, transforming analyte concentration values into fluorescence intensities. The measurement of these intensities provides a measurement of the analyte concentration. The nanoparticle transducers are biocompatible, allowing for use in vivo, for the monitoring of analyte blood concentrations such as blood glucose concentrations.
    Type: Grant
    Filed: November 23, 2022
    Date of Patent: April 8, 2025
    Assignees: University of Washington, Lamprogen, Inc.
    Inventors: Daniel T. Chiu, Jiangbo Yu, Changfeng Wu, Kai Sun
  • Patent number: 12272468
    Abstract: The present disclosure provides organic-inorganic hybrid polymer particles, which have desirable surface chemistry and optical properties that make them particularly suitable for biological and optical applications. The present disclosure also provides methods of making organic-inorganic hybrid polymer particles. The present disclosure also provides methods of using the organic-inorganic hybrid polymer particles for biological and optical applications.
    Type: Grant
    Filed: October 11, 2023
    Date of Patent: April 8, 2025
    Assignee: University of Washington
    Inventors: Daniel T. Chiu, Jiangbo Yu, Yu Rong, Changfeng Wu
  • Patent number: 12216124
    Abstract: The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized with a pre-determined number of functional groups. In certain embodiments, the stable chromophoric nanoparticles provided herein are modified with a low density of functional groups. In yet other embodiments, the chromophoric nanoparticles provided herein are conjugated to one or more molecules. Also provided herein are methods for making rationally functionalized chromophoric nanoparticles.
    Type: Grant
    Filed: November 23, 2022
    Date of Patent: February 4, 2025
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Daniel T. Chiu, Changfeng Wu, Xuanjun Zhang, Jiangbo Yu, Fangmao Ye
  • Publication number: 20250035636
    Abstract: The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized with a pre-determined number of functional groups. In certain embodiments, the stable chromophoric nanoparticles provided herein are modified with a low density of functional groups. In yet other embodiments, the chromophoric nanoparticles provided herein are conjugated to one or more molecules. Also provided herein are methods for making rationally functionalized chromophoric nanoparticles.
    Type: Application
    Filed: October 10, 2024
    Publication date: January 30, 2025
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Daniel T. Chiu, Changfeng Wu, Xuanjun Zhang, Jiangbo Yu, Fangmao Ye
  • Publication number: 20250007041
    Abstract: A heat-dissipating member, an energy-storage apparatus, and an electricity-consumption device are disclosed. The heat-dissipating member includes a first heat-dissipating portion and at least one second heat-dissipating portion. The first heat-dissipating portion is connected to each of the at least one second heat-dissipating portion to form a transition section. A liquid inlet channel and a liquid outlet channel of the heat-dissipating member both are positioned inside the first heat-dissipating portion and the at least one second heat-dissipating portion and pass through the transition section. Two harmonica-shaped tubes are disposed inside the transition section. Each of the two harmonica-shaped tubes defines a flow channel cavity. One flow channel cavity is in communication with the liquid inlet channel, and the other one flow channel cavity is in communication with the liquid outlet channel.
    Type: Application
    Filed: May 15, 2024
    Publication date: January 2, 2025
    Applicant: Xiamen Hithium Energy Storage Technology Co., Ltd.
    Inventors: Deliang ZHONG, Changfeng WU, Weipeng HUANG
  • Publication number: 20240254288
    Abstract: Polymers, monomers, chromophoric polymer dots and related methods are provided. Highly fluorescent chromophoric polymer dots with narrow-band emissions are provided. Methods for synthesizing the chromophoric polymers, preparation methods for forming the chromophoric polymer dots, and biological applications using the unique properties of narrow-band emissions are also provided.
    Type: Application
    Filed: May 15, 2023
    Publication date: August 1, 2024
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Daniel T. Chiu, Changfeng Wu, Yu Rong, Yong Zhang, Yi-Che Wu, Yang-Hsiang Chan, Xuanjun Zhang, Jiangbo Yu, Wei Sun
  • Publication number: 20240120574
    Abstract: The present disclosure provides a liquid cooling plate and battery pack. The liquid cooling plate is formed with a receiving space. The liquid cooling plate includes a first cooling plate and a second cooling plate. The second cooling plate is stacked on a side of the first cooling plate facing the receiving space and is connected to the first cooling plate in a sealed manner. A cooling flow passage surrounding the receiving space is formed between the second cooling plate and the first cooling plate.
    Type: Application
    Filed: December 22, 2023
    Publication date: April 11, 2024
    Applicant: XIAMEN HITHIUM ENERGY STORAGE TECHNOLOGY CO., LTD.
    Inventors: Weipeng HUANG, Changfeng WU, Xiaoxiao JING
  • Publication number: 20240069032
    Abstract: The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.
    Type: Application
    Filed: October 23, 2023
    Publication date: February 29, 2024
    Inventors: Daniel T. Chiu, Changfeng Wu, Jason McNeil, Jiangbo Yu
  • Publication number: 20240063466
    Abstract: The present disclosure provides a liquid cooling plate and a battery pack. The liquid cooling plate includes a first cooling plate, a second cooling plate and at least one reinforcement member. The first cooling plate includes a first bent part. The second cooling plate is arranged side by side with the first cooling plate and is connected with the first cooling plate in a sealed manner. A cooling flow passage is formed between the second cooling plate and the first cooling plate. The second cooling plate includes a second bent part, and the second bent part corresponds to the first bent part. The at least one reinforcement member is disposed in the cooling flow passage between the first bent part and the second bent part.
    Type: Application
    Filed: November 3, 2023
    Publication date: February 22, 2024
    Applicant: XIAMEN HITHIUM ENERGY STORAGE TECHNOLOGY CO., LTD.
    Inventors: Weipeng HUANG, Changfeng WU, Xiaoxiao JING
  • Publication number: 20240047098
    Abstract: The present disclosure provides organic-inorganic hybrid polymer particles, which have desirable surface chemistry and optical properties that make them particularly suitable for biological and optical applications. The present disclosure also provides methods of making organic-inorganic hybrid polymer particles. The present disclosure also provides methods of using the organic-inorganic hybrid polymer particles for biological and optical applications.
    Type: Application
    Filed: October 11, 2023
    Publication date: February 8, 2024
    Applicant: University of Washington
    Inventors: Daniel T. CHIU, Jiangbo YU, Yu RONG, Changfeng WU
  • Publication number: 20230408526
    Abstract: The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized with a pre-determined number of functional groups. In certain embodiments, the stable chromophoric nanoparticles provided herein are modified with a low density of functional groups. In yet other embodiments, the chromophoric nanoparticles provided herein are conjugated to one or more molecules. Also provided herein are methods for making rationally functionalized chromophoric nanoparticles.
    Type: Application
    Filed: November 23, 2022
    Publication date: December 21, 2023
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Daniel T. Chiu, Changfeng Wu, Xuanjun Zhang, Jiangbo Yu, Fangmao Ye
  • Patent number: 11835526
    Abstract: The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.
    Type: Grant
    Filed: February 15, 2022
    Date of Patent: December 5, 2023
    Assignees: University of Washington, Clemson University Research Foundation
    Inventors: Daniel T. Chiu, Changfeng Wu, Jason McNeill, Jiangbo Yu
  • Patent number: 11823809
    Abstract: The present disclosure provides organic-inorganic hybrid polymer particles, which have desirable surface chemistry and optical properties that make them particularly suitable for biological and optical applications. The present disclosure also provides methods of making organic-inorganic hybrid polymer particles. The present disclosure also provides methods of using the organic-inorganic hybrid polymer particles for biological and optical applications.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: November 21, 2023
    Assignee: University of Washington
    Inventors: Daniel T. Chiu, Jiangbo Yu, Yu Rong, Changfeng Wu
  • Patent number: 11774513
    Abstract: A method for predicting a life includes the following. Obtain multiple cycle numbers of a battery and multiple capacity data corresponding to the cycle numbers. Obtain multiple sets of first fitting data by fitting the cycle numbers and the capacity data with a bi-exponential empirical model. Obtain multiple sets of second fitting data by fitting the cycle numbers and the capacity data with a box-cox transformation method. Determine a first capacity error according to the multiple sets of first fitting data and the multiple capacity data. Determine a second capacity error according to the multiple sets of second fitting data and the capacity data. Generate a battery-life prediction model according to the first capacity error, the second capacity error, the multiple sets of first fitting data, and the multiple sets of second fitting data. Determine an RUL of the battery according to a predetermined battery-capacity-value and the battery-life prediction model.
    Type: Grant
    Filed: March 16, 2023
    Date of Patent: October 3, 2023
    Assignees: Shenzhen Hairun New Energy Technology Co., Ltd., Xiamen Hithium Energy Storage Technology Co., Ltd.
    Inventors: Xiang Cai, Changfeng Wu
  • Patent number: 11697713
    Abstract: Polymers, monomers, chromophoric polymer dots and related methods are provided. Highly fluorescent chromophoric polymer dots with narrow-band emissions are provided. Methods for synthesizing the chromophoric polymers, preparation methods for forming the chromophoric polymer dots, and biological applications using the unique properties of narrow-band emissions are also provided.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: July 11, 2023
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Daniel T. Chiu, Changfeng Wu, Yu Rong, Yong Zhang, Yi-Che Wu, Yang-Hsiang Chan, Xuanjun Zhang, Jiangbo Yu, Wei Sun
  • Patent number: 11674964
    Abstract: The present disclosure provides encoded chromophoric polymer particles that are capable of, for example, optical and/or biomolecular encoding of analytes. The present disclosure also provides suspensions comprising a plurality of encoded chromophoric polymer particles. The present disclosure also provides methods of using the encoded chromophoric polymer particles and systems for performing multiplex analysis with encoded chromophoric polymer particles.
    Type: Grant
    Filed: November 30, 2021
    Date of Patent: June 13, 2023
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Daniel T. Chiu, Changfeng Wu, Jiangbo Yu
  • Publication number: 20230077385
    Abstract: The present disclosure provides nanoparticle transducers and methods of use thereof for the detection of analyte concentrations in a fluid. Nanoparticle transducers can comprise a nanoparticle, such as a Pdot, coupled to an enzyme that catalyzes a reaction with the analyte. The nanoparticle transducers further comprise chromophores that emit fluorescence that varies as a function of the concentration of one of the elements of the reaction. The nanoparticle transducer thus changes fluorescence as the analyte concentration changes, transforming analyte concentration values into fluorescence intensities. The measurement of these intensities provides a measurement of the analyte concentration. The nanoparticle transducers are biocompatible, allowing for use in vivo, for the monitoring of analyte blood concentrations such as blood glucose concentrations.
    Type: Application
    Filed: November 23, 2022
    Publication date: March 16, 2023
    Applicants: University of Washington, LAMPROGEN, INC.
    Inventors: Daniel T. Chiu, Jiangbo Yu, Changfeng Wu, Kai Sun
  • Patent number: 11585818
    Abstract: The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized with a pre-determined number of functional groups. In certain embodiments, the stable chromophoric nanoparticles provided herein are modified with a low density of functional groups. In yet other embodiments, the chromophoric nanoparticles provided herein are conjugated to one or more molecules. Also provided herein are methods for making rationally functionalized chromophoric nanoparticles.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: February 21, 2023
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Daniel T. Chiu, Changfeng Wu, Xuanjun Zhang, Jiangbo Yu, Fangmao Ye
  • Patent number: 11542539
    Abstract: The present disclosure provides nanoparticle transducers and methods of use thereof for the detection of analyte concentrations in a fluid. Nanoparticle transducers can comprise a nanoparticle, such as a Pdot, coupled to an enzyme that catalyzes a reaction with the analyte. The nanoparticle transducers further comprise chromophores that emit fluorescence that varies as a function of the concentration of one of the elements of the reaction. The nanoparticle transducer thus changes fluorescence as the analyte concentration changes, transforming analyte concentration values into fluorescence intensities. The measurement of these intensities provides a measurement of the analyte concentration. The nanoparticle transducers are biocompatible, allowing for use in vivo, for the monitoring of analyte blood concentrations such as blood glucose concentrations.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: January 3, 2023
    Assignees: UNIVERSITY OF WASHINGTON, LAMPROGEN, INC.
    Inventors: Daniel T. Chiu, Jiangbo Yu, Changfeng Wu, Kai Sun
  • Publication number: 20220252607
    Abstract: The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.
    Type: Application
    Filed: February 15, 2022
    Publication date: August 11, 2022
    Inventors: Daniel T. Chiu, Changfeng Wu, Jason McNeill, Jiangbo Yu