Patents by Inventor Changhai Tian

Changhai Tian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and Compositions for Selective Generation of Dopaminergic Precursors
    Publication number: 20220213502
    Abstract: The present invention provides in general methods for transdifferentiation of a somatic cell, e.g., a fibroblast, to a dopaminergic precursor. Specifically, the present invention relates to methods for making iDP cells, and methods for using them in, e.g., treating neurodegenerative diseases such as Parkinson's disease.
    Type: Application
    Filed: January 18, 2022
    Publication date: July 7, 2022
    Applicants: Tongji University, Board of Regents of the University of Nebraska
    Inventors: Jialin Zheng, Changhai Tian
  • Methods and compositions for selective generation of dopaminergic precursors
    Patent number: 11261461
    Abstract: Provided are methods and compositions for transdifferentiation of a somatic cell, e.g., a fibroblast to a dopaminergic precursor, Specifically, provided are induced dopaminergic (iDP) cells, or master transcription factors (TFs) therefore, methods for making iDP cells, and methods and compositions for using them in, e.g., treating neurodegenerative diseases such as Parkinson's disease.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: March 1, 2022
    Assignees: Tongji University, Board of Regents of the University of Nebraska
    Inventors: Jialin Zheng, Changhai Tian
  • METHODS AND COMPOSITIONS FOR SELECTIVE GENERATION OF DOPAMINERGIC PRECURSORS
    Publication number: 20170268021
    Abstract: Provided are methods and compositions for transdifferentiation of a somatic cell, e.g., a fibroblast to a dopaminergic precursor, Specifically, provided are induced dopaminergic (iDP) cells, or master transcription factors (TFs) therefore, methods for making iDP cells, and methods and compositions for using them in, e.g., treating neurodegenerative diseases such as Parkinson's disease.
    Type: Application
    Filed: August 19, 2015
    Publication date: September 21, 2017
    Inventors: Jialin Zheng, Changhai Tian