Patents by Inventor Changhui Guan

Changhui Guan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Construction of a quadruple enterotoxin-deficient mutant of
    Patent number: 11375720
    Abstract: Some HBL and NHE enterotoxins are known to cause food-borne diseases in humans. Enterotoxin-deficient mutants of member strains of the Bacillus cereus group that do not produce HBL, HBLa1, HBLa2, or NHE enterotoxins are disclosed. Enterotoxin-deficient mutants are suitable for use as biocontrol agents. Methods for making the mutants and for using the mutants are described.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: July 5, 2022
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Jo Emily Handelsman, Amy Klimowicz, Changhui Guan
  • CONSTRUCTION OF A QUADRUPLE ENTEROTOXIN-DEFICIENT MUTANT OF BACILLUS THURINGIENSIS
    Publication number: 20180282739
    Abstract: Some HBL and NHE enterotoxins are known to cause food-borne diseases in humans. Enterotoxin-deficient mutants of member strains of the Bacillus cereus group that do not produce HBL, HBLa1, HBLa2, or NHE enterotoxins are disclosed. Enterotoxin-deficient mutants are suitable for use as biocontrol agents. Methods for making the mutants and for using the mutants are described.
    Type: Application
    Filed: June 11, 2018
    Publication date: October 4, 2018
    Inventors: Jo Emily Handelsman, Amy Klimowicz, Changhui Guan
  • Construction of a quadruple enterotoxin-deficient mutant of bacillus thuringiensis
    Patent number: 10017771
    Abstract: Some HBL and NHE enterotoxins are known to cause food-borne diseases in humans. Enterotoxin-deficient mutants of member strains of the Bacillus cereus group that do not produce HBL, HBLa1, HBLa2, or NHE enterotoxins are disclosed. Enterotoxin-deficient mutants are suitable for use as biocontrol agents. Methods for making the mutants and for using the mutants are described.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: July 10, 2018
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jo Emily Handelsman, Amy Klimowicz, Changhui Guan
  • CONSTRUCTION OF A QUADRUPLE ENTEROTOXIN-DEFICIENT MUTANT OF BACILLUS THURINGIENSIS
    Publication number: 20140341854
    Abstract: Some HBL and NHE enterotoxins are known to cause food-borne diseases in humans. Enterotoxin-deficient mutants of member strains of the Bacillus cereus group that do not produce HBL, HBLa1, HBLa2, or NHE enterotoxins are disclosed. Enterotoxin-deficient mutants are suitable for use as biocontrol agents. Methods for making the mutants and for using the mutants are described.
    Type: Application
    Filed: July 3, 2014
    Publication date: November 20, 2014
    Inventors: Jo Emily Handelsman, Amy Klimowicz, Changhui Guan
  • Construction of a quadruple enterotoxin-deficient mutant of
    Patent number: 8802420
    Abstract: Some HBL and NHE enterotoxins are known to cause food-borne diseases in humans. Enterotoxin-deficient mutants of member strains of the Bacillus cereus group that do not produce HBL, HBLa1, HBLa2, or NHE enterotoxins are disclosed. Enterotoxin-deficient mutants are suitable for use as biocontrol agents. Methods for making the mutants and for using the mutants are described.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: August 12, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jo Emily Handelsman, Amy Klimowicz, Changhui Guan
  • CONSTRUCTION OF A QUADRUPLE ENTEROTOXIN-DEFICIENT MUTANT OF BACILLUS THURINGIENSIS
    Publication number: 20120164105
    Abstract: Some HBL and NHE enterotoxins are known to cause food-borne diseases in humans. Enterotoxin-deficient mutants of member strains of the Bacillus cereus group that do not produce HBL, HBLa1, HBLa2, or NHE enterotoxins are disclosed. Enterotoxin-deficient mutants are suitable for use as biocontrol agents. Methods for making the mutants and for using the mutants are described.
    Type: Application
    Filed: June 7, 2011
    Publication date: June 28, 2012
    Inventors: Jo Emily Handelsman, Amy Klimowicz, Changhui Guan