Abstract: A method for building a coke own includes steps of building an oven body building three-dimensional control network, and building a coke side or machine side refractory brick receiving platform; based on the three-dimensional control network and the refractory brick receiving platform, marking out a laying position of each layer of refractory bricks layer by layer, arranging the refractory bricks required by laying of each layer by layer, laying the refractory bricks layer by layer according to the marking and the arrangement, jointing the laid refractory bricks layer by layer, cleaning the jointed refractory bricks layer by layer, and checking and accepting the cleaned refractory bricks layer by layer. In this method, quality control is carried out on coke oven body masonry on the whole through six dimensions.

Abstract: The present invention relates to a WEE1 inhibitor, and the preparation and use thereof. The WEE1 inhibitor of the present invention is a compound of Formula I or a compound of Formula II, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof. The present invention also provides use of the WEE1 inhibitor in the manufacture of a medicament for the treatment of a disease associated with WEE1 activity. The WEE1 inhibitor provided by the present invention can effectively treat the disease associated with WEE1 activity.