Patents by Inventor Changkun YANG

Changkun YANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240374647
    Abstract: Provided is an application of a sphere substance in the preparation of an intravenous injection, relating to the technical field of biomedicine. Intravenous injection of the sphere substance formed by MSC spheres or biomaterials is used as a new in-vivo delivery solution. Compared with the intravenous injection of discrete MSCs, the intravenous injection of the MSC spheres reduces the retention of the MSCs in lungs, and prolongs the-retention time and activity of the MSCs in blood and peripheral tissues, such that therapeutic effects for autoimmune diseases, inflammatory diseases, and tissues and organ injuries can be improved. In addition, the intravenous injection of biomaterial spheres is safe, can carry drugs, biologically active molecules or detection molecules, is applied to diagnosis and treatment of an animal disease model or a patient, is more effective and more durable than monomer molecules, and can also carry a variety of molecules to generate a synergistic effect.
    Type: Application
    Filed: April 21, 2022
    Publication date: November 14, 2024
    Inventors: Ren-He XU, Wei SI, Yaping YAN, Changkun YANG, Enqin LI
  • Patent number: 10731721
    Abstract: An elastic adjustable brake pad for use in a train, comprising a brake pad frame (1) provided with a fourth through hole (18), a brake block assembly, and a spiral compression spring (6); the brake block assembly comprises a brake block (16), a rivet (4), a Belleville spring (5), and a rivet sleeve (3), the brake block (16) comprising a friction block (10) and a static sheet steel back (7) fixedly mounted together, the rivet (4) passing through the brake block (16) and being sleeved in turn by the Belleville spring (5) and the rivet sleeve (3); the fourth through hole (18) is a stepped counterbore, and the rivet (4) in the brake block (16) penetrates the fourth through hole (18) and extends outward therefrom, the spiral compression spring (6) being sleeved over the outside of the rivet sleeve (3), and the outer side of one end of the rivet sleeve (3) being provided with a clamping groove clamped to an elastic retainer ring (2), one end of the spiral compression spring (6) abutting a step on which a secondary
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: August 4, 2020
    Assignee: BEIJING BEI MO GAO KE FRICTION MATERIAL CO. LTD
    Inventors: Jianfeng Chen, Changkun Yang, Xiang Zhao, Kai Xiao, Dan Zheng, Guangyu Li, Hua Feng, Xiaohua Liu, Yan Wang, Zhiwei Liu, Longjie Han, Xueqiang Li, Zhen Xiao, Hongbo Yang
  • Publication number: 20180266508
    Abstract: An elastic adjustable brake pad for use in a train, comprising a brake pad frame (1) provided with a fourth through hole (18), a brake block assembly, and a spiral compression spring (6); the brake block assembly comprises a brake block (16), a rivet (4), a Belleville spring (5), and a rivet sleeve (3), the brake block (16) comprising a friction block (10) and a static sheet steel back (7) fixedly mounted together, the rivet (4) passing through the brake block (16) and being sleeved in turn by the Belleville spring (5) and the rivet sleeve (3); the fourth through hole (18) is a stepped counterbore, and the rivet (4) in the brake block (16) penetrates the fourth through hole (18) and extends outward therefrom, the spiral compression spring (6) being sleeved over the outside of the rivet sleeve (3), and the outer side of one end of the rivet sleeve (3) being provided with a clamping groove clamped to an elastic retainer ring (2), one end of the spiral compression spring (6) abutting a step on which a secondary
    Type: Application
    Filed: April 20, 2017
    Publication date: September 20, 2018
    Inventors: Jianfeng CHEN, Changkun YANG, Xiang ZHAO, Kai XIAO, Dan ZHENG, Guangyu LI, Hua FENG, Xiaohua LIU, Yan WANG, Zhiwei LIU, Longjie HAN, Xueqiang LI, Zhen XIAO, Hongbo YANG