Abstract: Provided is an anti-Henipavirus monoclonal antibody having broad spectrum neutralization activity, wherein the antibody comprises a macaque variable region and a human constant region. The antibody of the present invention has good binding activity to both Nipah virus glycoprotein G and Hendra virus glycoprotein G, can effectively neutralize Nipahpseudovirus and Hendra pseudovirus, and can be used for preparing drugs for treating Henipavirus diseases.

Abstract: Disclosed is a monoclonal antibody 2G1 against an Ebola glycoprotein GP2 subunit. The monoclonal antibody has binding activity to EBOV GP, BDBV GP, SUDV GP, and RESTV GP, and can play a neutralizing role.

Abstract: Disclosed is a monoclonal antibody against the Rift Valley fever virus. The antibody is screened and obtained by means of flow cytometric sorting and single-cell PCR technology, and has a unique CDR region. Further disclosed is the use of the antibody in the preparation of a drug for treating Rift Valley fever. The monoclonal antibody against the Rift Valley fever virus has high efficiency and specific activity against the Rift Valley fever virus; and also has the characteristics of high expression, high degree of humanization and good stability, and is suitable for industrial production.

Abstract: Provided is an anti-Henipavirus monoclonal antibody having broad spectrum neutralization activity, wherein the antibody comprises a macaque variable region and a human constant region. The antibody of the present invention has good binding activity to both Nipah virus glycoprotein G and Hendra virus glycoprotein G, can effectively neutralize Nipahpseudovirus and Hendra pseudovirus, and can be used for preparing drugs for treating Henipavirus diseases.

Abstract: Disclosed is a monoclonal antibody 2G1 against an Ebola glycoprotein GP2 subunit. The monoclonal antibody has binding activity to EBOV GP, BDBV GP, SUDV GP, and RESTV GP, and can play a neutralizing role.

Abstract: Disclosed in the present invention is an anti-Nipah virus monoclonal antibody having neutralization activity. The antibody consists of a monkey-derived variable region and a human constant region, and both light and heavy chains of the monkey-derived variable region have unique CDR regions. The antibody provided by the present invention has an excellent antigen binding capability, and has good binding activity with Bangladesh Nipah virus and Malaysia Nipah virus glycoprotein G. The antibody can effectively neutralize the Nipahpseudovirus. Moreover, the neutralization activity of the antibody is enhanced as the concentration of the antibody increases, and nearly 100% neutralization of the Nipahpseudovirus can be achieved at a concentration of 1 ?g/mL. Also disclosed in the present invention is an application of the monoclonal antibody against the Nipah virus glycoprotein G in preparation of a Nipah virus treatment drug.

Abstract: A spectrally-resolved Raman water lidar, including: a transmitter unit, a receiver unit, and a data acquisition and control unit. The transmitter unit includes a seeder, a solid Neodymium-doped Yttrium Aluminum Garnet (Nd:YAG) laser, a beam expander, and a first reflecting mirror to emit a 354.8-nm laser beam. The receiver unit includes a telescope, an iris, a collimator, a second reflecting mirror, a first bandpass filter, a beam splitter, a narrow-band interference filter, a third lens, a first detector, a second bandpass filter, a coupler and a home-made dual-grating polychromator to enable simultaneous profiling of backscattered Raman spectrum signals from water vapor, water droplets and ice crystals as well as aerosol fluorescence in the atmosphere. The data acquisition and control unit includes a computer to store the acquired data and guarantee an automatic operation of the lidar system through a time-sequence circuit.

Abstract: A single-line-extracted pure rotational Raman lidar system, including: a transmitter unit configured to emit extremely narrow-band laser light that is guided into atmosphere zenithward; a receiver unit configured to collect backscattered signals from the atmosphere; and a data acquisition and control unit configured to deliver data and guarantee automatic operation of the lidar system orderly. The transmitter unit employs a powerful injection-seeded Nd: YAG laser to emit 532.23 nm laser beam with a pulse energy of approximately 800 mJ, a repetition rate of 30 Hz and linewidth of <0.006 cm?1. The lidar system has an optical bandwidth of approximately 30 pm for the two Raman channels and an optical bandwidth of 0.3 nm for an elastic channel, as well as a field of view of approximately 0.4 mrad. The two Raman channels extract the N2 anti-Stokes pure rotational Raman line signals with J=6 and 16, respectively.

Abstract: Provided are a platelet-derived growth factor B derivative, the encoding nucleic acid molecule thereof, and a vector and host cell having the nucleic acid molecule. Also provided are a preparation method for the mutant, and the use of the mutant in preparing medications for promoting cell division, cell proliferation, wound healing, skin regeneration, bone and tooth defect regeneration, and joint repair.

Abstract: A spectrally-resolved Raman water lidar, including: a transmitter unit, a receiver unit, and a data acquisition and control unit. The transmitter unit includes a seeder, a solid Neodymium-doped Yttrium Aluminum Garnet (Nd: YAG) laser, a beam expander, and a first reflecting mirror to emit a 354.8-nm laser beam. The receiver unit includes a telescope, an iris, a collimator, a second reflecting mirror, a first bandpass filter, a beam splitter, a narrow-band interference filter, a third lens, a first detector, a second bandpass filter, a coupler and a home-made dual-grating polychromator to enable simultaneous profiling of backscattered Raman spectrum signals from water vapor, water droplets and ice crystals as well as aerosol fluorescence in the atmosphere. The data acquisition and control unit includes a computer to store the acquired data and guarantee an automatic operation of the lidar system through a time-sequence circuit.

Abstract: A single-line-extracted pure rotational Raman lidar system, including: a transmitter unit configured to emit extremely narrow-band laser light that is guided into atmosphere zenithward; a receiver unit configured to collect backscattered signals from the atmosphere; and a data acquisition and control unit configured to deliver data and guarantee automatic operation of the lidar system orderly. The transmitter unit employs a powerful injection-seeded Nd: YAG laser to emit 532.23 nm laser beam with a pulse energy of approximately 800 mJ, a repetition rate of 30 Hz and linewidth of <0.006 cm?1. The lidar system has an optical bandwidth of approximately 30 pm for the two Raman channels and an optical bandwidth of 0.3 nm for an elastic channel, as well as a field of view of approximately 0.4 mrad. The two Raman channels extract the N2 anti-Stokes pure rotational Raman line signals with J=6 and 16, respectively.

Abstract: Provided are a platelet-derived growth factor B derivative, the encoding nucleic acid molecule thereof, and a vector and host cell having the nucleic acid molecule. Also provided are a preparation method for the mutant, and the use of the mutant in preparing medications for promoting cell division, cell proliferation, wound healing, skin regeneration, bone and tooth defect regeneration, and joint repair.