Patents by Inventor Changqing Lin
Changqing Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240087628Abstract: A multi-resistance-state spintronic device, including: a top electrode and a bottom electrode respectively connected to a read-write circuit; and a magnetic tunnel junction between two electrodes. The magnetic tunnel junction includes from top to bottom: a ferromagnetic reference layer, a barrier tunneling layer, a ferromagnetic free layer, and a spin-orbit coupling layer. Nucleation centers are provided at two ends of the ferromagnetic free layer to generate a magnetic domain wall; the spin-orbit coupling layer is connected to the bottom electrode, and when a write pulse is applied, an electron spin current is generated and drives the magnetic domain wall through a spin-orbit torque to move; a plurality of local magnetic domain wall pinning centers are provided at an interface between the spin-orbit coupling layer and the ferromagnetic free layer to enhance a strength of a DM interaction constant between interfaces.Type: ApplicationFiled: December 30, 2020Publication date: March 14, 2024Inventors: Guozhong XING, Huai LIN, Feng ZHANG, Di WANG, Long LIU, Changqing XIE, Ling LI, Ming LIU
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Publication number: 20240071451Abstract: The three-state spintronic device includes: a bottom electrode, a magnetic tunnel junction and a top electrode from bottom to top. The magnetic tunnel junction includes: a spin-orbit coupling layer, a ferromagnetic free layer, a barrier tunneling layer, a ferromagnetic reference layer, three local magnetic domain wall pinning centers and domain wall nucleation centers. An antisymmetric exchange interaction is modulated, and the magnetic domain wall pinning centers are embedded in an interface between a heavy metal and the ferromagnetic free layer. The magnetic domain wall nucleation centers are at two ends of the ferromagnetic free layer. A current pulse flows through the spin-orbit coupling layer to generate a spin current and the spin current is injected into the ferromagnetic free layer. Under a control of all-electrical controlled, an effective field of a spin-orbit torque drives domain wall to move and displace.Type: ApplicationFiled: January 21, 2021Publication date: February 29, 2024Inventors: Huai LIN, Guozhong XING, Zuheng WU, Long LIU, Di WANG, Cheng LU, Peiwen ZHANG, Changqing XIE, Ling LI, Ming LIU
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Publication number: 20230021840Abstract: Embodiments of the present invention relate to use of a GP73 inhibitor in preparation of a drug for treating diabetes. In the embodiments of the present invention, the inventor finds that GP73 plays a key role in blood glucose regulation, and in particular, finds that soluble GP73 can specifically bind to glucagon to form a complex, enhances the blood glucose-rising function and gluconeogenesis function of glucagon and prolongs the half-life of glucagon; and finds soluble GP73 can activate the glucose production in liver and/or kidney and a gluconeogenesis signaling pathway in a glucagon-independent manner. Based on the blood glucose regulation effect of the GP73 described above, the inventor also proves through animal experiments: the GP73 inhibitor can reduce the blood glucose level and glycated hemoglobin level of diabetic mice and have a protective effect on islet ? cells, and thereby having the effect of treating diabetes.Type: ApplicationFiled: September 7, 2022Publication date: January 26, 2023Inventors: Changqing LIN, Zhiwei SUN, Qi GAO, Shuang QIE, Lei XU, JING LI, Jianbo LIN, Hengqi ZHU, Fei ZHENG, Xuechao LIU
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Publication number: 20220372173Abstract: The present invention provides a lectin-magnetic carrier coupling complex for separating glycosylated exosomes from a clinical sample. The lectin-magnetic carrier coupling complex comprises a magnetic carrier and lectins coupled to the outer side of the magnetic carrier. The lectin-magnetic carrier coupling complex provided by the present invention may rapidly, accurately, and automatically separate glycosylated exosomes from a clinical sample with a high separation efficiency; and the separated exosomes are intact in morphology without rupturing or cracking, may be directly used for liquid detection of glycosylated exosomes, or directly used for immunology-related detection, or directly used for nucleotide sequence detection and analysis after extracting nucleic acids from the exosomes.Type: ApplicationFiled: July 13, 2022Publication date: November 24, 2022Inventors: Changqing LIN, Tiansheng CHEN, Kun HAO, He HUANG, Qi GAO, Yanzhao LI, Zhihui XU, Shuang QIE, Guangzhen ZHAO
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LECTIN-MACROMOLECULE CARRIER COUPLING COMPLEX FOR SEPARATING GLYCOSYLATED EXOSOME IN CLINICAL SAMPLE
Publication number: 20220349901Abstract: The present invention relates to a lectin-macromolecular carrier coupling complex for separating glycosylated exosomes from a clinical sample, which comprises a macromolecular carrier and lectins coupled to the outer side of the macromolecular carrier. The complex may simply, conveniently, rapidly, and accurately separate glycosylated exosomes from a clinical sample with a high separation efficiency and a good repeatability; and the separated exosomes are intact in morphology without rupturing or cracking, may be directly used for liquid detection of glycosylated exosomes, or directly used for immunology-related detection, or directly used for gene detection or analysis after extracting related nucleic acids from the exosomes.Type: ApplicationFiled: July 14, 2022Publication date: November 3, 2022Inventors: Changqing LIN, Tiansheng CHEN, Kun HAO, He HUANG, Qi GAO, Yanzhao LI, Zhihui XU, Shuang QIE, Guangzhen ZHAO -
Publication number: 20220017071Abstract: Disclosed are a self-adaptive assistance control device, a computer device and a storage medium for vehicle passing curve. The method comprises: step S10, according to signals from vehicle's sensors, identifying current bend types, and obtaining, corresponding to bend types, a lateral impact degree of the current vehicle according to a lateral acceleration; step S11, obtain an expected longitudinal acceleration based on the lateral impact degree; step S12, according to the expected longitudinal acceleration and a current actual longitudinal acceleration, determining an activation type for current bend assist control; and step S13, according to the activation type, cooperatively controlling an engine torque or/and an ESC braking intensity, so as to realize expected longitudinal control over the vehicle in the road curve.Type: ApplicationFiled: January 28, 2019Publication date: January 20, 2022Inventors: XINGTAI MEI, CHENG DENG, CHUANSHUAI MA, CHANGQING LIN, QIN LI, QI ZENG
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Patent number: 11067579Abstract: A novel serological target marker GP73 used for diagnosing and identifying a simple fatty liver and steatohepatitis in populations with fatty liver and a detection application method thereof. The serological target marker GP73 and the application thereof can replace golden standard liver puncture to identify and diagnose the simple fatty liver and steatohepatitis in populations with fatty liver, reduce the detection pain of a patient, and have an extremely high clinical application value in clinically identifying and diagnosing the simple fatty liver and steatohepatitis in the populations with fatty liver and assisting the treatment of the simple fatty liver and steatohepatitis.Type: GrantFiled: June 19, 2017Date of Patent: July 20, 2021Assignees: BEIJING DITAN HOSPITAL CAPITAL MEDICAL UNIVERSITY, BEIJING HOTGEN BIOTECH CO., LTDInventors: Hongshan Wei, Boan Li, Changqing Lin, Yong Qiao
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Patent number: 10853030Abstract: The present disclosure provides an input method and device. The method specifically comprises: displaying an input interface, where the input interface includes at least one key; in response to a touch operation of a key by a user in an input process, playing an audio corresponding to the key and matching the characteristics of the input interface. Based on keystroke by the user in the input process, the disclosed embodiments provide feedback to the user with animation effect and dynamic audio matching a theme of the current input interface, and enhance key tones in the input process.Type: GrantFiled: March 22, 2016Date of Patent: December 1, 2020Assignee: BEIJING SOGOU TECHNOLOGY DEVELOPMENT CO., LTD.Inventor: Changqing Lin
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Patent number: 10845887Abstract: The present disclosure provides a key processing method and apparatus, and an apparatus for key processing. The key processing method specifically includes processing a non-triggered key in response to a triggering operation by a user on a current key in a current interface where the non-triggered key is a key in the current interface other than the current key, and outputting a processing result of the non-triggered key. The embodiments of the present disclosure not only enrich the current interface, but also enhance the feedback effectiveness and user experience during the use of the interface. Thus, the accuracy of the key operation may be improved.Type: GrantFiled: December 15, 2016Date of Patent: November 24, 2020Assignee: BEIJING SOGOU TECHNOLOGY DEVELOPMENT CO., LTD.Inventor: Changqing Lin
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Patent number: 10697040Abstract: A continuous annealing method for low coercive force cold-rolled electromagnetic pure iron plate and strip. Control parameters of each stages in a continuous annealing process are as follows: 750-850° C. at a heating stage; 750-850° C. at a soaking stage, the soaking time is 100-150 s; an outlet temperature of 575-675° C. at a slow-cooling stage, the cooling speed in slow-cooling stage is 2.5-10° C./s; an outlet temperature of 380-420° C. at a fast-cooling stage, the cooling speed of the fast-cooling stage is 15-25° C./s; and 270-310° C. at an overaging stage. The annealing medium is a non-oxidizing atmosphere composed of H2 and N2. After annealing, the cold-rolled electromagnetic pure iron plate and strip is leveled and pressed such that the leveling elongation rate of the plate and strip is controlled within the range of 0.2±0.1%.Type: GrantFiled: September 1, 2016Date of Patent: June 30, 2020Assignee: BAOSHAN IRON & STEEL CO., LTD.Inventors: Yuanyuan Yan, Gaofei Liang, Guoping Cheng, Changqing Lin
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Patent number: 10329335Abstract: Disclosed are a composition and system for separating and detecting an alpha-fetoprotein variant, comprising a separation reagent and a detection reagent; a system for separating and detecting an alpha-fetoprotein variant and a use thereof; and a kit for separating and detecting the alpha-fetoprotein variant. By means of the composition and system for separating and detecting the alpha-fetoprotein variant, and the use thereof, primary liver cancer can be indicated early on, the sensitivity is high, and the method is rapid, simple and automated.Type: GrantFiled: December 30, 2015Date of Patent: June 25, 2019Assignee: BEIJING HOTGEN BIOTECH CO., LTD.Inventors: Haifeng Luo, Boan Li, Changqing Lin
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Publication number: 20190033983Abstract: The present disclosure provides a key processing method and apparatus, and an apparatus for key processing. The key processing method specifically includes processing a non-triggered key in response to a triggering operation by a user on a current key in a current interface where the non-triggered key is a key in the current interface other than the current key, and outputting a processing result of the non-triggered key. The embodiments of the present disclosure not only enrich the current interface, but also enhance the feedback effectiveness and user experience during the use of the interface. Thus, the accuracy of the key operation may be improved.Type: ApplicationFiled: December 15, 2016Publication date: January 31, 2019Inventor: Changqing LIN
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Publication number: 20180265945Abstract: A continuous annealing method for low coercive force cold-rolled electromagnetic pure iron plate and strip. Control parameters of each stages in a continuous annealing process are as follows: 750-850° C. at a heating stage; 750-850° C. at a soaking stage, the soaking time is 100-150 s; an outlet temperature of 575-675° C. at a slow-cooling stage, the cooling speed in slow-cooling stage is 2.5-10° C./s; an outlet temperature of 380-420° C. at a fast-cooling stage, the cooling speed of the fast-cooling stage is 15-25° C./s; and 270-310° C. at an overaging stage. The annealing medium is a non-oxidizing atmosphere composed of H2 and N2. After annealing, the cold-rolled electromagnetic pure iron plate and strip is leveled and pressed such that the leveling elongation rate of the plate and strip is controlled within the range of 0.2±0.1%.Type: ApplicationFiled: September 1, 2016Publication date: September 20, 2018Inventors: Yuanyuan YAN, Gaofei LIANG, Guoping CHENG, Changqing LIN
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Publication number: 20180225087Abstract: The present disclosure provides an input method and device. The method specifically comprises: displaying an input interface, where the input interface includes at least one key; in response to a touch operation of a key by a user in an input process, playing an audio corresponding to the key and matching the characteristics of the input interface. Based on keystroke by the user in the input process, the disclosed embodiments provide feedback to the user with animation effect and dynamic audio matching a theme of the current input interface, and enhance key tones in the input process.Type: ApplicationFiled: March 22, 2016Publication date: August 9, 2018Inventor: Changqing LIN
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Publication number: 20180009863Abstract: Disclosed are a composition and system for separating and detecting an alpha-fetoprotein variant, comprising a separation reagent and a detection reagent; a system for separating and detecting an alpha-fetoprotein variant and a use thereof; and a kit for separating and detecting the alpha-fetoprotein variant. By means of the composition and system for separating and detecting the alpha-fetoprotein variant, and the use thereof, primary liver cancer can be indicated early on, the sensitivity is high, and the method is rapid, simple and automated.Type: ApplicationFiled: December 30, 2015Publication date: January 11, 2018Inventors: Haifeng LUO, Boan LI, Changqing LIN
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Publication number: 20050181269Abstract: The present invention relates to a microfibrous fuel cell structure of elongated form with a longitudinal axis. Such microfibrous fuel cell comprises electrocatalyst layers supported by a fiber network formed of unidirectional or substantially unidirectional conductive fibers. The conductive fibers of such fiber network are oriented parallelly or substantially parallelly to the longitudinal axis of the fuel cell, therefore allowing such fiber network to conform to the curvature of the microfibrous fuel cell along the radial direction but without causing overbending of the individual fibers.Type: ApplicationFiled: January 6, 2005Publication date: August 18, 2005Inventors: Ray Eshraghi, Changqing Lin, Jung-Chou Lin, Martin Ketterer
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Publication number: 20040058224Abstract: This invention relates to a microfibrous fuel cell having at least one high quality electrocatalyst layer of a dual-layer structure, i.e., a catalyst layer comprising a catalytic material, and an interfacial composition layer comprising a mixture of catalytic material and electrolyte medium. Said high quality electrocatalyst layer can be formed by various catalyzation methods, including diffusion catalyzation, ion-exchange catalyzation, electrodeposition catalyzation, impregnation catalyzation, chemical deposition catalyzation, and alternating catalyst/electrolyte addition catalyzation. The present invention also relates to a fuel cell assembly comprising multiple such microfibrous fuel cells bundled together, and methods for in situ catalyzation of such fuel cell assembly to form high quality electrocatalyst layers of such dual-layer structure.Type: ApplicationFiled: September 24, 2002Publication date: March 25, 2004Inventors: Ray R. Eshraghi, Jung-Chou Lin, Changqing Lin, Michael W. Riley, Erik K. Yarbrough