Patents by Inventor Changxia Yuan

Changxia Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF 1,2,5-TRI-O-BENZOYL-3-DIBENZYLAMINO-3-DEOXYRIBOSE AS INTERMEDIATE FOR PRODUCING 3'-AMINO-3'-DEOXYADENOSINE AND 3'-AMINO-3'-DEOXYGUANOSINE AND THE PROTECTED DERIVATIVES THEREOF
    Publication number: 20230357306
    Abstract: The invention generally relates to improved processes for the preparation of intermediates of a cyclic dinucleotide which is useful as a STING agonist.
    Type: Application
    Filed: February 5, 2020
    Publication date: November 9, 2023
    Inventors: Changxia Yuan, Michael Anthony Schmidt, Adrian Ortiz, Amanda J. Rogers, Jason J. Zhu, Zhongmin Xu, Miao Yu, Eric M. Simmons, Shulin Wu
  • NOVEL SYNTHETIC OPTIONS TOWARDS THE MANUFACTURE OF (6R,10S)-10-{4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)-PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15-(METHENO)PYRAZOLO[4,3-B][1,7]DIAZACYCLOTETRADECIN-5(6H)-ONE
    Publication number: 20220144836
    Abstract: Highly efficient methods are provided for preparing key intermediates in the synthesis of Compound (I), which are broadly applicable and can provide selected components having a variety of substituents groups.
    Type: Application
    Filed: April 10, 2020
    Publication date: May 12, 2022
    Inventors: Nicolas CUNIERE, Yu FAN, Sergei KOLUTUCHIN, Subha MUKHERJEE, Eric M. SIMMONS, Amarjit SINGH, Carolyn S. WEI, Yi XIAO, Changxia YUAN, Bin ZHENG, Simon Albert WAGSCHAL, Diego Fernando Domenico BROGGINI, Duy Chi Trung CAO, Kostiantyn CHERNICHENKO, Sebastien Francois Emmanuel LEMAIRE, Cyril BEN HAÏM
  • PROCESS FOR THE PREPARATION OF A CYCLIC DINUCLEOTIDE
    Publication number: 20220064205
    Abstract: The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.
    Type: Application
    Filed: December 3, 2019
    Publication date: March 3, 2022
    Inventors: Michael Anthony Schmidt, Bin Zheng Kendall Park, Benjamin M. Cohen, Amanda J. Rogers, Changxia Yuan Warren, Jason J. Zhu, Chao Hang, Daniel S. Treitler, Adam Josep Freitag, Geoffrey Eugene Purdum, Miao Yu, Melda Sezen Edmonds, Siwei Guo
  • CYCLIC PEROXIDE OXIDATION OF AROMATIC COMPOUNDS PRODUCTION AND USE THEREOF
    Publication number: 20140296544
    Abstract: The present invention provides a method for converting an aromatic hydrocarbon to a phenol by providing an aromatic hydrocarbon comprising one or more aromatic C—H bonds and one or more activated C—H bonds in a solvent; adding a phthaloyl peroxide to the solvent; converting the phthaloyl peroxide to a di-radical; contacting the di-radical with the one or more aromatic C—H bonds; oxidizing selectively one of the one or more aromatic C—H bonds in preference to the one or more activated C—H bonds; adding a hydroxyl group to the one of the one or more aromatic C—H bonds to form one or more phenols; and purifying the one or more phenols.
    Type: Application
    Filed: August 14, 2013
    Publication date: October 2, 2014
    Inventors: Dionicio Siegel, Andrew M. Camelio, Anders Eliasen, Trevor C. Johnson, Abram Axelrod, Changxia Yuan