Patents by Inventor Channabasavaiah Gurumurthy

Channabasavaiah Gurumurthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for in situ germline genome engineering
    Patent number: 11732273
    Abstract: Disclosed are methods and compositions for in situ germline genome engineering. The disclosed methods and compositions may be utilized for germline genome engineering in a subject having a reproductive organ containing a fertilized zygote, via: (i) isolating or obtaining the reproductive organ from the subject after a time period following insemination of the subject; (ii) introducing a reagent composition into the reproductive organ, the reagent composition comprising a nuclease system and/or an exogeneous polynucleotide; and (iii) electroporating the reproductive organ.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: August 22, 2023
    Assignees: Board of Regents of the University of Nebraska, Tokai University Educational System
    Inventors: Channabasavaiah Gurumurthy, Masato Ohtsuka, Masahiro Sato
  • METHODS AND COMPOSITIONS FOR IN SITU GERMLINE GENOME ENGINEERING
    Publication number: 20200263198
    Abstract: Disclosed are methods and compositions for in situ germline genome engineering. The disclosed methods and compositions may be utilized for germline genome engineering in a subject having a reproductive organ containing a fertilized zygote, via: (i) isolating or obtaining the reproductive organ from the subject after a time period following insemination of the subject; (ii) introducing a reagent composition into the reproductive organ, the reagent composition comprising a nuclease system and/or an exogeneous polynucleotide; and (iii) electroporating the reproductive organ.
    Type: Application
    Filed: February 24, 2020
    Publication date: August 20, 2020
    Inventors: Channabasavaiah Gurumurthy, Masato Ohtsuka, Masahiro Sato