Patents by Inventor Chantalle Havenith

Chantalle Havenith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of purifying preproinsulin
    Patent number: 7803763
    Abstract: The invention relates to a method for the chromatographic purification of preproinsulins, in which higher molecular weight substances are removed from an aqueous solution of preproinsulin by a first chromatography on an anion exchanger in flow-through mode and a subsequent second chromatography on a cation exchanger in adsorption mode, and to a method for preparing insulins, which includes the method for preparing preproinsulins.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: September 28, 2010
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Horst Thurow, Hans Blumenstock, Chantalle Havenith
  • Method of purifying preproinsulin
    Publication number: 20060183666
    Abstract: The invention relates to a method for the chromatographic purification of preproinsulins, in which higher molecular weight substances are removed from an aqueous solution of preproinsulin by a first chromatography on an anion exchanger in flow-through mode and a subsequent second chromatography on a cation exchanger in adsorption mode, and to a method for preparing insulins, which includes the method for preparing preproinsulins.
    Type: Application
    Filed: December 15, 2005
    Publication date: August 17, 2006
    Applicant: Sanofi-aventis Deutschland GmbH
    Inventors: Horst Thurow, Hans Blumenstock, Chantalle Havenith
  • Covalently bridged insulin dimers
    Patent number: 6908897
    Abstract: Provided herein is a heretofore unknown insulin analogue, a pharmaceutical composition comprising such an insulin analogue, as well as processes for preparing such an insulin analogue and such a pharmaceutical composition.
    Type: Grant
    Filed: August 23, 2001
    Date of Patent: June 21, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Dietrich Brandenburg, Chantalle Havenith
  • Method of purifying preproinsulin
    Publication number: 20050080000
    Abstract: The invention relates to a method for the chromatographic purification of preproinsulins, in which higher molecular weight substances are removed from an aqueous solution of preproinsulin by a first chromatography on an anion exchanger in flow-through mode and a subsequent second chromatography on a cation exchanger in adsorption mode, and to a method for preparing insulins, which includes the method for preparing preproinsulins.
    Type: Application
    Filed: August 1, 2003
    Publication date: April 14, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Horst Thurow, Hans Blumenstock, Chantalle Havenith
  • Covalently bridged insulin dimers
    Publication number: 20020160938
    Abstract: The invention provides an analogue of a pharmaceutical active whose molecular weight is less than 25,000 Daltons, the analogue comprising a pharmaceutical active whose molecular weight is less than 25,000 Daltons covalently linked to a pendant molecular group wherein as a result of the administration of the composition to the human or animal body an active complex having a molecular weight of 25,000 Daltons or greater is present in the human or animal circulatory system. The analogue is hepatoselective when administered to the circulatory system. Preferably the analogue is an insulin analogue comprising an insulin or functional equivalent thereof covalently linked to the pendant molecular group wherein the active complex is an insulin complex. Such an insulin analogue may be used in a method of insulin replacement therapy.
    Type: Application
    Filed: August 23, 2001
    Publication date: October 31, 2002
    Inventors: Dietrich Brandenburg, Chantalle Havenith