Abstract: Provided are methods of providing a benefit to the oral cavity by administering to the oral cavity a poorly-soluble calcium compound and subsequently introducing fluoride to the oral cavity.

Abstract: A method of assessing and/or quantifying remineralization in a tooth model by exposing a tooth model to calcium and a calcium-binding fluorophore either sequentially or simultaneously under conditions sufficient to produce a remineralized/demineralized tooth model; exposing the remineralized/demineralized tooth model to a non-calcium binding fluorophore to produce an enhanced tooth model; and assessing and/or quantifying remineralization, demineralization, or both on the enhanced tooth model by determining the location and extent of calcium binding fluorophore and non-calcium binding fluorophore on the enhanced test tooth sample.

Abstract: Provided are compositions comprising an orally-acceptable carrier and an anionic copolymer derived from the polymerization of n-vinyl pyrrolidone (VP) with an anionic monomer compound containing phosphorus. Also provided are uses of such compounds in the oral cavity to inhibit demineralization of a tooth.

Abstract: Provided are compositions comprising an orally-acceptable carrier and a cationic copolymer derived from the polymerization of n-vinyl pyrrolidone (VP) with cationic monomers containing amines or by copolymerization of n-vinyl pyrrolidone (VP) monomers with cationic monomers comprising amides followed by deprotection to amines. Also provided are uses of such compounds in the oral cavity to inhibit demineralization of a tooth.

Abstract: Provided are methods of providing a benefit to the oral cavity by administering to the oral cavity a poorly-soluble calcium compound and subsequently introducing fluoride to the oral cavity.

Abstract: Provided are compositions comprising an orally-acceptable carrier and a cationic copolymer derived from the polymerization of n-vinyl pyrrolidone (VP) with cationic monomers containing amines or by copolymerization of n-vinyl pyrrolidone (VP) monomers with cationic monomers comprising amides followed by deprotection to amines. Also provided are uses of such compounds in the oral cavity to inhibit demineralization of a tooth.

Abstract: Provided are compositions comprising an orally-acceptable carrier and an anionic copolymer derived from the polymerization of n-vinyl pyrrolidone (VP) with an anionic monomer compound containing phosphorus. Also provided are uses of such compounds in the oral cavity to inhibit demineralization of a tooth.