Patents by Inventor Chanyi LI

Chanyi LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12252526
    Abstract: Disclosed are TCR-enriched clonotypes, and an acquisition method and use thereof. Amino acid sequences of the TCR-enriched clonotypes are: CAANRGSGYSTLTF (SEQ ID NO: 1)_CSARGERGEKLFF (SEQ ID NO: 2), CASSSGGSYIPTF (SEQ ID NO: 3)_CASSLAGGHETQYF (SEQ ID NO: 4), CAVNSYNTDKLIF (SEQ ID NO: 5)_CATSREEDNTYEQYF (SEQ ID NO: 6), CAVGGNEKLTF (SEQ ID NO: 7)_CASSQGTGRSSPLHF (SEQ ID NO: 8), or CAASAVGGAQKLVF (SEQ ID NO: 9)_CATSRGTLYGYTF (SEQ ID NO: 10), respectively. The TCR-enriched clonotypes can be used for vaccine development.
    Type: Grant
    Filed: September 15, 2021
    Date of Patent: March 18, 2025
    Assignee: HUNAN YUANPIN CELL TECHNOLOGY CO. LTD.
    Inventors: Zhigang Xue, Jinfeng Xue, Ning Yi, Bo Lv, Chanyi Li, Lingbin Qi, Weilin Li
  • Publication number: 20220081678
    Abstract: The present disclosure provides the use of mesenchymal stem cells (MSC) in the treatment of viral infection and/or complications caused by the viral infection. MSC can highly express multiple antioxidative stress genes and secrete multiple antioxidative stress factors under the stimulation of oxidative stress, inhibit inflammatory reaction and excessive activation of immune cells, thus improving inflammatory indexes and myocardial injury indexes of human bodies. MSC can regulate the expression profile of monocyte genes and monocyte toxicity genes in patients with viral infection, inhibit the excessive immune response, protect alveolar function, and reduce the damage of lung and whole body organs in patients with viral infection.
    Type: Application
    Filed: January 21, 2021
    Publication date: March 17, 2022
    Inventors: Zhigang Xue, Ning Yi, Lingbin Qi, Bo Lv, Chanyi Li, Chunbing Zheng, Weilin Li, Jiangzhou Hua, Tenglong Yan, Yuan Yang
  • Publication number: 20210403529
    Abstract: Disclosed are TCR-enriched clonotypes, and an acquisition method and use thereof. Amino acid sequences of the TCR-enriched clonotypes are: CAANRGSGYSTLTF_CSARGERGEKLFF, CASSSGGSYIPTF_CASSLAGGHETQYF, CAVNSYNTDKLIF_CATSREEDNTYEQYF, CAVGGNEKLTF_CASSQGTGRSSPLHF, or CAASAVGGAQKLVF_CATSRGTLYGYTF, respectively. The TCR-enriched clonotypes can be used for vaccine development.
    Type: Application
    Filed: September 15, 2021
    Publication date: December 30, 2021
    Inventors: Zhigang XUE, Jinfeng XUE, Ning YI, Bo LV, Chanyi LI, Lingbin QI, Weilin LI