Abstract: The disclosure relates to bispecific anti-CD3×CD20 antibodies comprising (i) a single-chain CD3 binding moiety, (ii) a single-chain CD20 binding moiety, and preferably (iii) an Fc region. Aspects of the disclosure further relate to compositions comprising these bispecific antibodies, vectors comprising one or more polynucleotides encoding these bispecific antibodies, as well as uses of these bispecific antibodies for treating a subject suffering from a B cell-related cancer, in particular, a subject who has developed resistance to anti-CD20, e.g., rituximab, therapy.

Abstract: A surgical suturing and knotting integrated device includes a knotting assembly and an operation/control apparatus. The knotting assembly has a suture pre-tied with a slipknot and a loop. In use, the knotting assembly is mounted on a front end of the operation/control apparatus and the front end of the operation/control apparatus is extended into a patient's abdominal cavity to perform laparoscopic surgery. In suturing process, the operation/control apparatus is used to enlarge the loop of the suture, whereby the suture and one end of the suturing needle can be easily passed through the loop. Then, the operation/control apparatus is used to minify the loop and detach the slipknot of the suture from the knotting assembly and change the slipknot into a fixed knot.

Abstract: A surgical suturing and knotting integrated device includes a knotting assembly and an operation/control apparatus. The knotting assembly has a suture pre-tied with a slipknot and a loop. In use, the knotting assembly is mounted on a front end of the operation/control apparatus and the front end of the operation/control apparatus is extended into a patient's abdominal cavity to perform laparoscopic surgery. In suturing process, the operation/control apparatus is used to enlarge the loop of the suture, whereby the suture and one end of the suturing needle can be easily passed through the loop. Then, the operation/control apparatus is used to minify the loop and detach the slipknot of the suture from the knotting assembly and change the slipknot into a fixed knot.

Abstract: Disclosed is a scanning device using radiation beam for backscatter imaging. The scanning device includes a radiation source; a stationary shield plate and a rotary shield body positioned respectively between the radiation source and the subject to be scanned, wherein the stationary shield plate is fixed relative to the radiation source, and the rotary shield body is rotatable relative to the stationary shield plate. The ray passing area permitting the rays from the radiation source to pass through the stationary shield plate is provided on the stationary shield plate, and ray incidence area and ray exit area are respectively provided on the rotary shield body. During the process of the rotating and scanning of the rotary shield body, the ray passing area of the stationary shield plate intersects consecutively with the ray incidence area and the ray exit area of the rotary shield body to form scanning collimation holes. Further, a scanning method using radiation beam for backscatter imaging is also provided.

Abstract: The present invention discloses a scanning device of back-scatter imaging with a radiation beam, comprising: a radiation source; a fixed shield plate and a rotatable shield body disposed between the radiation source and a object to be scanned respectively, wherein the fixed shield plate is stationary with respect to the radiation source and the rotatable shield body is rotatable with respect to the fixed shield plate. The fixed shield plate is provided with a ray passing-through region thereon, which allows for a radiation beam from the radiation source to pass through the fixed shield plate, a ray incidence region and a ray emergence region are arranged on the rotatable shield body respectively, during the rotatable scanning of the rotatable shield body, the ray passing-through region of the fixed shield plate continuously intersects with the ray incidence region and the ray emergence region of the rotatable shield body to generate collimated holes for scanning.

Abstract: Disclosed is a scanning device using radiation beam for backscatter imaging. The scanning device includes a radiation source; a stationary shield plate and a rotary shield body positioned respectively between the radiation source and the subject to be scanned, wherein the stationary shield plate is fixed relative to the radiation source, and the rotary shield body is rotatable relative to the stationary shield plate. The ray passing area permitting the rays from the radiation source to pass through the stationary shield plate is provided on the stationary shield plate, and ray incidence area and ray exit area are respectively provided on the rotary shield body. During the process of the rotating and scanning of the rotary shield body, the ray passing area of the stationary shield plate intersects consecutively with the ray incidence area and the ray exit area of the rotary shield body to form scanning collimation holes. Further, a scanning method using radiation beam for backscatter imaging is also provided.

Abstract: The present invention discloses a scanning device of back-scatter imaging with a radiation beam, comprising: a radiation source; a fixed shield plate and a rotatable shield body disposed between the radiation source and a object to be scanned respectively, wherein the fixed shield plate is stationary with respect to the radiation source and the rotatable shield body is rotatable with respect to the fixed shield plate. The fixed shield plate is provided with a ray passing-through region thereon, which allows for a radiation beam from the radiation source to pass through the fixed shield plate, a ray incidence region and a ray emergence region are arranged on the rotatable shield body respectively, during the rotatable scanning of the rotatable shield body, the ray passing-through region of the fixed shield plate continuously intersects with the ray incidence region and the ray emergence region of the rotatable shield body to generate collimated holes for scanning.

Abstract: A multifunctional forceps set which integrates two important surgical procedures of incision and ligation into a continuous working procedure. The forceps set is co-used with two loop ligatures formed of braided sutures and transfigured from a surgeon's knot. In use, the loop ligatures are side by side loaded in the forceps mouth of the forceps and controlled by the forceps to minify the size of the loop and accomplish ligation function. The forceps set is developed from consolidation of surgical scalpel, forceps and device simulating finger's functions. Also, the forceps set can rapidly perform the procedures of double grasping, incision between grasping, proper ligating divided pedicles and cutting residual sutures of post-ligation. The forceps set enables surgeons to use familiar technique in a challenging operative field such as endoscopic surgery.

Abstract: A hierarchical based advertising system including a primary server, at least one secondary server and at least one terminal is provided. The primary server has advertisement data. The secondary server is coupled with the primary server while the terminal is coupled with the secondary server. The primary server, the secondary server and the terminal are arranged in a hierarchical structure. The primary server transmits the advertisement data to the secondary server to update advertisements displayed on the terminal. A broadcasting method of the hierarchical based advertising system is also provided.

Abstract: The present invention provides a thermoplastic elastomer foaming product, comprising: (a) a hydrogenated styrenic/conjugated diene copolymer, (b) a polyolefin, (c) a plasticizer, and optional additives such as blowing agents, cross-linking agents, promoters, fillers, stabilizers and the like. The thermoplastic elastomer foaming product is soft in nature and has a low specific gravity. The present invention also provides a method of forming the above thermoplastic elastomer foaming product.

Abstract: A low-smoke, halogen-free and flame-retardant thermoplastic elastomer is provided in the present invention. The thermoplastic elastomer includes a polymer having a hydrogenated styrenic/conjugated diene copolymer, an inorganic phosphorus flame-retardant and a flame-retardant auxiliary, wherein a weight of the hydrogenated styrenic/conjugated diene copolymer is 50-100 percents of a weight of the polymer, a weight of the inorganic phosphorus flame-retardant is ranged from 0.3 to 2 times of the weight of the hydrogenated styrenic/conjugated diene copolymer, and a weight of the flame-retardant auxiliary is ranged from 0.05 to 0.4 times of the weight of the hydrogenated styrenic/conjugated diene copolymer.

Abstract: A safety trocar device designed for safe abdominal endoscope operation, including a trocar assembly and a bracket. The trocar assembly includes a sleeve, a trocar and an insufflation needle. A bottom end of the trocar assembly has a thrust section. In use, the trocar assembly is mounted on a suspension arm of the bracket and the bracket is fixed on an operation table. The bracket has an elevation arm under the suspension arm for hooking the abdominal wall of a patient. In operation, an operator continuously turns the trocar assembly with one hand and the abdominal wall is gradually elevated by the elevation arm, whereby the thrust section penetrates through the abdominal wall. Accordingly, the trocar assembly will only drill through the elevated abdominal wall without touching the organs in the abdominal cavity. The trocar assembly is provided with penetration indicator for the operator to judge whether the trocar assembly has truly penetrated through the abdominal wall.

Abstract: A multifunctional forceps set which integrates two important surgical procedures of incision and ligation into a continuous working procedure. The forceps set is co-used with two loop ligatures formed of braided sutures and transfigured from a surgeon's knot. In use, the loop ligatures are side by side loaded in the forceps mouth of the forceps and controlled by the forceps to minify the size of the loop and accomplish ligation function. The forceps set is developed from consolidation of surgical scalpel, forceps and device simulating finger's functions. Also, the forceps set can rapidly perform the procedures of double grasping, incision between grasping, proper ligating divided pedicles and cutting residual sutures of post-ligation. The forceps set enables surgeons to use familiar technique in a challenging operative field such as endoscopic surgery.